40 Questions
Which plasma protein acts as an antioxidant and prevents ROS?
Ferritin
Which disorder is associated with decreased plasma concentrations of Cp?
Wilson’s disease
Which protein is an acute phase response (APR) marker that increases during inflammation?
C-reactive protein
Which plasma protein has increased concentrations in bacterial infections compared to viral infections?
C-reactive protein
Which protein measurement is more sensitive and specific than measurements of ESR and plasma viscosity?
C-reactive protein
Which plasma proteins are associated with increased vascular permeability?
Prostaglandins, histamine, and other vasoactive substances
Which plasma protein is generally higher in bacterial infections than viral infections?
C-reactive protein
Which plasma protein is associated with the risk of cardiovascular disease?
C-reactive protein
Which plasma protein acts as an antioxidant and binds iron or heme?
Ferritin
Which plasma protein has decreased concentrations during an acute phase response (APR)?
C-reactive protein
Which cell type primarily synthesizes α1-Acid Glycoprotein (AAG)?
Hepatocytes
What is the main function of α1-Acid Glycoprotein (AAG)?
Cofactor for lipoprotein lipase
Which of the following is NOT a function of α1-Acid Glycoprotein (AAG)?
Downregulation of the immune response
What is the clinical significance of increased plasma concentrations of α1-Acid Glycoprotein (AAG)?
Indicator of the clinical activity of ulcerative colitis
What is the major β-globulin in the blood?
Transferrin
What is the function of ferritin?
Stores iron for future use
What can lead to decreased plasma concentrations of transferrin?
Chronic liver disease
What is the clinical significance of increased plasma concentrations of transferrin?
Indicator of the clinical activity of ulcerative colitis
What can lead to decreased plasma concentrations of α1-Acid Glycoprotein (AAG)?
Estrogens
What is formed when ferritin is partially degraded in secondary lysosomes?
Hemosiderin
Which plasma protein is associated with Wilson's disease?
Cp
Which plasma protein is functionally abnormal in dysfibrinogenemias?
Fibrinogen
Which plasma protein is associated with thrombosis?
Fibrinogen
Which plasma protein is impaired in congenital afibrinogenemia?
Fibrinogen
Which plasma protein is increased during an acute phase response (APR)?
Ferritin
Which plasma protein is associated with increased vascular permeability?
Albumin
Which plasma protein measurement is more sensitive and specific than measurements of ESR and plasma viscosity?
C-reactive protein
Which plasma protein is generally higher in bacterial infections than viral infections?
C-reactive protein
Which plasma protein is associated with the risk of cardiovascular disease?
C-reactive protein
Which plasma protein has decreased concentrations during an acute phase response (APR)?
Serum amyloid A
Which plasma protein is primarily synthesized by hepatocytes?
α1-Acid Glycoprotein (AAG)
What is the main function of α1-Acid Glycoprotein (AAG)?
Cofactor for lipoprotein lipase
Which plasma protein acts as an antioxidant and binds iron or heme?
Haptoglobin (Hp)
What is the major β-globulin in the blood?
Transferrin
What is the clinical significance of increased plasma concentrations of α1-Acid Glycoprotein (AAG)?
Indicator of the clinical activity of ulcerative colitis
What can lead to decreased plasma concentrations of α1-Acid Glycoprotein (AAG)?
Chronic liver disease
What is the function of ferritin?
Storage of iron
Which plasma protein has decreased concentrations during an acute phase response (APR)?
C-reactive protein (CRP)
What is formed when ferritin is partially degraded in secondary lysosomes?
Hemosiderin
What can lead to decreased plasma concentrations of transferrin?
Chronic liver disease
Test your knowledge on α1-Acid Glycoprotein (AAG) and its functions in the body. Learn about its synthesis, role in platelet aggregation and mitosis, inhibition of viruses and parasites, and its effects on lipoprotein lipase, steroid hormone metabolism, neutrophil phagocytosis, and the immune response.
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