Data Structures ListenT and Immune System
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Questions and Answers

Which of the following best describes the primary function of the immune system?

  • To provide resistance against infections. (correct)
  • To regulate body temperature through sweat glands.
  • To transport oxygen and carbon dioxide throughout the body.
  • To facilitate the digestion and absorption of nutrients.

Which of the following is the most accurate definition of 'Immune response'?

  • The process of inflammation triggered by physical injury.
  • The immediate secretion of digestive enzymes after food intake.
  • The body's reaction to changes in atmospheric pressure.
  • The coordinated reaction of cells and molecules to infectious microbes. (correct)

If a substance triggers an immune response, it is reasonable to assume that the body recognizes the substance as:

  • Harmful and requiring a defensive action. (correct)
  • Beneficial and nutritious.
  • Having no effect on the body’s functions.
  • A normal component of body tissues.

What encompasses the study of the immune system, including its responses to pathogens and its role in disease?

<p>Immunology (C)</p> Signup and view all the answers

Which of the following is the broadest term, encompassing all others?

<p>Immunity (D)</p> Signup and view all the answers

Which statement accurately differentiates between immunity and the immune system?

<p>Immunity is the resistance to disease; the immune system is the collection of cells, tissues, and molecules that mediate this. (B)</p> Signup and view all the answers

If a researcher is investigating the specific cellular and molecular mechanisms the body uses to combat a novel viral infection, which field of study are they primarily working in?

<p>Immunology (D)</p> Signup and view all the answers

How are 'Immune response' and 'Immune system' related?

<p>The immune system produces the reaction called the immune response. (D)</p> Signup and view all the answers

Which process describes phagocytosis MOST accurately?

<p>The engulfment and degradation of microbes by phagocytic cells, coupled with the secretion of cytokines and chemokines. (B)</p> Signup and view all the answers

A researcher observes a large number of cells releasing enzymes that damage parasite cell walls, but also notes concurrent damage to surrounding host tissues. Which cell type is MOST likely involved?

<p>Eosinophils (A)</p> Signup and view all the answers

Which of the following is the PRIMARY function of B lymphocytes in humoral immunity?

<p>Producing antibodies that neutralize antigens. (B)</p> Signup and view all the answers

A patient's immune response is failing to control an intracellular bacterial infection. Which type of T lymphocyte would be MOST beneficial in restoring immune function?

<p>Helper T lymphocytes (CD4+) (A)</p> Signup and view all the answers

Following a tissue injury, which cell type is MOST responsible for clearing dead tissues and initiating the process of tissue repair?

<p>Macrophages (A)</p> Signup and view all the answers

Why is the interaction between T lymphocytes and antigen-presenting cells (APCs) MOST critical for adaptive immunity?

<p>It facilitates the activation of T cells, enabling them to orchestrate targeted immune responses. (C)</p> Signup and view all the answers

Which of the following mediators are secreted by phagocytic cells to recruit and activate other immune cells during an infection?

<p>Cytokines and chemokines (C)</p> Signup and view all the answers

In a patient with a viral infection, which of the following immune responses would MOST effectively eliminate virus-infected cells?

<p>Cytotoxic T lymphocytes (CTLs)-mediated killing of infected cells. (B)</p> Signup and view all the answers

Which of the following is the primary function of natural killer (NK) cells in innate immunity?

<p>Killing infected or stressed cells and secreting IFN-γ. (A)</p> Signup and view all the answers

Cytokines mediate inflammatory reactions and communication between cells. Which cells are the principal sources of these cytokines in innate immunity?

<p>Dendritic cells and macrophages. (B)</p> Signup and view all the answers

Which of the following is a function of chemokines?

<p>Mediating chemotaxis to stimulate leukocyte movement (C)</p> Signup and view all the answers

Which of the following is a function of the complement system?

<p>Promoting the recruitment of phagocytes to the site of infection. (D)</p> Signup and view all the answers

Which of the following best describes the function of secreted antibodies?

<p>Neutralizing toxins and preventing the spread of pathogens. (A)</p> Signup and view all the answers

How does the complement protein C3b function in eliminating pathogens?

