18 Questions
What is the life span of a platelet?
10 days
Which cell gives rise to platelets through fragmentation of cytoplasm?
Megakaryoblast
What is the unique feature of a megakaryocyte's nucleus during maturation?
Polyploidy
What organelle is abundant in the cytoplasm of a megakaryocyte?
Mitochondria
Which event leads to the formation of demarcation membranes within a megakaryocyte?
Plasma membrane invaginations
What is the approximate range of platelet count per mm3 of blood in adults?
~200,000 - 350,000
What is the main function of the dense tubular system in platelets?
Ca sequestration during resting states and release upon activation
Which type of granule in platelets contains growth factors and adhesive proteins?
Alpha granules (a-granules)
What is the main function of Delta granules (δ-granules) in platelets?
Contain hemostatically active molecules for vasoconstriction
Which organelle in platelets is responsible for clot resorption?
Lambda granules (λ-granules)
What is the role of platelets in haemostatic process after injury to the vessel wall?
Deaccelerating by tethering to the site of injury
Which structure in platelets is involved in the generation of ATP for platelet activation?
Granulomere
Which of the following is NOT a component of the platelet cytosol?
Rough endoplasmic reticulum
What is the primary function of the microtubules in the platelet cytoskeleton?
Maintain the discoid morphology of platelets
Which of the following statements about the open canalicular system (OCS) in platelets is correct?
It facilitates the entry of external elements into platelets and the release of granule contents
What is the primary function of the glycoprotein molecules (GPs) present in the platelet plasmalemma?
Interact with vessel wall components and molecules involved in platelet adhesion
Which of the following statements about the demarcation membranes in thrombopoiesis is correct?
They outline areas of the cytoplasm that will be fragmented, forming the platelets
What is the primary function of the actin and myosin filaments in the platelet cytoskeleton?
Participate in platelet movements and retraction during hemostasis
Test your knowledge on the dense tubular system and granulomere, two important structures in cells involved in various functions such as Ca sequestration and ATP generation. Learn about their composition and roles within the cell.
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