Direct Reversal DNA Repair Mechanism Quiz
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Questions and Answers

Which enzyme is involved in direct reversal of pyrimidine dimers formation?

  • Photolytic enzyme
  • Photoreactivating polymerase
  • Photoreactivating enzyme
  • Photolyase (correct)

What is the main consequence of UV light-induced formation of pyrimidine dimers on DNA structure?

  • Enhanced transcription
  • Increased stability
  • Distorted DNA chain structure (correct)
  • No impact on DNA structure

Which repair mechanism occurs without the need for a template?

  • Nucleotide excision repair
  • Mismatch repair
  • Base excision repair
  • Direct reversal repair (correct)

Which chemical process can be reverted by photoreactivation through utilization of light energy?

<p>Methylation of guanine bases (B)</p> Signup and view all the answers

Which enzyme is responsible for restoring the original guanine base by transferring the methylation product in the direct reversal repair mechanism?

<p>Methyl guanine methyl transferase (MGMT) (B)</p> Signup and view all the answers

Which type of direct reversal repair does not occur in humans?

<p>Photoreactivation (B)</p> Signup and view all the answers

What happens to the enzyme once the alkyl group is transferred to it?

<p>It becomes inactivated (A)</p> Signup and view all the answers

Which type of repair mechanism involves the recognition and removal of a single damaged base?

<p>Base Excision Repair (D)</p> Signup and view all the answers

What type of repair mechanism is used to repair the formation of pyrimidine dimers from UV light within humans?

<p>Nucleotide Excision Repair (A)</p> Signup and view all the answers

Which enzyme is responsible for removing the damaged base forming an AP site in Base Excision Repair?

<p>Glycosylases (A)</p> Signup and view all the answers

What is the general mechanism by which repairs are made when one of the double helix strands is damaged?

<p>Excision Repair (D)</p> Signup and view all the answers

Which repair mechanism recognizes multiple damaged bases and cleaves them on both sides before resynthesis?

<p>Nucleotide Excision Repair (D)</p> Signup and view all the answers

Which repair mechanism involves the incorporation of mismatched bases into the DNA strand during replication?

<p>Mismatch Repair (A)</p> Signup and view all the answers

What is the main mechanism for repairing damage to both DNA strands?

<p>Homologous Recombination (B)</p> Signup and view all the answers

Which repair mechanism connects the break ends without a homologous template?

<p>Classical Nonhomologous End Joining (B)</p> Signup and view all the answers

What can happen through homologous recombination that is prevented by Classical Nonhomologous End Joining?

<p>Chromosomal translocations (C)</p> Signup and view all the answers

Which repair mechanism is prone to error but protects genome integrity?

<p>Classical Nonhomologous End Joining (B)</p> Signup and view all the answers

What can alternative repair mechanisms like Single Strand Annealing lead to?

<p>Loss of genetic information (D)</p> Signup and view all the answers

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