<p>By opsonizing microbes to enhance phagocytosis (D)</p> Signup and view all the answers

Which type of cells exclusively produce immunoglobulins (antibodies)?

<p>B Lymphocytes (D)</p> Signup and view all the answers

What is the primary role of interferons?

<p>Inhibiting viral replication (D)</p> Signup and view all the answers

The adaptive immune system relies heavily on cytokines produced by helper T lymphocytes. What is the primary function of these cytokines?

<p>Activating B lymphocytes to produce antibodies (C)</p> Signup and view all the answers

How do membrane-bound antibodies function on the surface of B lymphocytes?

<p>As receptors for antigens (B)</p> Signup and view all the answers

Which of the following is a central (primary) immune organ?

<p>Bone marrow (C)</p> Signup and view all the answers

Which of the following is NOT a recognized effect of the complement system?

<p>Inhibition of chemotaxis (D)</p> Signup and view all the answers

Monokines are a specific class of cytokines. Which cells produce monokines?

<p>Monocytes (B)</p> Signup and view all the answers

What is the main function of peripheral (secondary) immune organs?

<p>Initiating immune responses by allowing immune cells to respond to antigens. (B)</p> Signup and view all the answers

How do lymph nodes contribute to immune function?

<p>They serve as filters for blood, removing infectious agents and activating immune cells. (D)</p> Signup and view all the answers

What is the key distinction between the role of cytokines in innate versus adaptive immunity?

<p>In adaptive immunity, cytokines are mainly produced by helper T lymphocytes, while in innate immunity, they are derived from dendritic cells and macrophages. (D)</p> Signup and view all the answers

Interleukins are a subset of cytokines. Which cells primarily produce interleukins?

<p>T-helper cells (C)</p> Signup and view all the answers

Which of the following is a function of the spleen?

<p>Filtering blood and removing old red blood cells (B)</p> Signup and view all the answers

Where are mast cells primarily located, and what is contained within their cytoplasmic granules?

<p>Skin and mucosal epithelia; histamine and other mediators (B)</p> Signup and view all the answers

Which of the following statements accurately describes the relationship between lymphokines and lymphocytes?

<p>Lymphocytes produce lymphokines. (B)</p> Signup and view all the answers

What is the role of antigen-presenting cells (APCs) in T cell activation?

<p>To present processed antigens to T cells, enabling T cell activation. (A)</p> Signup and view all the answers

If a patient has a compromised thymus, which immune function would be most directly affected?

<p>The maturation and development of T cells. (B)</p> Signup and view all the answers

Why is the presentation of antigen by antigen-presenting cells crucial for T cell activation?

<p>Antigen presentation ensures that T cells only respond to antigens associated with infected or abnormal cells. (D)</p> Signup and view all the answers

A patient's lab results show a significant decrease in granulocytes. Which type of infection are they now more susceptible to?

<p>Bacterial infections, as granulocytes like neutrophils engulf and kill bacteria. (A)</p> Signup and view all the answers

What would be the likely consequence of removing the spleen from an otherwise healthy individual?

<p>Compromised ability to filter blood and remove pathogens. (A)</p> Signup and view all the answers

How do mast cells contribute to allergic reactions?

<p>By releasing histamine and other mediators upon allergen exposure. (B)</p> Signup and view all the answers

Why are bone marrow transplants often used in the treatment of certain immune deficiencies and cancers?

<p>Bone marrow contains stem cells that can generate all blood and immune cells. (A)</p> Signup and view all the answers

A new drug is designed to inhibit the function of antigen-presenting cells. What potential side effect should be closely monitored in patients taking this drug?

<p>Compromised ability to initiate T cell-mediated immune responses (B)</p> Signup and view all the answers

Considering the roles of central and peripheral immune organs, what explains why both are necessary for a fully functional immune system?

<p>Central organs generate immune cells, while peripheral organs facilitate their activation and response to antigens. (C)</p> Signup and view all the answers

A researcher is investigating how immune cells differentiate into specialized subtypes to perform specific functions. Which area of study is this?

