Dental Diphtheria,Pseudomonas, Pertussis, Chlamydia, Mycoplasma 2023
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Questions and Answers

Which agar is used to culture Corynebacterium diphtheriae?

  • Blood agar
  • Tinsdale agar (correct)
  • MacConkey agar
  • Mannitol salt agar

    • What is the characteristic shape of Corynebacterium diphtheriae?

  • Cocci, arrange themselves in palisades and have club shaped swellings at their poles
  • Spherical, arrange themselves in palisades and have club shaped swellings at their poles
  • Spiral, arrange themselves in palisades and have club shaped swellings at their poles
  • Rod-like, arrange themselves in palisades and have club shaped swellings at their poles (correct)

    • Where does Corynebacterium diphtheriae colonize in the human body?

  • Skin
  • Throat (correct)
  • Lungs
  • Intestines

    • How is Corynebacterium diphtheriae transmitted from one human to another?

    <p>Direct contact</p> Signup and view all the answers

    What can form in the throat due to Corynebacterium diphtheriae infection?

    <p>Pseudomembrane</p> Signup and view all the answers

    What is the vaccine for diphtheria made of?

    <p>Toxoid</p> Signup and view all the answers

    Which strains of Corynebacterium diphtheriae produce the diphtheria toxin?

    <p>Only strains with a beta-phage</p> Signup and view all the answers

    What is the role of the diphtheria toxin in protein synthesis?

    <p>Toxin ADP-ribosylates Elongation Factor 2 (EF2)</p> Signup and view all the answers

    What is a toxoid used in the diphtheria vaccine?

    <p>Formalin-treated toxin</p> Signup and view all the answers

    Which type of bacteria is Corynebacterium diphtheriae?

    <p>Gram positive rod</p> Signup and view all the answers

    Where is Pseudomonas aeruginosa commonly found?

    <p>Water and soil</p> Signup and view all the answers

    What percentage of people have Corynebacterium diphtheriae as normal flora in their gastrointestinal tract?

    <p>10%</p> Signup and view all the answers

    Which term describes Pseudomonas aeruginosa as a pathogen?

    <p>Opportunistic pathogen</p> Signup and view all the answers

    How is Pseudomonas aeruginosa transmitted from one human to another?

    <p>No human to human transmission</p> Signup and view all the answers

    In which population does Pseudomonas aeruginosa chronically colonize the lungs?

    <p>Children with cystic fibrosis</p> Signup and view all the answers

    What can result from Pseudomonas aeruginosa bacteremias and sepsis?

    <p>High mortality</p> Signup and view all the answers

    What is the role of the alginate capsule produced by some strains of Pseudomonas aeruginosa?

    <p>Blocks phagocytosis</p> Signup and view all the answers

    Which factor helps Pseudomonas aeruginosa penetrate deeper into tissues in burn patients?

    <p>Elastase</p> Signup and view all the answers

    What is the characteristic odor produced by Pseudomonas aeruginosa?

    <p>Fruity odor</p> Signup and view all the answers

    What is the role of the pyocyanin pigment produced by Pseudomonas aeruginosa?

    <p>Produces a blue-green pigment</p> Signup and view all the answers

    Which type of bacteria is Pseudomonas aeruginosa?

    <p>Gram negative rod, with polar flagella</p> Signup and view all the answers

    In which population is biofilm formation by Pseudomonas aeruginosa believed to occur?

    <p>Lungs of Cystic fibrosis patients</p> Signup and view all the answers

    What is the function of Pseudomonas Exotoxin A?

    <p>ADP-ribosylates Elongation Factor-2</p> Signup and view all the answers

    Which bacterium causes whooping cough?

    <p>Bordetella pertussis</p> Signup and view all the answers

    What is the main mode of transmission for whooping cough?

    <p>Person to person</p> Signup and view all the answers

    Which organ does Bordetella pertussis colonize in the human body?

    <p>Ciliated epithelium of Lungs</p> Signup and view all the answers

    What are the initial symptoms of whooping cough?

