32 Diabetes and Necrotizing Otitis Externa Quiz
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Questions and Answers

What is the most common organism associated with Necrotizing Otitis Externa?

  • Streptococcus pneumoniae
  • Haemophilus influenzae
  • Staphylococcus aureus
  • Pseudomonas aeruginosa (correct)
  • Which of the following may be a complication of Necrotizing Otitis Externa?

  • Facial nerve damage (correct)
  • Nosebleed
  • Hearing loss only
  • Mild ear pain
  • Which of the following is NOT a clinical feature of Necrotizing Otitis Externa?

  • Headache
  • Discharge with foul odor
  • Persistent ear ache, particularly at night
  • Migraine headaches (correct)
  • In terms of treatment for Necrotizing Otitis Externa, what is the most appropriate course of action?

    <p>Systemic antibiotics and local therapy (A)</p> Signup and view all the answers

    Based on the provided content, what percentage of Necrotizing Otitis Externa cases occur in diabetic patients?

    <p>90% (D)</p> Signup and view all the answers

    What percentage of infection-related hospitalizations are associated with type 1 and type 2 diabetes mellitus?

    <p>6% (B)</p> Signup and view all the answers

    What is the most prevalent type of diabetes mellitus in Ireland?

    <p>Type 2 diabetes mellitus (B)</p> Signup and view all the answers

    What is the defining manifestation of diabetes mellitus?

    <p>Hyperglycemia (B)</p> Signup and view all the answers

    What is the mechanism behind type 1 diabetes mellitus?

    <p>Autoimmune destruction of insulin-secreting cells (D)</p> Signup and view all the answers

    What is the average age of diagnosis for type 2 diabetes mellitus in Ireland?

    <p>5th to 6th decade of life (B)</p> Signup and view all the answers

    Which of the following is NOT a common infection associated with diabetes mellitus?

    <p>Hepatitis C (D)</p> Signup and view all the answers

    What is a key characteristic of infections in people with diabetes mellitus?

    <p>They progress more rapidly to severe forms. (B)</p> Signup and view all the answers

    What is good evidence that can improve outcomes in people with diabetes mellitus?

    <p>Reduction of hyperglycemia (D)</p> Signup and view all the answers

    In diabetic patients, what can lead to a weakened immune system and increased risk of infections?

    <p>All of the above (D)</p> Signup and view all the answers

    What key element of foot ulcer prevention focuses on educating individuals involved in the patient's care?

    <p>Educating the patient, family and healthcare professionals (D)</p> Signup and view all the answers

    Which of the following is NOT a suggested medical intervention to prevent foot ulcers in diabetic patients?

    <p>Administering antibiotics prophylactically (C)</p> Signup and view all the answers

    Which study suggests a potential beneficial effect of insulin on the immune system in diabetic patients?

    <p>A study that found T cells lacking insulin receptors are impaired in diabetic patients. (C)</p> Signup and view all the answers

    What is the main reason why diabetic patients should get vaccinated against infections like COVID-19, influenza, and S. pneumoniae?

    <p>These infections can be more severe in people with diabetes. (E)</p> Signup and view all the answers

    Which areas of the foot are considered highest risk for ulceration?

    <p>The heel and plantar aspect (sole) of the foot (A)</p> Signup and view all the answers

    What does the acronym IWGDF stand for in the context of foot ulcer prevention?

    <p>International Working Group on Diabetic Foot (A)</p> Signup and view all the answers

    What does the term 'offloading' refer to in the context of foot wound care?

    <p>Removing pressure from the wound to promote healing (B)</p> Signup and view all the answers

    Which organism is NOT commonly associated with cellulitis in diabetic patients?

    <p>Pseudomonas (B)</p> Signup and view all the answers

    What is a key treatment component for Fournier Gangrene?

    <p>Debridement (B)</p> Signup and view all the answers

    Which symptom is most characteristic of Necrotising Fasciitis?

    <p>Purplish rash (C)</p> Signup and view all the answers

    For empiric treatment of cellulitis, what antibiotic is commonly started?

    <p>Flucloxacillin (A)</p> Signup and view all the answers

    Which of the following is a clinical feature of Fournier Gangrene?

    <p>Fever and dizziness (A)</p> Signup and view all the answers

    What antibiotic combination is recommended if group A strep is suspected?

    <p>Benzylpenicillin and clindamycin (B)</p> Signup and view all the answers

    Which clinical feature is NOT associated with rapidly progressive necrotizing fasciitis?

