Podcast
Questions and Answers
What is the typical incubation period for respiratory diphtheria?
What is the typical incubation period for respiratory diphtheria?
2-5 days
What is the molecular weight of the diphtheria toxin?
What is the molecular weight of the diphtheria toxin?
62,000 kDa
What is the local effect of the diphtheria toxin on the respiratory epithelium?
What is the local effect of the diphtheria toxin on the respiratory epithelium?
Destruction of the respiratory epithelium with a subsequent inflammatory response
What is the result of the systemic absorption of the diphtheria toxin?
What is the result of the systemic absorption of the diphtheria toxin?
How long may certain chronic carriers shed C. diphtheriae without antibiotic therapy?
How long may certain chronic carriers shed C. diphtheriae without antibiotic therapy?
What is the mechanism of action of the diphtheria toxin on cells?
What is the mechanism of action of the diphtheria toxin on cells?
What is the primary site of colonization of Corynebacterium diphtheriae in respiratory diphtheria?
What is the primary site of colonization of Corynebacterium diphtheriae in respiratory diphtheria?
What is the role of the beta-prophage gene (tox) in toxigenic strains of C. diphtheriae?
What is the role of the beta-prophage gene (tox) in toxigenic strains of C. diphtheriae?
What is the characteristic finding in tonsillar and pharyngeal diphtheria?
What is the characteristic finding in tonsillar and pharyngeal diphtheria?
What is a potential complication of cervical lymphadenopathy and swelling of the soft tissue of the neck in respiratory diphtheria?
What is a potential complication of cervical lymphadenopathy and swelling of the soft tissue of the neck in respiratory diphtheria?
What is a systemic feature of diphtheria due to dissemination of toxin?
What is a systemic feature of diphtheria due to dissemination of toxin?
What is a rare complication of diphtheria?
What is a rare complication of diphtheria?