Podcast
Questions and Answers
Which enzyme is involved in direct reversal of pyrimidine dimers formation?
Which enzyme is involved in direct reversal of pyrimidine dimers formation?
- Photolytic enzyme
- Photoreactivating polymerase
- Photoreactivating enzyme
- Photolyase (correct)
What is the main consequence of UV light-induced formation of pyrimidine dimers on DNA structure?
What is the main consequence of UV light-induced formation of pyrimidine dimers on DNA structure?
- Enhanced transcription
- Increased stability
- Distorted DNA chain structure (correct)
- No impact on DNA structure
Which repair mechanism occurs without the need for a template?
Which repair mechanism occurs without the need for a template?
- Nucleotide excision repair
- Mismatch repair
- Base excision repair
- Direct reversal repair (correct)
Which chemical process can be reverted by photoreactivation through utilization of light energy?
Which chemical process can be reverted by photoreactivation through utilization of light energy?
Which enzyme is responsible for restoring the original guanine base by transferring the methylation product in the direct reversal repair mechanism?
Which enzyme is responsible for restoring the original guanine base by transferring the methylation product in the direct reversal repair mechanism?
Which type of direct reversal repair does not occur in humans?
Which type of direct reversal repair does not occur in humans?
What happens to the enzyme once the alkyl group is transferred to it?
What happens to the enzyme once the alkyl group is transferred to it?
Which type of repair mechanism involves the recognition and removal of a single damaged base?
Which type of repair mechanism involves the recognition and removal of a single damaged base?
What type of repair mechanism is used to repair the formation of pyrimidine dimers from UV light within humans?
What type of repair mechanism is used to repair the formation of pyrimidine dimers from UV light within humans?
Which enzyme is responsible for removing the damaged base forming an AP site in Base Excision Repair?
Which enzyme is responsible for removing the damaged base forming an AP site in Base Excision Repair?
What is the general mechanism by which repairs are made when one of the double helix strands is damaged?
What is the general mechanism by which repairs are made when one of the double helix strands is damaged?
Which repair mechanism recognizes multiple damaged bases and cleaves them on both sides before resynthesis?
Which repair mechanism recognizes multiple damaged bases and cleaves them on both sides before resynthesis?
Which repair mechanism involves the incorporation of mismatched bases into the DNA strand during replication?
Which repair mechanism involves the incorporation of mismatched bases into the DNA strand during replication?
What is the main mechanism for repairing damage to both DNA strands?
What is the main mechanism for repairing damage to both DNA strands?
Which repair mechanism connects the break ends without a homologous template?
Which repair mechanism connects the break ends without a homologous template?
What can happen through homologous recombination that is prevented by Classical Nonhomologous End Joining?
What can happen through homologous recombination that is prevented by Classical Nonhomologous End Joining?
Which repair mechanism is prone to error but protects genome integrity?
Which repair mechanism is prone to error but protects genome integrity?
What can alternative repair mechanisms like Single Strand Annealing lead to?
What can alternative repair mechanisms like Single Strand Annealing lead to?
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