Diseases and Immunity Overview

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Questions and Answers

How do memory cells contribute to immunity?

  • They remember the instructions for antibody production. (correct)
  • They replicate pathogens to keep the immune system active.
  • They destroy pathogens directly.
  • They produce toxins to fight infections.

Antibodies are directly responsible for neutralizing toxins produced by bacteria.

False (B)

What happens when a pathogen with mutated antigens invades the body?

Memory cells will not produce matching antibodies.

An __________ is a molecule found on the surface of a cell that can trigger an immune response.

<p>antigen</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Antigen = A molecule found on the surface of a cell Antibody = A protein made by lymphocytes that binds to antigens Antitoxin = A protein that neutralizes toxins produced by bacteria Memory cell = A cell that retains instructions for antibody production</p> Signup and view all the answers

What is one method to prevent food contamination?

<p>Washing hands with soap (A)</p> Signup and view all the answers

Active immunity is immediate and provides short-term protection.

<p>False (B)</p> Signup and view all the answers

What is the primary purpose of sewage treatment?

<p>To remove harmful pathogens from waste.</p> Signup and view all the answers

Proper waste disposal can reduce the prevalence of __________ that transmit diseases.

<p>pests</p> Signup and view all the answers

Which process helps lymphocytes produce antibodies specific to a pathogen?

<p>Infection (C)</p> Signup and view all the answers

Match the following concepts with their definitions:

<p>Antigens = Molecules on cell membranes that can trigger an immune response Active Immunity = Production of antibodies after infection or vaccination Waste Disposal = Method to reduce the spread of pests Sewage Treatment = Process that removes pathogens from waste</p> Signup and view all the answers

The process of vaccination does not involve active immune response.

<p>False (B)</p> Signup and view all the answers

How can personal hygiene reduce the transmission of diseases?

<p>By catching sneezes and coughs with tissues and washing hands.</p> Signup and view all the answers

What do lymphocytes produce in response to foreign antigens?

<p>Antibodies (A)</p> Signup and view all the answers

Antibodies can attach to antigens causing the pathogens to move freely.

<p>False (B)</p> Signup and view all the answers

What is the role of phagocytes in the immune response?

<p>To engulf and destroy pathogens.</p> Signup and view all the answers

Antibodies signal the presence of pathogens to __________.

<p>phagocytes</p> Signup and view all the answers

Which statement describes the specificity of antibodies?

<p>They are specific to a particular type of antigen (B)</p> Signup and view all the answers

Agglutination makes it more difficult for phagocytosis to occur.

<p>False (B)</p> Signup and view all the answers

What happens to pathogens during agglutination?

<p>They become clumped together and cannot move easily.</p> Signup and view all the answers

What is the definition of a pathogen?

<p>A disease-causing organism (D)</p> Signup and view all the answers

Pathogens can only be transmitted through direct contact.

<p>False (B)</p> Signup and view all the answers

Name one example of a disease caused by indirect contact.

<p>Malaria</p> Signup and view all the answers

The ______ is a mechanical barrier that helps prevent pathogens from entering the body.

<p>skin</p> Signup and view all the answers

Match the type of disease transmission with its description:

<p>Direct contact = Transmission via body fluids. Indirect contact = Transmission through vectors or contaminated surfaces. Aerosols = Transmission through air droplets. Vector = Organism that carries and transmits the pathogen.</p> Signup and view all the answers

Which of the following is NOT a mode of pathogen transmission?

<p>Dietary supplements (C)</p> Signup and view all the answers

HIV can be transmitted through indirect contact.

<p>False (B)</p> Signup and view all the answers

What are the three main ways the body defends itself against disease?

<p>Mechanical barriers, chemical barriers, and immune responses.</p> Signup and view all the answers

What is the primary benefit of herd immunity?

<p>It provides protection to the entire population (D)</p> Signup and view all the answers

Vaccination programs are designed only to control diseases at low levels.

<p>False (B)</p> Signup and view all the answers

What was the disease that was officially eradicated in 1980?

<p>smallpox</p> Signup and view all the answers

Herd immunity occurs when a large enough percentage of the population is __________.

<p>vaccinated</p> Signup and view all the answers

What happens if the percentage of vaccinated individuals drops in a population?

<p>The risk of mass infection increases (B)</p> Signup and view all the answers

The World Health Organisation ran a vaccination programme for __________ starting in the mid-1950s.

<p>smallpox</p> Signup and view all the answers

The successful vaccination program for smallpox began in the 1980s.