<p>Cellular immunology (D)</p> Signup and view all the answers

A scientist discovers a new protein that enhances the ability of macrophages to engulf and destroy bacteria. Which aspect of immunity is most directly affected by this protein?

<p>Innate immunity (C)</p> Signup and view all the answers

A vaccine is designed to stimulate the production of antibodies that neutralize a specific viral protein. Which branch of the immune system is primarily being activated by this vaccine?

<p>Humoral immunity (C)</p> Signup and view all the answers

In a patient with a genetic defect that impairs the development of T helper cells, which immunological process would be most directly compromised?

<p>Activation of B cells and antibody production (C)</p> Signup and view all the answers

A researcher is studying the mechanisms by which the immune system distinguishes between 'self' and 'non-self.' Deficiencies in this process can lead to which of the following?

<p>Autoimmune diseases (B)</p> Signup and view all the answers

Which of the following statements BEST captures the essence of 'immunity' in an organism?

<p>The inherent ability of the organism to resist diseases, particularly infectious ones. (C)</p> Signup and view all the answers

The immune system comprises various elements that work in concert. Which option provides the MOST comprehensive description of the immune system?

<p>The integrated network of cells, tissues, and molecules that mediate overall resistance to infections. (D)</p> Signup and view all the answers

Consider a scenario where the body encounters a bacterial pathogen. Which term BEST describes the series of events and reactions that occur within the body to combat this pathogen?

<p>Immune Response (A)</p> Signup and view all the answers

A researcher is studying the mechanisms by which the body distinguishes between its own cells and foreign invaders. Which field of study does this BEST represent?

<p>Immunology (C)</p> Signup and view all the answers

Which of the following concepts includes the other concepts?

<p>Immunology. (C)</p> Signup and view all the answers

What is the key element that differentiates the term 'immunity' from the term 'immune response'?

<p>Immunity is the resistance to disease mediated by the immune system, while the immune response is the reaction to infectious microbes. (D)</p> Signup and view all the answers

If a scientist is conducting research focused on the cellular interactions and molecular events during an allergic reaction, which field of study are they primarily engaged in?

<p>Immunology (C)</p> Signup and view all the answers

How do 'Immune response' and 'Immune system' relate to one another?

<p>The immune system carries out immune responses. (C)</p> Signup and view all the answers

Eosinophils are MOST likely to cause tissue damage due to which of the following reasons?

<p>Release of cytotoxic enzymes intended for parasite cell walls. (B)</p> Signup and view all the answers

Which of the following processes is MOST directly associated with the adaptive, rather than the innate, immune response?

<p>Antibody-mediated neutralization of antigens. (D)</p> Signup and view all the answers

A patient with a genetic defect is unable to produce functional B lymphocytes. Which of the following immune responses would be MOST affected in this patient?

<p>Production of antibodies to neutralize pathogens. (C)</p> Signup and view all the answers

A researcher is investigating a new drug that enhances the ability of macrophages to clear dead cells and initiate tissue repair. This drug is MOST likely affecting which macrophage function?

<p>Phagocytosis and cytokine production. (C)</p> Signup and view all the answers

Which of the following mechanisms is MOST directly involved in the elimination of virus-infected host cells?

<p>Cell lysis by CD8+ cytotoxic T lymphocytes (CTLs). (D)</p> Signup and view all the answers

A scientist discovers that a particular infectious agent can effectively block phagosome-lysosome fusion in macrophages. Which outcome would MOST likely result from this?

<p>Enhanced intracellular replication of the infectious agent. (C)</p> Signup and view all the answers

If a patient has a deficiency in CD4+ T lymphocytes, which of the following immune functions would be MOST compromised?

<p>Activation of B lymphocytes and enhancement of phagocytosis. (D)</p> Signup and view all the answers

Which of the following is the MOST critical role of cytokines and chemokines secreted during phagocytosis?

<p>Attracting and activating other immune cells to the site of infection. (A)</p> Signup and view all the answers

What is the primary role of central immune organs, such as the bone marrow and thymus?