    <p>Dark urine (C)</p> Signup and view all the answers

    Which organism is most commonly associated with emphysematous cholecystitis?

    <p>Clostridium perfringens (B)</p> Signup and view all the answers

    What complication is least associated with chronic hepatitis C infection in type 2 diabetes patients?

    <p>Acute kidney injury (D)</p> Signup and view all the answers

    What is a notable clinical feature of both emphysematous cholecystitis and hepatitis?

    <p>Abdominal pain (A)</p> Signup and view all the answers

    Which statement about the treatment of mild emphysematous cholecystitis is correct?

    <p>Antibiotics can be trialed in mild cases. (B)</p> Signup and view all the answers

    How does chronic hepatitis C infection impact type 2 diabetes outcomes?

    <p>Worsens outcomes with cirrhosis increase. (B)</p> Signup and view all the answers

    What symptom would be least likely reported by a patient with emphysematous cholecystitis?

    <p>Dry cough (A)</p> Signup and view all the answers

    What is the recommended action regarding specimen collection in diabetic foot infections before starting antimicrobial therapy?

    <p>Obtain specimens ideally before starting antimicrobial therapy. (A)</p> Signup and view all the answers

    Which specimen collection method is acceptable for diagnosing osteomyelitis?

    <p>Tissue specimen from the base of a debrided ulcer. (D)</p> Signup and view all the answers

    What is the best practice for urine sample collection when a delay of ≥4 hours is expected before laboratory transport?

    <p>Use a urine container with boric acid. (C)</p> Signup and view all the answers

    In the clinical diagnosis of diabetic foot infections, which of the following is NOT a symptom or sign of inflammation to look for?

    <p>Increased hair growth around the wound. (C)</p> Signup and view all the answers

    What should be included when sending specimens to microbiology for a diabetic foot infection?

    <p>Clinical details that the specimen is from a diabetic foot infection. (D)</p> Signup and view all the answers

    Which approach is advised for starting empirical antimicrobial therapy for diabetic foot infections?

    <p>Consult local hospital guidelines before initiating therapy. (A)</p> Signup and view all the answers

    Which of the following describes the Probe to Bone test in relation to diabetic foot infections?

    <p>It aids in the diagnosis but results must be interpreted in context. (B)</p> Signup and view all the answers

    What is the gold standard method for diagnosing bone involvement in diabetic foot infections?

    <p>Bone biopsy. (B)</p> Signup and view all the answers

    Flashcards

    Diabetes Mellitus

    A condition where the body cannot regulate blood sugar levels properly due to inadequate insulin action.

    Type 1 Diabetes Mellitus

    Type of diabetes where the immune system mistakenly attacks and destroys insulin-producing cells in the pancreas, leading to a complete lack of insulin.

    Type 2 Diabetes Mellitus

    Type of diabetes caused by the body's inability to use insulin effectively, resulting in a relative deficiency.

    Hyperglycemia

    Elevated blood sugar levels.

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    Diabetes and Infection

    Diabetes increases the risk of infections, including bone and joint infections, sepsis and cellulitis.

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    Infections in Diabetes: Impact

    Infections are more frequent, respond poorly to treatment and progress rapidly to severe forms in individuals with diabetes.

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    Hyperglycemia Management: Impact on Infections

    Reducing high blood sugar levels in diabetes can improve overall outcomes.

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    Diabetes Mellitus: Risk of Infection

    Individuals with diabetes mellitus are at a significantly higher risk of infections, with infections contributing to a considerable portion of hospitalizations and deaths.

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    Cellulitis

    A bacterial infection of the skin that is characterized by redness, swelling, pain, warmth, tenderness to the touch, and possibly fever.

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    Fournier Gangrene

    A serious infection of the soft tissue and fascia, often caused by multiple bacteria, including Staph aureus and Pseudomonas.

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    Necrotizing Fasciitis

    A rare, severe infection that spreads rapidly and can lead to tissue death and limb loss, often caused by Group A Streptococcus (Streptococcus pyogenes) and other bacteria.

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    Wound Infection

    A common bacterial infection of the skin that causes a red, swollen, and painful area of skin that is warm and tender to the touch

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    IV Vancomycin

    Drug used to treat MRSA infections.

