Dental Diphtheria,Pseudomonas, Pertussis, Chlamydia, Mycoplasma 2023
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Questions and Answers

Which agar is used to culture Corynebacterium diphtheriae?

  • Blood agar
  • Tinsdale agar (correct)
  • MacConkey agar
  • Mannitol salt agar

What is the characteristic shape of Corynebacterium diphtheriae?

  • Cocci, arrange themselves in palisades and have club shaped swellings at their poles
  • Spherical, arrange themselves in palisades and have club shaped swellings at their poles
  • Spiral, arrange themselves in palisades and have club shaped swellings at their poles
  • Rod-like, arrange themselves in palisades and have club shaped swellings at their poles (correct)

Where does Corynebacterium diphtheriae colonize in the human body?

  • Skin
  • Throat (correct)
  • Lungs
  • Intestines

How is Corynebacterium diphtheriae transmitted from one human to another?

<p>Direct contact (B)</p> Signup and view all the answers

What can form in the throat due to Corynebacterium diphtheriae infection?

<p>Pseudomembrane (C)</p> Signup and view all the answers

What is the vaccine for diphtheria made of?

<p>Toxoid (D)</p> Signup and view all the answers

Which strains of Corynebacterium diphtheriae produce the diphtheria toxin?

<p>Only strains with a beta-phage (A)</p> Signup and view all the answers

What is the role of the diphtheria toxin in protein synthesis?

<p>Toxin ADP-ribosylates Elongation Factor 2 (EF2) (D)</p> Signup and view all the answers

What is a toxoid used in the diphtheria vaccine?

<p>Formalin-treated toxin (D)</p> Signup and view all the answers

Which type of bacteria is Corynebacterium diphtheriae?

<p>Gram positive rod (A)</p> Signup and view all the answers

Where is Pseudomonas aeruginosa commonly found?

<p>Water and soil (D)</p> Signup and view all the answers

What percentage of people have Corynebacterium diphtheriae as normal flora in their gastrointestinal tract?

<p>10% (A)</p> Signup and view all the answers

Which term describes Pseudomonas aeruginosa as a pathogen?

<p>Opportunistic pathogen (C)</p> Signup and view all the answers

How is Pseudomonas aeruginosa transmitted from one human to another?

<p>No human to human transmission (B)</p> Signup and view all the answers

In which population does Pseudomonas aeruginosa chronically colonize the lungs?

<p>Children with cystic fibrosis (C)</p> Signup and view all the answers

What can result from Pseudomonas aeruginosa bacteremias and sepsis?

<p>High mortality (D)</p> Signup and view all the answers

What is the role of the alginate capsule produced by some strains of Pseudomonas aeruginosa?

<p>Blocks phagocytosis (A)</p> Signup and view all the answers

Which factor helps Pseudomonas aeruginosa penetrate deeper into tissues in burn patients?

<p>Elastase (D)</p> Signup and view all the answers

What is the characteristic odor produced by Pseudomonas aeruginosa?

<p>Fruity odor (A)</p> Signup and view all the answers

What is the role of the pyocyanin pigment produced by Pseudomonas aeruginosa?

<p>Produces a blue-green pigment (B)</p> Signup and view all the answers

Which type of bacteria is Pseudomonas aeruginosa?

<p>Gram negative rod, with polar flagella (D)</p> Signup and view all the answers

In which population is biofilm formation by Pseudomonas aeruginosa believed to occur?

<p>Lungs of Cystic fibrosis patients (A)</p> Signup and view all the answers

What is the function of Pseudomonas Exotoxin A?

<p>ADP-ribosylates Elongation Factor-2 (A)</p> Signup and view all the answers

Which bacterium causes whooping cough?

<p>Bordetella pertussis (C)</p> Signup and view all the answers

What is the main mode of transmission for whooping cough?

<p>Person to person (D)</p> Signup and view all the answers

Which organ does Bordetella pertussis colonize in the human body?

<p>Ciliated epithelium of Lungs (D)</p> Signup and view all the answers

What are the initial symptoms of whooping cough?

