DNA Backbone Damage: Repairing Strand Breaks Quiz

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Which process involves the repair of both single-strand breaks (SSBs) and double-strand breaks (DSBs) in DNA?

Non-homologous end joining

Translesion synthesis

Base excision repair

Homologous recombination (correct)

Which type of breaks in the DNA backbone can be produced by ionizing radiation and certain chemicals?

Protein cross-links

Single-strand breaks (SSBs) and double-strand breaks (DSBs) (correct)

Base pair mismatches

Nucleotide deletions

Which repair mechanism is associated with the repair of adenine methylation in DNA?

Mismatch repair (correct)

Direct repair

GATC sequence recognition

Nucleotide excision repair

Which sequence is recognized by the mismatch repair system for correction of replication errors?

GATC Signup and view all the answers

In repairing strand breaks, which process involves the joining of broken DNA ends without a homologous template?

Non-homologous end joining Signup and view all the answers

What is the main repair mechanism used by cells for a complete break in a DNA molecule?

Nonhomologous End-Joining (NHEJ) Signup and view all the answers

Which protein binds to single-stranded DNA during the process of homologous recombination?

RecA Signup and view all the answers

In the context of DNA repair, what does GATC sequence recognition refer to?

Recognition of specific DNA sequences for repair Signup and view all the answers

What process involves repairing DNA sequences that are not complementary?

Mismatch repair Signup and view all the answers

Which repair mechanism involves RecA binding to ss-DNA for effective function?

Homologous recombination Signup and view all the answers

How are Single-Strand Breaks (SSBs) in the DNA molecule repaired?

Using the same enzyme systems as Base-Excision Repair (BER) Signup and view all the answers

Which repair mechanism is associated with repairing breaks in a single strand of the DNA molecule?

Base-Excision Repair (BER) Signup and view all the answers

What is the primary role of Base-Excision Repair (BER) in the context of DNA repair?

Repairing Single-Strand Breaks (SSBs) Signup and view all the answers

Which repair process is specifically linked to the repair of breaks in both strands of the DNA double helix?

Homologous Recombination Signup and view all the answers

In which repair mechanism are errors that arise during DNA replication corrected by removing and replacing mispaired nucleotides?

Mismatch Repair Signup and view all the answers

DNA Backbone Damage: Repairing Strand Breaks Quiz

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