10 Questions
What is the phenomenon called when only one X chromosome is functioning in a mammalian somatic cell?
X chromosome inactivation
What is the structure of the inactive X chromosome during most of the cell cycle?
Heterochromatin
What is the mechanism that converges in inactivating an X chromosome across mammalian groups?
Methylation of promoters
What is the name of the locus on the X chromosome that is transcribed on the inactive X chromosome?
XIST
What happens to the promoter regions of genes on the inactive X chromosome in humans?
They are methylated
What is the product of the XIST locus gene?
An untranslated RNA molecule
When does the inactive X chromosome replicate in the cell cycle?
Later than most chromatin
What is the result of X chromosome inactivation in mammalian somatic cells?
One functioning X chromosome
What is the significance of XIST RNA coating the inactive X chromosome?
It remodels the chromatin
Which of the following is a characteristic of the inactive X chromosome?
It is highly condensed
Learn how cells with the same genome differentiate into various cell types. This quiz explores the role of histones, nucleosomes, and chromatin structure in gene expression and cell specialization.
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