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What is Dextrose 50% in Water (D50W)?
What is Dextrose 50% in Water (D50W)?
What is the classification of Dextrose 50% in Water (D50W)?
What is the classification of Dextrose 50% in Water (D50W)?
Carbohydrate
What is the mechanism of action of Dextrose 50% in Water (D50W)?
What is the mechanism of action of Dextrose 50% in Water (D50W)?
Provides immediate source of glucose for cellular metabolism.
What are the indications for using Dextrose 50% in Water (D50W)?
What are the indications for using Dextrose 50% in Water (D50W)?
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Are there any absolute contraindications to the IV administration of Dextrose 50% in Water?
Are there any absolute contraindications to the IV administration of Dextrose 50% in Water?
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What are the potential side effects of Dextrose 50% in Water (D50W)?
What are the potential side effects of Dextrose 50% in Water (D50W)?
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What precautions should be taken when administering Dextrose 50% in Water (D50W)?
What precautions should be taken when administering Dextrose 50% in Water (D50W)?
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What drug interactions are associated with Dextrose 50% in Water (D50W)?
What drug interactions are associated with Dextrose 50% in Water (D50W)?
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What are the routes of administration for Dextrose 50% in Water (D50W)?
What are the routes of administration for Dextrose 50% in Water (D50W)?
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What is the typical onset and duration of action for Dextrose 50% in Water (D50W)?
What is the typical onset and duration of action for Dextrose 50% in Water (D50W)?
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What is the adult dosage for Dextrose 50% in Water (D50W)?
What is the adult dosage for Dextrose 50% in Water (D50W)?
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What precaution should be taken regarding concentration in neonates when administering Dextrose 50% in Water (D50W)?
What precaution should be taken regarding concentration in neonates when administering Dextrose 50% in Water (D50W)?
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Study Notes
Dextrose 50% in Water (D50W)
- Contains 25 grams of dextrose in a 50 ml solution, commonly used in medical settings.
Classification
- Categorized as a carbohydrate, which serves as a vital energy source for the body.
Mechanism of Action
- Acts as an immediate source of glucose, facilitating cellular metabolism essential for energy production.
Indications
- Primarily indicated for altered level of consciousness (ALOC) due to confirmed or suspected hypoglycemia.
Contraindications
- No absolute contraindications for IV administration in emergencies.
- Relative caution required in patients with increasing intracranial pressure to avoid worsening cerebral edema.
Side Effects
- Patients may experience discomfort such as warmth, pain, or burning sensation at the injection site.
- Risk of severe neurologic complications, like Wernicke's encephalopathy or Korsakoff's psychosis, in patients who are thiamine deficient.
Precautions
- Important to aspirate before administration and after every 10-15 ml to ensure IV patency and prevent necrosis.
- Utilize the largest vein possible and maintain a wide-open IV flow before and after administration.
- Caution is advised in cases of increased intracranial pressure due to potential exacerbation of edema or necrosis.
Interactions
- No known drug interactions reported.
Routes of Administration
- Administered intravenously (IV) or intraosseously (IO).
Onset and Duration of Actions
- Onset of action is rapid, occurring within 30-60 seconds; duration varies depending on the extent and cause of hypoglycemia.
Dosages
- Adults: 25 grams (50 ml solution) administered IV push (IVP) or intraosseously (IO), may repeat once in 5 minutes.
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Pediatric:
- Birth to 1 month: 5-10 ml/kg slow IVP of a 10% solution; may repeat once in 10 minutes.
- 1 month to 2 years: 2 ml/kg slow IVP/IO of a 25% solution; may repeat once in 5 minutes.
- Over 2 years: 1 ml/kg slow IVP/IO of a 50% solution (same as adult); may repeat once in 5 minutes.
Notes
- In neonates, concentration should not exceed 12.5% to avoid complications.
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Explore essential flashcards on Dextrose 50% in Water (D50W). This quiz provides key information including its classification, mechanism of action, and application in cellular metabolism. Perfect for students and professionals needing a quick review of this important carbohydrate solution.