<p>False (B)</p> Signup and view all the answers

What is passive immunity?

<p>A fast-acting, short-term defense against pathogens by antibodies from another individual (D)</p> Signup and view all the answers

Passive immunity involves the body creating its own antibodies.

<p>False (B)</p> Signup and view all the answers

What is one method to treat severe diarrhoea caused by cholera?

<p>Oral rehydration therapy</p> Signup and view all the answers

Cholera is caused by the bacteria __________.

<p>Vibrio cholerae</p> Signup and view all the answers

How does cholera primarily cause diarrhoea?

<p>By infecting the small intestine and disrupting normal function (D)</p> Signup and view all the answers

What essential components are included in oral rehydration therapy?

<p>Salt and sugar</p> Signup and view all the answers

The loss of watery faeces from the anus is known as __________.

<p>diarrhoea</p> Signup and view all the answers

Match the terms with their definitions:

<p>Passive Immunity = Short-term defense using antibodies from another individual Cholera = Diarrhoeal disease caused by Vibrio cholerae Oral Rehydration Therapy = Treatment involving salt and sugar to restore fluids Diarrhoea = Loss of watery faeces from the anus</p> Signup and view all the answers

Flashcards

Pathogen

A disease-causing organism that can be transmitted from one host to another.

Transmissible diseases

Diseases that are caused by pathogens and can be spread from one organism to another.

Direct Contact Transmission

The direct transfer of a pathogen from an infected host to a healthy host via bodily fluids, e.g., blood, semen.

Indirect Contact Transmission

Indirect transmission occurs when a pathogen is transferred from an infected host to a healthy host via an intermediate medium, e.g., contaminated surfaces, air, or insects.

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Skin

The outermost layer of the body that acts as a physical barrier, preventing pathogens from entering.

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Mechanical Barriers

Barriers that physically prevent pathogens from entering the body.

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Body Fluid Transmission

A method of pathogen transmission involving transfer of bodily fluids like blood or semen. This is often associated with direct contact.

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Vector Transmission

The spread of pathogens via an intermediate medium such as air, contaminated surfaces, water, food, or insects.

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Hygienic Food Preparation

Keeping food safe from harmful bacteria and fungi by using proper washing, cooking and preparation methods.

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Personal Hygiene

Practices like washing hands with soap and using tissues for coughs and sneezes to prevent the spread of germs like colds and flu.

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Waste Disposal

Properly disposing of waste, such as food scraps, reduces the presence of pests like flies that can spread diseases.

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Sewage Treatment

Treatment of sewage removes harmful pathogens from wastewater before it's released into the environment, reducing the risk of waterborne diseases.

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Active Immunity

The ability of the body to produce antibodies and memory cells to fight off future infections.

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Antigens

Molecules on cell surfaces, such as proteins, that can be recognized by the immune system.

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Antibodies

Proteins produced by the immune system that bind to specific antigens and help neutralize them.

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How does the immune system recognize foreign antigens?

The immune system recognizes and attacks foreign antigens.

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Lymphocytes

Specialized white blood cells that produce antibodies.

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Agglutination

The process where antibodies bind to antigens, causing pathogens to clump together.

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Phagocytes

White blood cells that engulf and destroy pathogens.

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Immunity

The ability of the body to resist infection and disease.

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Humoral immunity

A type of immunity that involves the production of antibodies by lymphocytes.

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Cell-mediated immunity

A type of immunity that involves the activation of T cells and other immune cells.

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Antibody

A protein produced by lymphocytes that specifically binds to an antigen, marking it for destruction.

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Antitoxin

A protein produced by the immune system that neutralizes toxins released by bacteria.

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Memory cells

Immune cells that retain the 'memory' of a specific pathogen, allowing for a faster and stronger immune response upon re-exposure.

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Herd Immunity

A situation where a large enough percentage of the population is immune to a disease, making it difficult for the disease to spread.

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Vaccination

The process of introducing weakened or inactive forms of a pathogen into the body to trigger an immune response, resulting in long-term protection against that disease.

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Pandemic

A disease outbreak that spreads rapidly and widely across a large geographic area.

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Epidemic

A disease outbreak that occurs in a particular geographic area or among a specific population.

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Contagious Disease

A disease that can be transmitted from one person to another directly or indirectly.

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Eradication

A disease that has been eliminated from the world.

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Controlled Disease

A disease with a low prevalence due to widespread immunization.

