15 Questions
Which medication listed is a mixed 5HT receptor activity and is used more commonly for insomnia?
Mirtazapine
What are the symptoms of Serotonin Syndrome?
Tremor, sweating, dilated pupils
Which antidepressant is a NE and DA reuptake inhibitor (NDRI) and is also used for smoking cessation?
Bupropion
Which neurotransmitters does Duloxetine block the reuptake of?
Both 5HT and NE
Which medication has a half-life of approximately 66 hours and aims to reduce sexual dysfunction?
Vortioxetine
Which of the following is NOT an adverse effect of benzodiazepines?
Psychosis
What is the recommended approach for reducing the dose of benzodiazepines during withdrawal?
Reduce by 5 – 10% each 1 – 2 weeks
Which of the following represents an effect of buspirone (Buspar) treatment for anxiety?
Slow onset and modest efficacy
What is the mechanism of action of buspirone (Buspar)?
Unknown mechanism of action
What should be considered when switching benzodiazepines to a long half-life drug to reduce withdrawal symptoms?
Life-threatening withdrawal seizures may be reduced
What can antidepressants induce in bipolar disorder patients?
Manic episodes
What is the first-line pharmacological treatment for general anxiety disorder (GAD)?
SSRI and SNRI
Which neurotransmitter deficiency is associated with general anxiety disorder (GAD)?
Serotonin (5HT)
Which antidepressant class is associated with the 'cheese crisis' due to interactions with tyramine-rich foods?
Monoamine Oxidase Inhibitors (MAOIs)
Which antidepressant class is known for its advanced safety in the treatment of depression and its ability to treat anxiety disorders, obsessive-compulsive disorder, and eating disorders?
Selective Serotonin Reuptake Inhibitors (SSRIs)
This lecture covers the hypothesized pathophysiology of depression, the rationale for the progression of drug development, medication side effects, and the process of selecting medication based on patient comorbidities and past medication history. The lecture also provides an overview of patient interviews related to medication selection, including past medication history and family history.
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