Antidepressants Quiz

Insomnia and 5HT Receptor Activity

• A medication with mixed 5HT receptor activity commonly used for insomnia is Trazodone.

Serotonin Syndrome Symptoms

• Symptoms include confusion, rapid heart rate, high blood pressure, dilated pupils, muscle rigidity, and gastrointestinal issues.

NDRI for Smoking Cessation

• Bupropion is an NDRI that acts as a norepinephrine and dopamine reuptake inhibitor, also utilized for smoking cessation.

Duloxetine Neurotransmitter Action

• Duloxetine inhibits the reuptake of serotonin and norepinephrine.

Medication Half-Life and Sexual Dysfunction

• The medication with a half-life of approximately 66 hours aimed at reducing sexual dysfunction is Vardenafil.

Benzodiazepine Adverse Effects

• Hallucinations are NOT an adverse effect of benzodiazepines.

Benzodiazepine Dose Reduction Approach

• A recommended approach for reducing the dose during withdrawal is a gradual tapering schedule.

Buspirone (Buspar) and Anxiety

• An effect of buspirone treatment includes reduced anxiety without sedation.

Mechanism of Action of Buspirone

• Buspirone acts as a serotonin receptor agonist, particularly at the 5HT1A receptor.

Benzodiazepine Transition Considerations

• Considerations when switching to a long half-life benzodiazepine include patient's history of withdrawal symptoms and current dosage.

Antidepressants and Bipolar Disorder

• Antidepressants can induce manic episodes in patients with bipolar disorder.

First-Line Treatment for GAD

• Selective serotonin reuptake inhibitors (SSRIs) are the first-line pharmacological treatment for General Anxiety Disorder (GAD).

Neurotransmitter Deficiency in GAD

• A deficiency in serotonin is commonly associated with General Anxiety Disorder (GAD).

'Cheese Crisis' and Antidepressants

• Monoamine oxidase inhibitors (MAOIs) are associated with the 'cheese crisis' due to their interaction with tyramine-rich foods.

Safety in Antidepressant Classes

• SSRIs are known for their advanced safety in treating depression and effectiveness in managing anxiety disorders, obsessive-compulsive disorder, and eating disorders.