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Passive immunity

A type of immunity where antibodies are acquired from another individual, providing immediate but short-term protection against pathogens.

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Breastfeeding and immunity

The transfer of antibodies from mother to infant through breast milk, providing initial protection against infections.

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Cholera

A severe form of diarrhea caused by the bacterium Vibrio cholerae, leading to significant fluid and electrolyte loss.

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Diarrhea

The loss of watery feces from the anus, often a symptom of various illnesses.

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Oral rehydration therapy (ORT)

Treatment for severe diarrhea involving a drink with a small amount of salt and sugar, replacing lost fluids and electrolytes.

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Vibrio cholerae

The bacteria responsible for causing cholera.

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How Vibrio cholerae causes diarrhea

The process by which Vibrio cholerae causes diarrhea by attaching to the small intestine, producing toxins that lead to fluid loss.

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Mechanism of cholera-induced diarrhea

The mechanism by which cholera leads to diarrhea, involving the bacterium's toxins interfering with the small intestine's ability to absorb fluids.

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Study Notes

Diseases & Immunity

  • Pathogens are disease-causing organisms that can be passed from one host to another, causing transmissible diseases.
  • Pathogens can spread through direct contact (e.g., bodily fluids, like in HIV/AIDS), or indirect contact (e.g., contaminated surfaces, air, food, water, insects).
  • Methods of transmission include droplets in the air, food or water, touching contaminated surfaces, and insect bites. Common diseases spread through these routes include the common cold, influenza, cholera, typhoid, dysentery, athletes' foot, salmonella, malaria, and dengue fever.
  • The body defends itself against disease in three main ways: mechanical barriers (e.g., skin, nose hairs), chemical barriers (e.g., mucus, stomach acid), and cells (e.g., white blood cells via phagocytosis and antibody production).
  • Controlling the spread of diseases involves measures like clean water supplies, hygienic food preparation, personal hygiene, waste disposal, and sewage treatment. These measures aim to prevent pathogens from spreading.

Active Immunity

  • Active immunity involves producing antibodies and memory cells in response to an infection or vaccination.
  • This response is slower but provides long-lasting immunity.
  • Active immunity can be triggered when the body is infected with a pathogen, or through vaccination.
  • Vaccination introduces a harmless form of a pathogen to stimulate an immune response and create memory cells. This allows the body to respond quickly to a subsequent infection.

Antigens & Antibodies

  • Antigens are molecules on cell surfaces, often proteins.
  • Different individuals have different antigens.
  • Pathogens have antigens on their surface that lymphocytes (white blood cells) can recognize.
  • Lymphocytes produce antibodies that are complementary in shape to the antigens on the pathogen's surface. Antibodies bind to, and thus help to neutralize, the pathogen. This process and the resulting pathogen clumping is called agglutination.
  • Antibodies enhance the activity of phagocytes and clump pathogens together to make them easier to engulf and destroy.

The role of antibodies

  • Antibodies attach to antigens and cause agglutination of pathogens, immobilizing them.
  • This helps chemical signals from the antibody signal the presence of pathogens to phagocytic cells, leading to them ingesting the pathogens.
  • Phagocytes move to the site of the infection and engulf and destroy microorganisms, often after they've been clumped by antibodies.

Vaccination

  • Vaccinations introduce harmless pathogens or antigens to stimulate an immune response.
  • Vaccines produce memory cells and this creates a long-lasting immunity.
  • The proportion of vaccinated people in a population is important to prevent diseases from spreading (Herd Immunity). Having a high proportion of people vaccinated protects those who cannot be vaccinated.

Preventing the spread of Disease

  • Herd immunity occurs when a large percentage of a population is vaccinated, thus protecting the entire population.
  • It makes it difficult for the pathogen to spread because there are fewer susceptible individuals.

Passive Immunity & Breastfeeding

  • Passive immunity is a short-term defense where antibodies are acquired from another individual, such as through breast milk.
  • The infant gets antibodies from the mother.
  • The body does not produce its own antibodies or memory cells.
  • This is beneficial for infant health.

Cholera

  • Cholera is a disease caused by the bacterium Vibrio cholerae.
  • Cholera causes severe diarrhea, with a loss of water and ions from the body.
  • If severe, prolonged, Cholera can be fatal.
  • Oral rehydration therapy is an effective treatment for cholera. This consists of a salt and sugar solution.
  • Vibrio cholerae bacteria releases toxins that cause chloride ions to leave the cells lining the small intestine, drawing water into the intestines to help create watery diarrhea.

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