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Dental Odontoblasts and Dentin Regeneration
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Dental Odontoblasts and Dentin Regeneration

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Questions and Answers

What type of dentin is produced if the odontoblasts survive the injury?

  • Tubular dentin
  • Osteodentin
  • Normal dentin
  • Reparative dentin (correct)
  • What happens to the odontoblasts if they are killed due to injury?

  • They produce tubular dentin
  • They undergo regeneration
  • They are replaced by undifferentiated cells from deeper regions of the pulp (correct)
  • They survive and produce normal dentin
  • What is the term used for the newly formed dentin as a result of the healing process initiated by the pulp?

  • Reparative dentin (correct)
  • Normal dentin
  • Tubular dentin
  • Osteodentin
  • What is a characteristic feature of reparative dentin?

    <p>Fewer and more twisted tubules than normal dentin</p> Signup and view all the answers

    In what instances is osteodentin seen especially?

    <p>In response to rapidly progressing caries</p> Signup and view all the answers

    Where does the origin of the new odontoblast occur from?

    <p>Cells in the cell-rich zone or undifferentiated perivascular cells in deeper pulp regions</p> Signup and view all the answers

    What is the role of transforming growth factor-beta (TGF-b) in dentin formation?

    <p>It is involved in the production of tubular dentin</p> Signup and view all the answers

    What stimulates pulpal response leading to reparative dentin formation?

    <p>Chemical substances from restorative materials</p> Signup and view all the answers

    What distinguishes irregular secondary dentin from regular secondary dentin?

    <p>It is formed as a result of external stimuli</p> Signup and view all the answers

    What is a characteristic feature of tertiary dentin formation?

    <p>Variation in mineral content and irregular circumference</p> Signup and view all the answers

    What is believed to be involved in the production of osteodentin?

    <p>Bone morphogenetic protein (BMP)</p> Signup and view all the answers

    What influences the formation of interglobular dentin in tertiary dentin?

    <p>Biological rhythms</p> Signup and view all the answers

    What is absent in tertiary dentin, distinguishing it from other forms of dentin?

    <p>Dentin phosphophoryn</p> Signup and view all the answers

    What may be less ordered during tertiary dentin formation compared to primary dentinogenesis?

    <p>The molecular mediators</p> Signup and view all the answers

    What differentiates irregular secondary dentin from regular secondary dentin?

    <p>Formation due to external stimuli</p> Signup and view all the answers

    What type of dentin formation is influenced by biological rhythms?

    <p>Tertiary dentin</p> Signup and view all the answers

    Which growth factor is believed to be involved in the production of tubular dentin?

    <p>Transforming growth factor-beta (TGF-b)</p> Signup and view all the answers

    What stimulates pulpal response leading to reparative dentin formation?

    <p>Living or dead bacteria, their toxic products, and chemical substances from restorative materials</p> Signup and view all the answers

    What is the main difference between irregular secondary dentin and regular secondary dentin?

    <p>Formation as a result of external stimuli</p> Signup and view all the answers

    What do ultrastructural studies reveal about tertiary dentin formation?

    <p>Variation in the size and shape of dentinal tubules</p> Signup and view all the answers

    What is believed to influence the formation of interglobular dentin in tertiary dentin?

    <p>Biological rhythms</p> Signup and view all the answers

    What molecular mediator appears to be common to both development and repair processes?

    <p>Matrix-mediated cellular processes</p> Signup and view all the answers

    What is the main difference between irregular secondary dentin and osteodentin?

    <p>Involvement of bone morphogenetic protein (BMP)</p> Signup and view all the answers

    What is the suggested role of bone morphogenetic protein (BMP) in dentin production?

    <p>Production of osteodentin</p> Signup and view all the answers

    What are the primary sources of stimuli that lead to irregular secondary dentin formation?

    <p>Bacterial migration down the tubules and chemical substances from restorative materials.</p> Signup and view all the answers

    What sets tertiary dentin apart from other forms of dentin?

    <p>The presence of interglobular dentin.</p> Signup and view all the answers

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