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    Necrotizing Otitis Externa

    A serious ear infection that primarily affects individuals with diabetes mellitus, characterized by deep-seated ear pain, foul-smelling discharge, and a risk of complications extending beyond the ear.

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    Pseudomonas aeruginosa

    The bacteria most commonly responsible for Necrotizing Otitis Externa.

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    Invasion of Surrounding Structures

    A severe complication of Necrotizing Otitis Externa where the infection spreads beyond the ear to nearby structures like the facial nerve or skull base.

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    Intracranial Involvement

    A complication of Necrotizing Otitis Externa potentially leading to confusion, meningitis, blood clots, and even death due to the infection spreading to the brain.

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    Treatment for Necrotizing Otitis Externa

    The recommended treatment for Necrotizing Otitis Externa, involving antibiotics that target Pseudomonas aeruginosa and local care to clean and remove infected tissue.

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    Healthy Diet and Immunity

    Maintaining a balanced diet rich in fruits, vegetables, and whole grains can help strengthen the body's defense system and reduce the chances of getting sick.

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    Foot Self-Examination

    Regularly checking your feet for any cuts, sores, or changes in color or temperature can help prevent infections.

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    Proper Footwear

    Wearing shoes that fit well and provide good support can help prevent foot injuries and ulcers.

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    Importance of Podiatrists

    A podiatrist is a foot specialist who can provide expert care and advice to help prevent foot problems.

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    Wound Care

    Prompt and appropriate treatment of wounds can help prevent infection and complications.

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    Glucose Control

    Controlling blood sugar levels is crucial for preventing infections and complications in people with diabetes.

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    Managing Co-Existing Medical Conditions

    Managing existing conditions like heart disease or high blood pressure can also help reduce the risk of foot infections.

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    Vaccines for Diabetes

    Getting vaccinated against infections such as COVID-19, influenza, and pneumonia can help protect against serious illnesses.

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    Necrotizing fasciitis caused by group A Streptococcus

    A common bacterial infection responsible for necrotizing fasciitis, particularly affecting the genitals and surrounding areas. It's often treated with a combination of antibiotics, including vancomycin, piperacillin-tazobactam, and clindamycin.

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    Antibiotic treatment for group A Streptococcus necrotizing fasciitis

    A combination of antibiotics commonly used to treat necrotizing fasciitis caused by group A Streptococcus. This regimen includes benzylpenicillin and clindamycin, the latter suppressing toxin production by the bacteria.

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    Hepatitis in Diabetes

    Inflammation of the liver, often associated with diabetes. It's more common in individuals with type 2 diabetes and can complicate the course of hepatitis C infection.

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    Non-alcoholic fatty liver disease (NAFLD)

    A condition characterized by the accumulation of fat in the liver, often associated with type 2 diabetes. It's more common in individuals with this type of diabetes.

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    Emphysematous Cholecystitis

    A rare and life-threatening inflammatory condition of the gallbladder, often associated with diabetes. It's characterized by gas formation within the gallbladder wall and is commonly caused by bacteria like Clostridium perfringens, Klebsiella, and E. coli.

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    Complications of Emphysematous Cholecystitis

    An infection of the gallbladder that can progress to serious complications such as acute kidney injury, septic shock, and rarely, pneumnomediastinum. It's often treated with surgery, but antibiotics may be considered for mild cases.

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    Clinical features of Emphysematous Cholecystitis

    A condition affecting the gallbladder, often associated with diabetes, characterized by nonspecific symptoms like fever, abdominal pain, and nausea and vomiting.

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    Probe to bone test

    A test used to help diagnose osteomyelitis in diabetic foot infections. It involves probing the bone to see if there is any pus or drainage, which could indicate an infection.

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    Midstream urine collection

    A type of urine collection where the first few milliliters of urine are discarded, followed by collecting the midstream portion of the sample. This technique reduces contamination from the urethra and provides a more accurate urine sample.

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    Urine container with boric acid

    A container for collecting urine samples that contains boric acid, which inhibits bacterial growth. It helps preserve the sample and ensures accurate test results, especially when there's a delay in delivering the sample to the lab.

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    Tissue specimen for diabetic foot infection

    Tissue samples taken from the base of a debrided wound, often obtained by a podiatrist, are the most reliable samples for identifying the specific bacteria causing an infection in a diabetic foot. Superficial swabs tend to pick up colonizing bacteria, which may not be the primary cause of the infection, hence they are less accurate.

