12 Questions
What is the percentage of patients with the potential risk of developing the disease due to the combination of DR3+DR4 antigens?
95%
What is the primary mechanism of B-cell death in autoimmune insulitis?
Apoptosis
What is the main link in the pathogenesis of type 1 diabetes mellitus?
Inflammation in the islets of Langerhans
Which of the following genes are associated with type 1 diabetes mellitus?
HLA genes B8 and B15
What is the role of T lymphocytes in the development of type 1 diabetes mellitus?
Initiation and development of the autoimmune process
What is the normal ratio of insulin and C-peptide concentrations in blood and urine?
1/3
What is the primary characteristic of diabetes mellitus?
Hyperglycaemia due to insulin deficiency or impaired interaction
Which of the following organs are particularly affected by chronic hyperglycaemia?
Eyes, kidneys, nervous system, and cardiovascular system
What is the primary cause of Type 1 diabetes mellitus?
Absolute deficit in insulin secretion
What is the term for the destruction of B-cells leading to absolute insulin deficiency?
Immune-mediated diabetes
What is the term for the acute life-threatening complication of diabetes characterized by hyperglycaemia and dehydration?
Hyperosmolar coma without ketoacidosis
How many groups of diabetes mellitus are distinguished by the modern classification of diabetes mellitus?
4
Test your knowledge about diabetes mellitus, a group of metabolic diseases characterized by hyperglycaemia. Learn about the effects of chronic hyperglycaemia on various organs and the symptoms associated with the disease. Evaluate your understanding of the disease and its implications.
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