<p>Producing and maturing lymphocytes into functional immune cells. (C)</p> Signup and view all the answers

Which function is primarily associated with peripheral immune organs like the spleen and lymph nodes?

<p>Filtering blood, removing old red blood cells and activating immune responses to blood-borne pathogens. (B)</p> Signup and view all the answers

If a patient's spleen is removed due to trauma, what immunological consequence is most likely?

<p>Reduced ability to activate immune cells against blood-borne pathogens. (D)</p> Signup and view all the answers

Why is antigen presentation by specialized cells crucial for T cell activation?

<p>T cells can only recognize antigens when they are presented on MHC molecules. (A)</p> Signup and view all the answers

Mast cells are strategically located in tissues like the skin and mucosal epithelia. What is the primary immunological role of these cells at these locations?

<p>Releasing histamine and other mediators in response to tissue damage or allergens. (D)</p> Signup and view all the answers

A researcher is investigating how immune cells communicate with each other during an infection. Which type of molecule is MOST likely involved in this cell-to-cell communication?

<p>Cytokines (D)</p> Signup and view all the answers

Following vaccination, naive T cells become activated and differentiate into effector T cells. Where does this activation and differentiation primarily occur?

<p>Lymph nodes (A)</p> Signup and view all the answers

In an individual with a genetic defect leading to a non-functional thymus, which immune cell population would be most affected?

<p>T lymphocytes. (D)</p> Signup and view all the answers

If a researcher aims to study the earliest stages of immune cell development, which organ would be the most relevant to examine?

<p>Bone marrow (A)</p> Signup and view all the answers

Why is the organized structure of lymph nodes, with distinct T cell and B cell zones, important for adaptive immune responses?

<p>It promotes direct interaction between T cells, B cells, and antigen-presenting cells. (D)</p> Signup and view all the answers

Which of the following is a key difference between the function of the spleen and lymph nodes in the immune system?

<p>The spleen filters blood and removes old red blood cells, while lymph nodes filter lymph and activate immune cells. (D)</p> Signup and view all the answers

A patient with a rare genetic disorder has a deficiency in mast cells. Which of the following immune responses would be most affected in this patient?

<p>Immediate hypersensitivity reactions (e.g., allergies) (C)</p> Signup and view all the answers

In an experiment, researchers selectively deplete a specific cell type and then observe a significant decrease in the ability of the immune system to activate T cells. Which cell type was most likely depleted?

<p>Antigen-presenting cells (APCs) (B)</p> Signup and view all the answers

If a researcher is studying the migration patterns of immune cells during inflammation, which type of molecule would be most relevant to investigate?

<p>Chemokines (B)</p> Signup and view all the answers

A researcher is studying how the immune system recognizes a newly discovered bacterium. They notice that certain cells are engulfing and breaking down the bacteria. Which process are they most likely observing?

<p>Phagocytosis (C)</p> Signup and view all the answers

Which of the following best describes the role of cytokines in both innate and adaptive immunity?

<p>Mediating communication between leukocytes and other cells. (D)</p> Signup and view all the answers

Considering their roles in the immune response, what is the key difference between interleukins and monokines?

<p>Interleukins are produced by T-helper cells, while monokines are produced exclusively by monocytes. (D)</p> Signup and view all the answers

In an infection, what is the MOST direct mechanism by which the complement system enhances the immune response?

<p>Enhancing phagocytosis through opsonization. (D)</p> Signup and view all the answers

How do membrane-bound antibodies on B lymphocytes contribute to the adaptive immune response?

<p>Functioning as antigen receptors to initiate B cell activation. (B)</p> Signup and view all the answers

Which of the following is the MOST accurate description of how the complement protein C3b enhances phagocytosis?

<p>By acting as an opsonin, facilitating the attachment of phagocytes to pathogens. (C)</p> Signup and view all the answers

If a patient is deficient in NK cells, which type of immune response would be MOST compromised?

<p>Killing of virus-infected cells and secretion of macrophage-activating cytokines. (B)</p> Signup and view all the answers

What is the primary role of chemokines in an immune response?

