Podcast
Questions and Answers
Which process directly reverses pyrimidine dimers caused by UV light?
Which process directly reverses pyrimidine dimers caused by UV light?
- Excision repair
- Photoreactivation (correct)
- Methylation of guanine bases
- Methyl guanine methyl transferase (MGMT)
What is the bacterial equivalent enzyme for the protein methyl guanine methyl transferase (MGMT)?
What is the bacterial equivalent enzyme for the protein methyl guanine methyl transferase (MGMT)?
- Excision repair
- Methylation of guanine bases
- Photoreactivation
- Methyl guanine methyl transferase (MGMT) (correct)
Which DNA repair mechanism does not require a template and does not involve the breakage of the phosphodiester backbone?
Which DNA repair mechanism does not require a template and does not involve the breakage of the phosphodiester backbone?
- Photoreactivation
- Excision repair
- Direct reversal mechanisms (correct)
- Methylation of guanine bases
What type of DNA damage does UV-B light cause?
What type of DNA damage does UV-B light cause?
How is the damage caused by UV-A light referred to?
How is the damage caused by UV-A light referred to?
Which type of DNA damage can be reversed by photoreactivation?
Which type of DNA damage can be reversed by photoreactivation?
What may low-level ionizing radiation induce?
What may low-level ionizing radiation induce?
Which repair mechanism is responsible for correcting errors of DNA replication and recombination?
Which repair mechanism is responsible for correcting errors of DNA replication and recombination?
What is the major pathway for repair of modified bases, uracil misincorporation, oxidation, alkylation, hydrolysis, or deamination damage?
What is the major pathway for repair of modified bases, uracil misincorporation, oxidation, alkylation, hydrolysis, or deamination damage?
Which repair mechanism recognizes bulky lesions that block DNA replication?
Which repair mechanism recognizes bulky lesions that block DNA replication?
What is the outcome of the action of DNA glycosylases during base excision repair?
What is the outcome of the action of DNA glycosylases during base excision repair?
What can cause DNA damage in human cells?
What can cause DNA damage in human cells?
What is the consequence of DNA repair process being constantly active?
What is the consequence of DNA repair process being constantly active?
What can a cell with a large amount of DNA damage or ineffective repair enter into?
What can a cell with a large amount of DNA damage or ineffective repair enter into?
Which of the following is an example of exogenous DNA damage?
Which of the following is an example of exogenous DNA damage?