<p>Mild coughing and sneezing (catarrhal) (A)</p> Signup and view all the answers

Which virulence factor of Bordetella pertussis mediates adherence to ciliated epithelial cells?

<p>Fimbriae (A)</p> Signup and view all the answers

What is the main function of pertussis toxin produced by Bordetella pertussis?

<p>Raises cAMP levels (D)</p> Signup and view all the answers

What is the current vaccine for whooping cough called?

<p>Acellular pertussis (C)</p> Signup and view all the answers

What is the recommended method for diagnosing whooping cough?

<p>Nasopharyngeal swab (A)</p> Signup and view all the answers

Which agar is used to culture Bordetella pertussis?

<p>Bordet-Gengou medium (A)</p> Signup and view all the answers

Which of the following is a characteristic of Chlamydophila pneumoniae?

<p>It is an obligate intracellular pathogen. (D)</p> Signup and view all the answers

Which of the following is a characteristic of Mycoplasma?

<p>It attaches to ciliated bronchial epithelial cells. (A)</p> Signup and view all the answers

Which of the following is a characteristic of B. pertussis?

<p>Gram negative coccobacillus (B)</p> Signup and view all the answers

Which of the following is an obligate intracellular pathogen?

<p>Chlamydophila pneumoniae (D)</p> Signup and view all the answers

Which of the following is the recommended method for diagnosing Chlamydophila pneumoniae?

<p>PCR of nasopharyngeal secretions (D)</p> Signup and view all the answers

Which of the following is the most appropriate treatment for Chlamydophila pneumoniae?

<p>Azithromycin (B)</p> Signup and view all the answers

Which of the following is a characteristic of Mycoplasma?

<p>Smallest genome and cell size of a self-replicating organism (A)</p> Signup and view all the answers

Which of the following is a characteristic of Corynebacterium diphtheriae?

<p>Gram positive coccobacillus (D)</p> Signup and view all the answers

Which of the following is a characteristic of Chlamydophila pneumonia regards to transmission?

<p>Person to person transmission by respiratory secretions (C)</p> Signup and view all the answers

Which morphological form of Chlamydophila pneumoniae is the infectious form?

<p>Elementary Body (A)</p> Signup and view all the answers

Where does Chlamydophila pneumoniae replicate?

<p>In an inclusion (B)</p> Signup and view all the answers

Which type of cells does Chlamydophila pneumoniae infect?

<p>Columnar or transitional epithelial cells (A)</p> Signup and view all the answers

Which bacterium is responsible for causing walking pneumonia or atypical pneumonia AND LACKS CELLS WALLS AND PEPTIDOGLYCAN?

<p>Mycoplasma pneumoniae (B)</p> Signup and view all the answers

What is the characteristic symptom of Mycoplasma pneumoniae infection?

<p>Dry hacking cough (B)</p> Signup and view all the answers

Why was Mycoplasma pneumoniae initially thought to be a virus?

<p>It can pass through some filters (C)</p> Signup and view all the answers

Which antibiotic is commonly used to treat Mycoplasma pneumoniae infection?

<p>Azithromycin (A)</p> Signup and view all the answers

What is the morphological form of Chlamydophila pneumoniae that is the intracellular replicative form?

<p>Reticulate Body (D)</p> Signup and view all the answers

Why do Chlamydophila pneumoniae organisms stay in vesicles?

<p>They are protected from the immune system inside vesicles (B)</p> Signup and view all the answers

Which bacteria are extracellular pathogens that secrete ADP-ribosylating toxins?

<p>Pseudomonas, Bordetella, and Corynebacteria (B)</p> Signup and view all the answers

Which bacteria are obligate intracellular pathogens of epithelial cells?

<p>Chlamydia (B)</p> Signup and view all the answers

Which bacteria require sterols to grow and have sterols in their cell membrane and fried egg colonies on culture?

<p>Mycoplasma (D)</p> Signup and view all the answers

Which bacteria cause 'atypical' or 'walking pneumonia'?

<p>Chlamydia and Mycoplasma (A)</p> Signup and view all the answers

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