DNA Backbone Damage: Repairing Strand Breaks Quiz
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Questions and Answers

Which process involves the repair of both single-strand breaks (SSBs) and double-strand breaks (DSBs) in DNA?

  • Non-homologous end joining
  • Translesion synthesis
  • Base excision repair
  • Homologous recombination (correct)

Which type of breaks in the DNA backbone can be produced by ionizing radiation and certain chemicals?

  • Protein cross-links
  • Single-strand breaks (SSBs) and double-strand breaks (DSBs) (correct)
  • Base pair mismatches
  • Nucleotide deletions

Which repair mechanism is associated with the repair of adenine methylation in DNA?

  • Mismatch repair (correct)
  • Direct repair
  • GATC sequence recognition
  • Nucleotide excision repair

Which sequence is recognized by the mismatch repair system for correction of replication errors?

<p>GATC (C)</p> Signup and view all the answers

In repairing strand breaks, which process involves the joining of broken DNA ends without a homologous template?

<p>Non-homologous end joining (A)</p> Signup and view all the answers

What is the main repair mechanism used by cells for a complete break in a DNA molecule?

<p>Nonhomologous End-Joining (NHEJ) (B)</p> Signup and view all the answers

Which protein binds to single-stranded DNA during the process of homologous recombination?

<p>RecA (A)</p> Signup and view all the answers

In the context of DNA repair, what does GATC sequence recognition refer to?

<p>Recognition of specific DNA sequences for repair (D)</p> Signup and view all the answers

What process involves repairing DNA sequences that are not complementary?

<p>Mismatch repair (C)</p> Signup and view all the answers

Which repair mechanism involves RecA binding to ss-DNA for effective function?

<p>Homologous recombination (C)</p> Signup and view all the answers

How are Single-Strand Breaks (SSBs) in the DNA molecule repaired?

<p>Using the same enzyme systems as Base-Excision Repair (BER) (A)</p> Signup and view all the answers

Which repair mechanism is associated with repairing breaks in a single strand of the DNA molecule?

<p>Base-Excision Repair (BER) (C)</p> Signup and view all the answers

What is the primary role of Base-Excision Repair (BER) in the context of DNA repair?

<p>Repairing Single-Strand Breaks (SSBs) (D)</p> Signup and view all the answers

Which repair process is specifically linked to the repair of breaks in both strands of the DNA double helix?

<p>Homologous Recombination (C)</p> Signup and view all the answers

In which repair mechanism are errors that arise during DNA replication corrected by removing and replacing mispaired nucleotides?

<p>Mismatch Repair (D)</p> Signup and view all the answers

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