20 Questions
Which organ mainly synthesizes α1-Acid Glycoprotein (AAG)?
Liver
What is the function of α1-Acid Glycoprotein (AAG)?
Inhibiting viruses and parasites
Which hormone can affect the concentration of α1-Acid Glycoprotein (AAG) in the plasma?
Estrogen
What is the major β-globulin in the plasma?
Transferrin
What is the clinical significance of increased α1-Acid Glycoprotein (AAG) plasma concentrations?
Indicator of ulcerative colitis
What is the function of ferritin?
Storage of iron
What is formed when ferritin is partially degraded in secondary lysosomes?
Hemosiderin
What can cause decreased plasma concentrations of transferrin?
Protein-losing enteropathies
What is the function of transferrin?
Transport of lipophilic compounds
What can increase plasma concentrations of transferrin?
Iron deficiency anemia
Which plasma protein acts as an antioxidant and prevents ROS?
Ferritin
Which disorder is associated with decreased plasma concentrations of Cp?
Wilson’s disease
Which protein is functionally abnormal in fibrinogen disorders?
Fibrinogen
Which disorder is characterized by congenital afibrinogenemia?
Congenital afibrinogenemia
Which protein is increased during the acute phase response (APR)?
C-reactive protein
Which proteins are decreased during the acute phase response (APR)?
Albumin, prealbumin, transferrin
Which marker is more sensitive and specific than the erythrocyte sedimentation rate (ESR) and plasma viscosity measurements?
C-reactive protein
Which infection is generally associated with higher serum CRP concentrations?
Bacterial infection
What is the general function of CRP?
Defence against bacteria and foreign substances
Which protein is associated with an increased risk of cardiovascular disease?
C-reactive protein
Test your knowledge on α1-Acid Glycoprotein (AAG) and its functions in the body. Learn about its synthesis, role in platelet aggregation and mitosis, inhibition of viruses and parasites, and its effects on lipoprotein lipase, steroid hormone metabolism, neutrophil phagocytosis, and the immune response.
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