    <p>Mild coughing and sneezing (catarrhal)</p> Signup and view all the answers

    Which virulence factor of Bordetella pertussis mediates adherence to ciliated epithelial cells?

    <p>Fimbriae</p> Signup and view all the answers

    What is the main function of pertussis toxin produced by Bordetella pertussis?

    <p>Raises cAMP levels</p> Signup and view all the answers

    What is the current vaccine for whooping cough called?

    <p>Acellular pertussis</p> Signup and view all the answers

    What is the recommended method for diagnosing whooping cough?

    <p>Nasopharyngeal swab</p> Signup and view all the answers

    Which agar is used to culture Bordetella pertussis?

    <p>Bordet-Gengou medium</p> Signup and view all the answers

    Which of the following is a characteristic of Chlamydophila pneumoniae?

    <p>It is an obligate intracellular pathogen.</p> Signup and view all the answers

    Which of the following is a characteristic of Mycoplasma?

    <p>It attaches to ciliated bronchial epithelial cells.</p> Signup and view all the answers

    Which of the following is a characteristic of B. pertussis?

    <p>Gram negative coccobacillus</p> Signup and view all the answers

    Which of the following is an obligate intracellular pathogen?

    <p>Chlamydophila pneumoniae</p> Signup and view all the answers

    Which of the following is the recommended method for diagnosing Chlamydophila pneumoniae?

    <p>PCR of nasopharyngeal secretions</p> Signup and view all the answers

    Which of the following is the most appropriate treatment for Chlamydophila pneumoniae?

    <p>Azithromycin</p> Signup and view all the answers

    Which of the following is a characteristic of Mycoplasma?

    <p>Smallest genome and cell size of a self-replicating organism</p> Signup and view all the answers

    Which of the following is a characteristic of Corynebacterium diphtheriae?

    <p>Gram positive coccobacillus</p> Signup and view all the answers

    Which of the following is a characteristic of Chlamydophila pneumonia regards to transmission?

    <p>Person to person transmission by respiratory secretions</p> Signup and view all the answers

    Which morphological form of Chlamydophila pneumoniae is the infectious form?

    <p>Elementary Body</p> Signup and view all the answers

    Where does Chlamydophila pneumoniae replicate?

    <p>In an inclusion</p> Signup and view all the answers

    Which type of cells does Chlamydophila pneumoniae infect?

    <p>Columnar or transitional epithelial cells</p> Signup and view all the answers

    Which bacterium is responsible for causing walking pneumonia or atypical pneumonia AND LACKS CELLS WALLS AND PEPTIDOGLYCAN?

    <p>Mycoplasma pneumoniae</p> Signup and view all the answers

    What is the characteristic symptom of Mycoplasma pneumoniae infection?

    <p>Dry hacking cough</p> Signup and view all the answers

    Why was Mycoplasma pneumoniae initially thought to be a virus?

    <p>It can pass through some filters</p> Signup and view all the answers

    Which antibiotic is commonly used to treat Mycoplasma pneumoniae infection?

    <p>Azithromycin</p> Signup and view all the answers

    What is the morphological form of Chlamydophila pneumoniae that is the intracellular replicative form?

    <p>Reticulate Body</p> Signup and view all the answers

    Why do Chlamydophila pneumoniae organisms stay in vesicles?

    <p>They are protected from the immune system inside vesicles</p> Signup and view all the answers

    Which bacteria are extracellular pathogens that secrete ADP-ribosylating toxins?

    <p>Pseudomonas, Bordetella, and Corynebacteria</p> Signup and view all the answers

    Which bacteria are obligate intracellular pathogens of epithelial cells?

    <p>Chlamydia</p> Signup and view all the answers

    Which bacteria require sterols to grow and have sterols in their cell membrane and fried egg colonies on culture?

    <p>Mycoplasma</p> Signup and view all the answers

    Which bacteria cause 'atypical' or 'walking pneumonia'?

    <p>Chlamydia and Mycoplasma</p> Signup and view all the answers

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