Discovering the Functions of α1-Acid Glycoprotein (AAG) Quiz

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Questions and Answers

Which plasma protein acts as an antioxidant and prevents ROS?

  • Fibrinogen
  • Transferrin
  • Ferritin (correct)
  • Cp

Which disorder is associated with decreased plasma concentrations of Cp?

  • Dysfibrinogenemias
  • Wilson’s disease (correct)
  • Hereditary variants of fibrinogen
  • Fibrinogen disorders

Which protein is an acute phase response (APR) marker that increases during inflammation?

  • Procalcitonin
  • C-reactive protein (correct)
  • Serum amyloid A
  • Interleukin-6 (IL-6)

Which plasma protein has increased concentrations in bacterial infections compared to viral infections?

<p>C-reactive protein (D)</p> Signup and view all the answers

Which protein measurement is more sensitive and specific than measurements of ESR and plasma viscosity?

<p>C-reactive protein (C)</p> Signup and view all the answers

Which plasma proteins are associated with increased vascular permeability?

<p>Prostaglandins, histamine, and other vasoactive substances (B)</p> Signup and view all the answers

Which plasma protein is generally higher in bacterial infections than viral infections?

<p>C-reactive protein (A)</p> Signup and view all the answers

Which plasma protein is associated with the risk of cardiovascular disease?

<p>C-reactive protein (A)</p> Signup and view all the answers

Which plasma protein acts as an antioxidant and binds iron or heme?

<p>Ferritin (B)</p> Signup and view all the answers

Which plasma protein has decreased concentrations during an acute phase response (APR)?

<p>C-reactive protein (A)</p> Signup and view all the answers

Which cell type primarily synthesizes α1-Acid Glycoprotein (AAG)?

<p>Hepatocytes (C)</p> Signup and view all the answers

What is the main function of α1-Acid Glycoprotein (AAG)?

<p>Cofactor for lipoprotein lipase (B)</p> Signup and view all the answers

Which of the following is NOT a function of α1-Acid Glycoprotein (AAG)?

<p>Downregulation of the immune response (B)</p> Signup and view all the answers

What is the clinical significance of increased plasma concentrations of α1-Acid Glycoprotein (AAG)?

<p>Indicator of the clinical activity of ulcerative colitis (A)</p> Signup and view all the answers

What is the major β-globulin in the blood?

<p>Transferrin (B)</p> Signup and view all the answers

What is the function of ferritin?

<p>Stores iron for future use (A)</p> Signup and view all the answers

What can lead to decreased plasma concentrations of transferrin?

<p>Chronic liver disease (B)</p> Signup and view all the answers

What is the clinical significance of increased plasma concentrations of transferrin?

<p>Indicator of the clinical activity of ulcerative colitis (C)</p> Signup and view all the answers

What can lead to decreased plasma concentrations of α1-Acid Glycoprotein (AAG)?

<p>Estrogens (A)</p> Signup and view all the answers

What is formed when ferritin is partially degraded in secondary lysosomes?

<p>Hemosiderin (B)</p> Signup and view all the answers

Which plasma protein is associated with Wilson's disease?

<p>Cp (A)</p> Signup and view all the answers

Which plasma protein is functionally abnormal in dysfibrinogenemias?

<p>Fibrinogen (B)</p> Signup and view all the answers

Which plasma protein is associated with thrombosis?

<p>Fibrinogen (A)</p> Signup and view all the answers

Which plasma protein is impaired in congenital afibrinogenemia?

<p>Fibrinogen (C)</p> Signup and view all the answers

Which plasma protein is increased during an acute phase response (APR)?

<p>Ferritin (B)</p> Signup and view all the answers

Which plasma protein is associated with increased vascular permeability?

<p>Albumin (B)</p> Signup and view all the answers

Which plasma protein measurement is more sensitive and specific than measurements of ESR and plasma viscosity?

<p>C-reactive protein (D)</p> Signup and view all the answers

Which plasma protein is generally higher in bacterial infections than viral infections?

<p>C-reactive protein (A)</p> Signup and view all the answers

Which plasma protein is associated with the risk of cardiovascular disease?

<p>C-reactive protein (A)</p> Signup and view all the answers

Which plasma protein has decreased concentrations during an acute phase response (APR)?

<p>Serum amyloid A (D)</p> Signup and view all the answers

Which plasma protein is primarily synthesized by hepatocytes?

<p>α1-Acid Glycoprotein (AAG) (B)</p> Signup and view all the answers

What is the main function of α1-Acid Glycoprotein (AAG)?

<p>Cofactor for lipoprotein lipase (A)</p> Signup and view all the answers

Which plasma protein acts as an antioxidant and binds iron or heme?

<p>Haptoglobin (Hp) (D)</p> Signup and view all the answers

What is the major β-globulin in the blood?

<p>Transferrin (A)</p> Signup and view all the answers

What is the clinical significance of increased plasma concentrations of α1-Acid Glycoprotein (AAG)?

<p>Indicator of the clinical activity of ulcerative colitis (B)</p> Signup and view all the answers

What can lead to decreased plasma concentrations of α1-Acid Glycoprotein (AAG)?

<p>Chronic liver disease (B)</p> Signup and view all the answers

What is the function of ferritin?

<p>Storage of iron (D)</p> Signup and view all the answers

Which plasma protein has decreased concentrations during an acute phase response (APR)?

<p>C-reactive protein (CRP) (C)</p> Signup and view all the answers

What is formed when ferritin is partially degraded in secondary lysosomes?

<p>Hemosiderin (A)</p> Signup and view all the answers

What can lead to decreased plasma concentrations of transferrin?

<p>Chronic liver disease (A)</p> Signup and view all the answers

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