Dental Diphtheria,Pseudomonas, Pertussis, Chlamydia, Mycoplasma 2023

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Which agar is used to culture Corynebacterium diphtheriae?

Tinsdale agar

What is the characteristic shape of Corynebacterium diphtheriae?

Rod-like, arrange themselves in palisades and have club shaped swellings at their poles

Where does Corynebacterium diphtheriae colonize in the human body?

Throat

How is Corynebacterium diphtheriae transmitted from one human to another?

<p>Direct contact</p> Signup and view all the answers

What can form in the throat due to Corynebacterium diphtheriae infection?

<p>Pseudomembrane</p> Signup and view all the answers

What is the vaccine for diphtheria made of?

<p>Toxoid</p> Signup and view all the answers

Which strains of Corynebacterium diphtheriae produce the diphtheria toxin?

<p>Only strains with a beta-phage</p> Signup and view all the answers

What is the role of the diphtheria toxin in protein synthesis?

<p>Toxin ADP-ribosylates Elongation Factor 2 (EF2)</p> Signup and view all the answers

What is a toxoid used in the diphtheria vaccine?

<p>Formalin-treated toxin</p> Signup and view all the answers

Which type of bacteria is Corynebacterium diphtheriae?

<p>Gram positive rod</p> Signup and view all the answers

Where is Pseudomonas aeruginosa commonly found?

<p>Water and soil</p> Signup and view all the answers

What percentage of people have Corynebacterium diphtheriae as normal flora in their gastrointestinal tract?

<p>10%</p> Signup and view all the answers

Which term describes Pseudomonas aeruginosa as a pathogen?

<p>Opportunistic pathogen</p> Signup and view all the answers

How is Pseudomonas aeruginosa transmitted from one human to another?

<p>No human to human transmission</p> Signup and view all the answers

In which population does Pseudomonas aeruginosa chronically colonize the lungs?

<p>Children with cystic fibrosis</p> Signup and view all the answers

What can result from Pseudomonas aeruginosa bacteremias and sepsis?

<p>High mortality</p> Signup and view all the answers

What is the role of the alginate capsule produced by some strains of Pseudomonas aeruginosa?

<p>Blocks phagocytosis</p> Signup and view all the answers

Which factor helps Pseudomonas aeruginosa penetrate deeper into tissues in burn patients?

<p>Elastase</p> Signup and view all the answers

What is the characteristic odor produced by Pseudomonas aeruginosa?

<p>Fruity odor</p> Signup and view all the answers

What is the role of the pyocyanin pigment produced by Pseudomonas aeruginosa?

<p>Produces a blue-green pigment</p> Signup and view all the answers

Which type of bacteria is Pseudomonas aeruginosa?

<p>Gram negative rod, with polar flagella</p> Signup and view all the answers

In which population is biofilm formation by Pseudomonas aeruginosa believed to occur?

<p>Lungs of Cystic fibrosis patients</p> Signup and view all the answers

What is the function of Pseudomonas Exotoxin A?

<p>ADP-ribosylates Elongation Factor-2</p> Signup and view all the answers

Which bacterium causes whooping cough?

<p>Bordetella pertussis</p> Signup and view all the answers

What is the main mode of transmission for whooping cough?

<p>Person to person</p> Signup and view all the answers

Which organ does Bordetella pertussis colonize in the human body?

<p>Ciliated epithelium of Lungs</p> Signup and view all the answers

What are the initial symptoms of whooping cough?

<p>Mild coughing and sneezing (catarrhal)</p> Signup and view all the answers

Which virulence factor of Bordetella pertussis mediates adherence to ciliated epithelial cells?

<p>Fimbriae</p> Signup and view all the answers

What is the main function of pertussis toxin produced by Bordetella pertussis?

<p>Raises cAMP levels</p> Signup and view all the answers

What is the current vaccine for whooping cough called?

<p>Acellular pertussis</p> Signup and view all the answers

What is the recommended method for diagnosing whooping cough?

<p>Nasopharyngeal swab</p> Signup and view all the answers

Which agar is used to culture Bordetella pertussis?

<p>Bordet-Gengou medium</p> Signup and view all the answers

Which of the following is a characteristic of Chlamydophila pneumoniae?

<p>It is an obligate intracellular pathogen.</p> Signup and view all the answers

Which of the following is a characteristic of Mycoplasma?

<p>It attaches to ciliated bronchial epithelial cells.</p> Signup and view all the answers

Which of the following is a characteristic of B. pertussis?

<p>Gram negative coccobacillus</p> Signup and view all the answers

Which of the following is an obligate intracellular pathogen?

<p>Chlamydophila pneumoniae</p> Signup and view all the answers

Which of the following is the recommended method for diagnosing Chlamydophila pneumoniae?

<p>PCR of nasopharyngeal secretions</p> Signup and view all the answers

Which of the following is the most appropriate treatment for Chlamydophila pneumoniae?

<p>Azithromycin</p> Signup and view all the answers

Which of the following is a characteristic of Mycoplasma?

<p>Smallest genome and cell size of a self-replicating organism</p> Signup and view all the answers

Which of the following is a characteristic of Corynebacterium diphtheriae?

<p>Gram positive coccobacillus</p> Signup and view all the answers

Which of the following is a characteristic of Chlamydophila pneumonia regards to transmission?

<p>Person to person transmission by respiratory secretions</p> Signup and view all the answers

Which morphological form of Chlamydophila pneumoniae is the infectious form?

<p>Elementary Body</p> Signup and view all the answers

Where does Chlamydophila pneumoniae replicate?

<p>In an inclusion</p> Signup and view all the answers

Which type of cells does Chlamydophila pneumoniae infect?

<p>Columnar or transitional epithelial cells</p> Signup and view all the answers

Which bacterium is responsible for causing walking pneumonia or atypical pneumonia AND LACKS CELLS WALLS AND PEPTIDOGLYCAN?

<p>Mycoplasma pneumoniae</p> Signup and view all the answers

What is the characteristic symptom of Mycoplasma pneumoniae infection?

<p>Dry hacking cough</p> Signup and view all the answers

Why was Mycoplasma pneumoniae initially thought to be a virus?

<p>It can pass through some filters</p> Signup and view all the answers

Which antibiotic is commonly used to treat Mycoplasma pneumoniae infection?

<p>Azithromycin</p> Signup and view all the answers

What is the morphological form of Chlamydophila pneumoniae that is the intracellular replicative form?

<p>Reticulate Body</p> Signup and view all the answers

Why do Chlamydophila pneumoniae organisms stay in vesicles?

<p>They are protected from the immune system inside vesicles</p> Signup and view all the answers

Which bacteria are extracellular pathogens that secrete ADP-ribosylating toxins?

<p>Pseudomonas, Bordetella, and Corynebacteria</p> Signup and view all the answers

Which bacteria are obligate intracellular pathogens of epithelial cells?

<p>Chlamydia</p> Signup and view all the answers

Which bacteria require sterols to grow and have sterols in their cell membrane and fried egg colonies on culture?

<p>Mycoplasma</p> Signup and view all the answers

Which bacteria cause 'atypical' or 'walking pneumonia'?

<p>Chlamydia and Mycoplasma</p> Signup and view all the answers

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