Dental Odontoblasts and Dentin Regeneration
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Questions and Answers

What type of dentin is produced if the odontoblasts survive the injury?

  • Tubular dentin
  • Osteodentin
  • Normal dentin
  • Reparative dentin (correct)

What happens to the odontoblasts if they are killed due to injury?

  • They produce tubular dentin
  • They undergo regeneration
  • They are replaced by undifferentiated cells from deeper regions of the pulp (correct)
  • They survive and produce normal dentin

What is the term used for the newly formed dentin as a result of the healing process initiated by the pulp?

  • Reparative dentin (correct)
  • Normal dentin
  • Tubular dentin
  • Osteodentin

What is a characteristic feature of reparative dentin?

<p>Fewer and more twisted tubules than normal dentin (A)</p> Signup and view all the answers

In what instances is osteodentin seen especially?

<p>In response to rapidly progressing caries (A)</p> Signup and view all the answers

Where does the origin of the new odontoblast occur from?

<p>Cells in the cell-rich zone or undifferentiated perivascular cells in deeper pulp regions (C)</p> Signup and view all the answers

What is the role of transforming growth factor-beta (TGF-b) in dentin formation?

<p>It is involved in the production of tubular dentin (C)</p> Signup and view all the answers

What stimulates pulpal response leading to reparative dentin formation?

<p>Chemical substances from restorative materials (D)</p> Signup and view all the answers

What distinguishes irregular secondary dentin from regular secondary dentin?

<p>It is formed as a result of external stimuli (D)</p> Signup and view all the answers

What is a characteristic feature of tertiary dentin formation?

<p>Variation in mineral content and irregular circumference (A)</p> Signup and view all the answers

What is believed to be involved in the production of osteodentin?

<p>Bone morphogenetic protein (BMP) (C)</p> Signup and view all the answers

What influences the formation of interglobular dentin in tertiary dentin?

<p>Biological rhythms (D)</p> Signup and view all the answers

What is absent in tertiary dentin, distinguishing it from other forms of dentin?

<p>Dentin phosphophoryn (A)</p> Signup and view all the answers

What may be less ordered during tertiary dentin formation compared to primary dentinogenesis?

<p>The molecular mediators (A)</p> Signup and view all the answers

What differentiates irregular secondary dentin from regular secondary dentin?

<p>Formation due to external stimuli (A)</p> Signup and view all the answers

What type of dentin formation is influenced by biological rhythms?

<p>Tertiary dentin (C)</p> Signup and view all the answers

Which growth factor is believed to be involved in the production of tubular dentin?

<p>Transforming growth factor-beta (TGF-b) (A)</p> Signup and view all the answers

What stimulates pulpal response leading to reparative dentin formation?

<p>Living or dead bacteria, their toxic products, and chemical substances from restorative materials (B)</p> Signup and view all the answers

What is the main difference between irregular secondary dentin and regular secondary dentin?

<p>Formation as a result of external stimuli (D)</p> Signup and view all the answers

What do ultrastructural studies reveal about tertiary dentin formation?

<p>Variation in the size and shape of dentinal tubules (A)</p> Signup and view all the answers

What is believed to influence the formation of interglobular dentin in tertiary dentin?

<p>Biological rhythms (A)</p> Signup and view all the answers

What molecular mediator appears to be common to both development and repair processes?

<p>Matrix-mediated cellular processes (D)</p> Signup and view all the answers

What is the main difference between irregular secondary dentin and osteodentin?

<p>Involvement of bone morphogenetic protein (BMP) (A)</p> Signup and view all the answers

What is the suggested role of bone morphogenetic protein (BMP) in dentin production?

<p>Production of osteodentin (B)</p> Signup and view all the answers

What are the primary sources of stimuli that lead to irregular secondary dentin formation?

<p>Bacterial migration down the tubules and chemical substances from restorative materials. (B)</p> Signup and view all the answers

What sets tertiary dentin apart from other forms of dentin?

<p>The presence of interglobular dentin. (B)</p> Signup and view all the answers

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