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Depression and Antidepressant Drugs

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Questions and Answers

What is the primary mechanism of action of lithium carbonate?

Regulation of thyroid function

Inhibition of kinases

Stimulation of nephrogenic diabetes insipidus

Interference with inositol trisphosphate formation (correct)

What is the primary indication for lithium treatment?

Treatment of anxiety disorders

Treatment of unipolar depression

Treatment of schizophrenia

Prophylaxis and treatment of mania (correct)

What is a potential side effect of lithium toxicity?

Hypothyroidism

Tachycardia

Cerebellar effects (correct)

Seizures

How is lithium eliminated from the body?

Via the kidneys Signup and view all the answers

What can precipitate lithium toxicity?

Diuretics Signup and view all the answers

What is a common adverse effect of chronic lithium use?

Thyroid disorders Signup and view all the answers

What is an alternative drug to lithium?

All of the above Signup and view all the answers

What is the therapeutic window for lithium?

Narrow Signup and view all the answers

How is the dose of lithium adjusted?

Based on the plasma concentration Signup and view all the answers

What is a potential complication of lithium use during chronic treatment?

Mild cognitive impairment Signup and view all the answers