Podcast
Questions and Answers
What is the percentage of patients with the potential risk of developing the disease due to the combination of DR3+DR4 antigens?
What is the percentage of patients with the potential risk of developing the disease due to the combination of DR3+DR4 antigens?
- 85%
- 95% (correct)
- 75%
- 90%
What is the primary mechanism of B-cell death in autoimmune insulitis?
What is the primary mechanism of B-cell death in autoimmune insulitis?
- Necrosis
- Autophagy
- Apoptosis (correct)
- Mitosis
What is the main link in the pathogenesis of type 1 diabetes mellitus?
What is the main link in the pathogenesis of type 1 diabetes mellitus?
- Dysfunction of the other islet cell types
- Defect in the immunological surveillance system
- Inflammation in the islets of Langerhans (correct)
- Genetic predisposition to autoimmune diseases
Which of the following genes are associated with type 1 diabetes mellitus?
Which of the following genes are associated with type 1 diabetes mellitus?
What is the role of T lymphocytes in the development of type 1 diabetes mellitus?
What is the role of T lymphocytes in the development of type 1 diabetes mellitus?
What is the normal ratio of insulin and C-peptide concentrations in blood and urine?
What is the normal ratio of insulin and C-peptide concentrations in blood and urine?
What is the primary characteristic of diabetes mellitus?
What is the primary characteristic of diabetes mellitus?
Which of the following organs are particularly affected by chronic hyperglycaemia?
Which of the following organs are particularly affected by chronic hyperglycaemia?
What is the primary cause of Type 1 diabetes mellitus?
What is the primary cause of Type 1 diabetes mellitus?
What is the term for the destruction of B-cells leading to absolute insulin deficiency?
What is the term for the destruction of B-cells leading to absolute insulin deficiency?
What is the term for the acute life-threatening complication of diabetes characterized by hyperglycaemia and dehydration?
What is the term for the acute life-threatening complication of diabetes characterized by hyperglycaemia and dehydration?
How many groups of diabetes mellitus are distinguished by the modern classification of diabetes mellitus?
How many groups of diabetes mellitus are distinguished by the modern classification of diabetes mellitus?