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    Specimen collection and sensitivity testing

    Sending specimens for culture and sensitivity testing is crucial to identify the specific bacteria causing an infection and determine the most effective antibiotics. It's essential to obtain and send these specimens before starting antimicrobial therapy to ensure that the chosen antibiotics are effective against the specific bacteria involved.

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    Clinical assessment of diabetic foot infection

    Clinical assessment of a diabetic foot infection involves evaluating systemic signs in the patient, risk factors in the affected limb, and local signs of inflammation in the wound. It helps determine the severity of the infection and guides treatment.

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    Classic symptoms of diabetic foot infection

    Classic symptoms of infection include redness, swelling, pain, warmth, and pus. At least two of these signs are typically present in a diabetic foot infection, indicating inflammation or purulence, supporting the diagnosis of infection.

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    Choosing appropriate antibiotics for diabetic foot infection

    The choice of antibiotics depends on the severity of the infection, the location of the infection, and the type of bacteria suspected. Consulting local hospital guidelines and considering the patient's risk factors and allergies is important.

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    Study Notes

    Infections in People with Diabetes Mellitus

    •  Infections are more frequent, and individuals with diabetes mellitus have a poorer response to treatment leading to a more rapid progression to severe forms of infection.

    •  Type 1 and type 2 Diabetes Mellitus are associated with a high risk of infection.

    •  6% of infection-related hospitalizations and 12% of infection-related deaths are linked to diabetes.

    •  Strongest associations with bone and joint infections, sepsis, and cellulitis.

    Diabetes Mellitus

    •  Diabetes mellitus is characterized by inadequate insulin action, leading to hyperglycemia.

    •  Type 1 diabetes mellitus is the result of autoimmune destruction of insulin-secreting cells, leading to an absolute deficiency of insulin.

    •  Type 2 diabetes mellitus is characterized by relative inadequacy of insulin action due to end-organ insulin resistance.

    •  In Ireland, 87.9% of diabetics have type 2 diabetes

    •  The average age of diagnosis for type 2 diabetes is between the 5th and 6th decade of life.

    •  Often, individuals with Type 2 Diabetes are asymptomatic.

    Urinary Tract Infections (UTIs) in Diabetes

    •  Women with diabetes are almost twice more likely to experience UTIs than those without.

    •  Essential to conduct urine culture to diagnose UTIs.

    •  Do not treat asymptomatic bacteriuria.

    •  Treatment decisions should be based on local trends of antibiotic resistance.

    •  Complications include: incontinence, chronic prostatitis, staghorn urinary calculi, and pyelonephritis.

    •  Patients with DM have a higher risk of progression to bilateral pyelonephritis which is often more severe.

    Pneumonia in Diabetes

    •  Patients with DM have higher rates of hospitalization and mortality with pneumonia.

    •  The most common organisms affecting individuals with diabetes are Streptococcus species (community-acquired) and Gram-negative anaerobes (aspiration pneumonia).

    •  For community-acquired pneumonia, calculate CURB-65 to determine appropriate antibiotic treatment.

    •  For healthcare-acquired pneumonia, antibiotic decisions should be guided by local antibiotic resistance trends.

    Pneumonia: Clinical Features and Complications

    •  Clinical features include a productive cough (mucopurulent sputum), shortness of breath, pleuritic chest pain, fatigue, malaise, and fever.

    •  Complications may include empyema, pericarditis, respiratory failure, diabetic ketoacidosis, and sepsis.

    Tuberculosis in Diabetes

    •  Patients with poorer glycaemic control have a higher risk of contracting tuberculosis.

    •  Patients with DM are also at higher risk of treatment failure in tuberculosis.

    •  Isoniazid is best taken with pyridoxine.

    •  Rifampin may cause hyperglycemia and increase the clearance of diabetic medications.

    COVID-19 in Diabetes

    •  Diabetes is correlated with an increased risk of COVID-19 morbidity and mortality.

    •  Poorly-controlled diabetes is significantly correlated with increased mortality in both type 1 and type 2 diabetics.

    Skin and Soft Tissue Infections (SSTIs) in Diabetes

    •  The most common organisms causing SSTIs in diabetes are Staph aureus, S. pyogenes and other streptococcal species.

    •  Empiric treatment (flucloxacillin for superficial ulcers and Co-amoxiclav/piperacillin-tazobactam for deep ulcers for example) is commonly used with adjustments based on specific cultures and susceptibilities.

