Diabetes Pathophysiology Quiz1
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Questions and Answers

What is the primary defect in Type 1 Diabetes Mellitus?

  • Increased insulin secretion (correct)
  • Glucagon excess (correct)
  • Insulin resistance (correct)
  • Absolute insulin deficiency due to beta-cell destruction (correct)
  • Which of the following is most commonly associated with Type 2 Diabetes Mellitus?

  • Ketosis-prone diabetes (correct)
  • Pancreatitis
  • Autoimmune destruction of beta cells (correct)
  • Peripheral insulin resistance (correct)
  • What is the primary metabolic complication of untreated Type 1 Diabetes?

  • Hyperosmolar hyperglycemic state (correct)
  • Diabetic ketoacidosis (correct)
  • Lactic acidosis (correct)
  • Hypoglycemia (correct)
  • Which of the following is a common risk factor for the development of Type 2 Diabetes?

    <p>Hypothyroidism</p> Signup and view all the answers

    Which laboratory test is used to monitor long-term glycemic control in diabetic patients?

    <p>Fasting blood glucose</p> Signup and view all the answers

    Which of the following is an acute complication of Type 2 Diabetes Mellitus?

    <p>Diabetic ketoacidosis</p> Signup and view all the answers

    What percentage of cases does Type 1 Diabetes account for among all diabetes cases?

    <p>10%</p> Signup and view all the answers

    Which of the following is a characteristic feature of Type 2 Diabetes?

    <p>Rapid onset</p> Signup and view all the answers

    Which of the following is a primary environmental factor contributing to Type 2 Diabetes?

    <p>Poor dietary habits</p> Signup and view all the answers

    Which of the following autoantibodies is commonly associated with Type 1 Diabetes?

    <p>Anti-glutamic acid decarboxylase (Anti-GAD)</p> Signup and view all the answers

    Which of the following conditions is most likely to lead to the development of Type 1 Diabetes?

    <p>Chronic pancreatitis</p> Signup and view all the answers

    Which of the following is a common microvascular complication of Diabetes Mellitus?

    <p>Retinopathy</p> Signup and view all the answers

    Which of the following is NOT a typical symptom of hyperglycemia?

    <p>Polyuria</p> Signup and view all the answers

    Which of the following is the first line of treatment for Type 2 Diabetes in obese patients?

    <p>Metformin</p> Signup and view all the answers

    Which of the following is a risk factor specific to gestational diabetes?

    <p>History of large-for-gestational-age infant</p> Signup and view all the answers

    Which test confirms the diagnosis of gestational diabetes?

    <p>Fasting glucose test</p> Signup and view all the answers

    What is the main goal of diabetes management?

    <p>To eliminate carbohydrate intake</p> Signup and view all the answers

    Which of the following lifestyle changes is recommended for managing Type 2 Diabetes?

    <p>Increased carbohydrate intake</p> Signup and view all the answers

    Which of the following symptoms is more specific to Type 1 Diabetes?

    <p>Ketosis/ketonuria</p> Signup and view all the answers

    What is the primary goal of treatment in diabetes management?

    <p>Reduction of hyperglycemia</p> Signup and view all the answers

    What are the main features that distinguish Type 1 Diabetes from Type 2 Diabetes?

    <p>Type 1 Diabetes is characterized by an absolute insulin deficiency due to autoimmune destruction of pancreatic beta cells, often presenting in younger individuals, while Type 2 Diabetes is characterized by insulin resistance and relative insulin deficiency, commonly associated with obesity and occurring later in life.</p> Signup and view all the answers

    Explain the role of HbA1c in the management of diabetes.

    <p>HbA1c reflects the average blood glucose levels over the past 2-3 months and is used to assess long-term glycemic control and adjust therapy accordingly.</p> Signup and view all the answers

    What is the significance of ketosis in Type 1 Diabetes?

    <p>Ketosis in Type 1 Diabetes indicates a lack of insulin, leading to fat breakdown and the production of ketones, which can result in diabetic ketoacidosis, a potentially life-threatening condition.</p> Signup and view all the answers

    Describe the primary treatment approach for a newly diagnosed patient with Type 2 Diabetes who is overweight.

    <p>The primary treatment approach involves lifestyle modifications such as diet and exercise to promote weight loss, along with metformin as first-line pharmacotherapy to improve insulin sensitivity.</p> Signup and view all the answers

    Study Notes

    Type 1 Diabetes Mellitus

    • Characterized by absolute insulin deficiency due to autoimmune destruction of pancreatic beta cells.
    • Accounts for approximately 10% of all diabetes cases.
    • Presents primarily in younger individuals and can lead to complications like diabetic ketoacidosis.

    Type 2 Diabetes Mellitus

    • Associated with peripheral insulin resistance and relative insulin deficiency.
    • Often linked to obesity and a sedentary lifestyle, which contributes to its development.
    • May be asymptomatic in the early stages and is more common in adults.

    Key Complications

    • Diabetic ketoacidosis is the primary metabolic complication of untreated Type 1 Diabetes.
    • Acute complications include hyperosmolar hyperglycemic state in Type 2 Diabetes Mellitus.
    • Common microvascular complications include retinopathy, nephropathy, and neuropathy.

    Laboratory Testing

    • HbA1c is the key laboratory test for monitoring long-term glycemic control, reflecting average glucose levels over 2-3 months.
    • The Oral Glucose Tolerance Test (OGTT) is essential for diagnosing gestational diabetes.

    Treatment Approaches

    • First-line treatment for Type 2 Diabetes in obese patients includes lifestyle changes (diet and physical activity) along with metformin.
    • Diabetic management targets achieving normal blood glucose levels and reducing hyperglycemia.

    Risk Factors

    • Sedentary lifestyle and poor dietary habits are significant risk factors for developing Type 2 Diabetes.
    • Gestational diabetes risk factors include a history of large-for-gestational-age infants, obesity, and advanced maternal age.

    Distinctions between Types

    • Type 1 Diabetes features ketosis and requires insulin therapy from diagnosis.
    • Type 2 Diabetes typically develops with insulin resistance and does not necessarily lead to ketosis.

    Symptoms and Management

    • Symptoms of hyperglycemia include polyuria, polydipsia, and blurred vision; weight gain is not typical.
    • Regular physical activity is crucial in managing Type 2 Diabetes and improving insulin sensitivity.

    Autoantibodies

    • Anti-glutamic acid decarboxylase (Anti-GAD) autoantibodies are commonly associated with Type 1 Diabetes.

    Overall Goals of Diabetes Management

    • The primary goal is to reduce hyperglycemia and achieve optimal blood glucose levels to prevent complications and enhance quality of life.

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    Related Documents

    QQuiz 1.docx

    Description

    Test your knowledge on the pathophysiology of Type 1 and Type 2 Diabetes Mellitus in this quiz. Explore the differences in insulin production, resistance, and associated conditions through multiple-choice questions. Perfect for students and healthcare professionals looking to reinforce their understanding of diabetes.

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