    Fournier Gangrene

    •  Anaerobic and aerobic bacteria, such as Staph aureus, Pseudomonas, and Clostridium perfringens are the common causative organisms for Fournier Gangrene.

    •  Debridement and broad-spectrum antibiotics are essential for treatment.

    •  Clinical features include infection of soft tissue and fascia, pain, fever, diarrhoea, dizziness, swelling, and a purplish rash.

    •  Necrosis and edema are frequently noted in the condition.

    Necrotizing Fasciitis

    •  Severe infection, limb loss is more common with this condition.

    •  Group A Strep (Streptococcus pyogenes), often with other contributing organisms is typically the causative factor.

    •  Treatment involves surgical debridement.

    •  Empiric therapy with broad-spectrum antibiotics, targeting, for instance, vancomycin alongside piperacillin-tazobactam and clindamycin, is often administered.

    Hepatitis in Diabetes

    •  Hepatitis C outcomes in individuals with type 2 diabetes are worse than in those without, with higher instances of cirrhosis and antiviral treatment failure.

    •  Chronic Hepatitis C is found significantly more in those with Type 2 Diabetes (T2DM)

    •  Chronic Hepatitis C sufferers with T2DM are more likely to suffer from cirrhosis.

    •  Clinical features include abdominal pain, nausea and vomiting, weakness and fatigue, and dark urine.

    •  Complications of Hepatitis C in diabetics include cirrhosis, malignancy, and fulminant liver failure.

    Emphysematous Cholecystitis

    •  Approximately 50% of those with emphysematous cholecystitis have diabetes.

    •  The most common causative organisms are Clostridium perfringens, Klebsiella, and E. coli.

    •  Treatment is typically cholecystectomy; however, antibiotics may be considered in mild cases.

    •  Clinical features include nonspecific symptoms, fever, abdominal pain, and nausea/vomiting.

    •  Complications can include acute kidney injury (AKI), septic shock, and rarely, pneumomediastinum.

    Necrotizing Otitis Externa

    •  Necrotizing otitis externa is 90% correlated with diabetes.

    •  The frequently identified pathogenic organism is Pseudomonas aeruginosa.

    •  Treatment involves systemic antibiotics with antipseudomonal activity in conjunction with local canal care, including cleaning and debridement.

    •  Clinical features include constant severe localized ear pain (typically worse at night), a foul-smelling purulent otorrhoea, headaches, and invasion of surrounding structures like the facial nerve, leading potentially to complications such as skull base osteomyelitis, intracranial involvement (leading to confusion,meningitis, or thrombosis), and death.

    Onychomycosis

    • Individuals with diabetes are twice as likely to develop onychomycosis.

    •  Onychomycosis is fungal infection affecting the toenails or fingernails.

    •  Diagnosis is via fungal culture and microscopy.

    •  Treatment typically involves oral antifungal agents.

    •  Clinical features include discolouration, subungal hyperkeratosis, onycholysis, and nail plate destruction.

    •  Complications include functional impairment and chronic pain.

    Mucormycosis

    •  Mucormycosis is strongly associated with diabetes, with between 17% and 88% of cases occurring in individuals with DM.

    •  This infection is caused by various species of mucormycetes.

    •  A tissue biopsy is necessary for diagnosis, and imaging can assist in assessing the infection's extent.

    •  Debulking of infected areas plus antifungal therapy is essential as a treatment strategy.

    •  Clinical presentation typically includes acute sinusitis/headache, respiratory issues, and skin lesions.

    •  Sinuses are commonly involved in primary infections, with the cerebrum/orbits also being frequently affected early.

    •  The respiratory tract is a common secondary infection site and is often indicated by fever and haemoptysis.

    •  Skin infections are typically indicated by single, ulcerative, necrotic lesions accompanied by pain and inflammation.

    •  Further issues including lower abdominal pain and haematemesis may also manifest depending on the region and extent of infection.

    Fungal Genitourinary Infections

    •  Risk of fungal genitourinary infections is heightened by the use of SGLT2 inhibitors and increased glucose concentration in urine.

    •  Candida species are frequently seen as the causative organism in these infections.

    •  Early treatment with fluconazole is a common first-line approach for symptomatic treatment.

    •  Complications include recurrence and candidaemia, particularly in immunocompromised patients.

    Laboratory Diagnosis of Infections in Diabetes

    •  Laboratory diagnosis should be detailed.  Specific procedures should be conducted depending on the area of infection and the patient's history.

    Foot Infections in Diabetes

    •  Important to send appropriately obtained specimens to the Microbiology lab. Ideally this occurs before antibiotic treatment.

    •  Cleanse and debride the infected area before collecting wound samples.

    •  Collecting a sample from the base of the ulcer is the preferred technique rather than a superficial swab.

    •  The specimen is usually placed in saline and sent promptly to the lab.

    •  Essential to provide a detailed history for the specimen which emphasizes the causative factor is a diabetic foot infection, as well as details surrounding a Gram stain, culture and susceptibility testing.

    Investigating Diabetic Foot Infections

    •  Blood cultures and other relevant cultures (urine, tissue, or bone) should be conducted, as well as a MRSA screen

    •  History of residential care and recent hospitalisation are relevant factors that should raise caution and suspicion.

    •  In cases of suspected osteomyelitis, imaging like CXR and X-rays of affected areas, or in cases where osteomyelitis isn't evident, MRI is commonly used when required.

    •  Vascular assessment is important and should include ankle brachial index, Doppler waveform, or transcutaneous oxygen tension determination, where feasible.  Toe pressures are also commonly considered.

    •  Results obtained from these procedures should be viewed against the broader clinical context.

    •  If needed probe to bone test can be useful in diagnosing suspected osteomyelitis.

    •  A swab from an ulcer commonly will grow something—not necessarily indicating it is infected but further testing and consideration of all clinical factors are required.

    Revised Guidelines on Diabetic Foot Infections (DFI) 2012

    •  Clinical diagnosis of DFI should incorporate systemic signs.

    •  Assessment of affected limb for risk factors is crucial.

    •  Presence of two of three classic symptoms/signs (inflammation or purulence) in the affected wound is considered a key diagnostic criterion.

    Antimicrobial Treatment

    •  Treatment for mild or moderate infections typically involves empiric therapy— such as flucloxacillin— tailored for the specific clinical setting.

    •  Severe infections, or those with known or suspected resistant organisms, frequently necessitate intravenous treatments—such as flucloxacillin—in combination with other therapies where necessary to prevent or treat complications. Further treatments may be initiated after culture (including tissue/bone) has been conducted. 

    •  Deep foot ulcers require anaerobic coverage and may involve co-amoxiclav or piperacillin-tazobactam intravenous treatment, possibly supplemented with vancomycin in cases with suspected MRSA or Pseudomonas infection.

    •  Osteomyelitis cases require empirical treatment with co-amoxiclav or piperacillin-tazobactam.

    •  Duration of treatment should be at least 28 days, but may be extended depending on factors including clinical presentation, extent of tissue involvement, and adequacy of debridement and vascular supply.

    Prevention of Infections in Diabetes

    •  Maintaining a healthy lifestyle through physical activity, smoking cessation, good hygiene practices, and a balanced diet rich in fruits, vegetables, and whole grains to maintain a healthy immune system.

    •  Foot care, including self-inspection, correct footwear usage, and podiatrist visits, are vital preventative measures. 

    •  Medical management includes optimized glucose control, management of other comorbidities, and vaccinations.

    •  Vaccination against infectious diseases such as COVID-19, influenza, and S. pneumoniae is essential.

    Classification of Cellulitis Severity

    •  Mild cellulitis is localized to the skin and subcutaneous tissue. 

    •  Moderate cellulitis encompasses symptoms of erythema around the ulcer with greater extent and further diagnostic criteria.

    •  Severe cellulitis is characterized by local infection signs and two indicative systemic criteria that are often associated with SIRS.

    Determining Infection Severity

    •  Assessment of infection severity should be based on careful evaluation of clinical indicators. 

    General Principles for Antimicrobials in Cellulitis/Osteomyelitis

    • Treatment for mild to moderate cases of infections should use Gram-positive cocci agents only unless risk factors for Pseudomonas are noted.

    •  Severe infections require broad-spectrum empiric therapy, necessitating close monitoring of results and possible urgent surgical consultation if there are significant signs such as the presence of gas in deeper tissues, necrotizing fasciitis, or abscesses.

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    Test your knowledge on Necrotizing Otitis Externa and its association with diabetes mellitus. This quiz covers various aspects including common organisms, complications, clinical features, and treatment options related to the condition. Additionally, explore the prevalence and characteristics of diabetes in relation to infections.

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