<p>Mediating chemotaxis to direct the movement of leukocytes. (C)</p> Signup and view all the answers

What is the primary function of secreted antibodies in adaptive immunity?

<p>Neutralizing toxins and preventing pathogen entry and spread. (C)</p> Signup and view all the answers

How do interferons primarily contribute to antiviral immunity?

<p>By interfering with viral replication within infected cells. (C)</p> Signup and view all the answers

What is the MOST significant difference between the sources of cytokines in innate versus adaptive immunity?

<p>In innate immunity, the cytokines are primarily produced by dendritic cells and macrophages, while in adaptive immunity, helper T lymphocytes are a major source. (D)</p> Signup and view all the answers

Which process is MOST directly facilitated by the secretion of cytokines?

<p>Communication between leukocytes and other cells. (D)</p> Signup and view all the answers

What is the PRIMARY mechanism by which natural killer (NK) cells recognize infected or stressed cells?

<p>Recognition of infected and stressed cells. (A)</p> Signup and view all the answers

If a researcher is studying how the immune system recruits phagocytes to the site of an infection, which class of molecules would be of MOST interest?

<p>Chemokines. (A)</p> Signup and view all the answers

Which outcome would MOST likely follow the activation of the complement system?

<p>Enhanced phagocytosis due to opsonization of microbes. (B)</p> Signup and view all the answers

Which of the following cell types is specialized to synthesize and secrete antibodies?

<p>B lymphocytes. (C)</p> Signup and view all the answers

A previously healthy individual is exposed to a new, highly contagious virus. Which of the following innate immune responses would provide the earliest defense against this virus?

<p>Interferon production by infected cells to induce antiviral state in neighboring cells. (B)</p> Signup and view all the answers

A researcher is investigating a novel bacterium and observes that it can survive and replicate inside macrophages. Which alteration of the bacterium would MOST likely prevent its intracellular survival?

<p>Inability to prevent fusion of the phagosome with lysosomes. (B)</p> Signup and view all the answers

A patient with a genetic mutation has impaired production of functional complement proteins. This defect would MOST directly compromise which of the following immune functions?

<p>Opsonization and direct lysis of bacteria. (D)</p> Signup and view all the answers

In a patient with a parasitic worm infection, which of the following cellular responses would be MOST effective in eliminating the parasite?

<p>Eosinophil degranulation and release of toxic mediators. (D)</p> Signup and view all the answers

A researcher is studying how a new vaccine activates the adaptive immune response. They observe increased expression of co-stimulatory molecules on dendritic cells after vaccination. What is the MOST likely consequence of this increased co-stimulation?

<p>Enhanced activation of naive T lymphocytes. (C)</p> Signup and view all the answers

Which cell type is exclusively responsible for the production of antibodies that neutralize and eliminate antigens?

<p>B lymphocytes (A)</p> Signup and view all the answers

What is the primary role of CD4+ T lymphocytes in adaptive immunity?

<p>Activating phagocytes, recruiting leukocytes, and activating B lymphocytes (A)</p> Signup and view all the answers

Which of the following accurately describes phagocytosis?

<p>The engulfment and degradation of microbes by phagocytic cells. (A)</p> Signup and view all the answers

Following phagocytosis, which event contributes to the recruitment and activation of other immune cells?

<p>Secretion of cytokines and chemokines. (B)</p> Signup and view all the answers

What function do cytoplasmic granules found in eosinophils perform?

<p>Damaging parasite cell walls and, potentially, host tissues. (A)</p> Signup and view all the answers

Which of the following functions is primarily associated with macrophages?

<p>Producing cytokines to induce inflammation, ingesting microbes, clearing dead tissues, and initiating tissue repair (D)</p> Signup and view all the answers

What is the main function of CD8+ cytotoxic T lymphocytes (CTLs)?

<p>Killing infected cells harboring microbes in the cytoplasm (D)</p> Signup and view all the answers

Which of the following cell types shares structural and functional similarities with mast cells?

<p>Basophils (D)</p> Signup and view all the answers

Which of the following scenarios BEST exemplifies 'immunity' in action?

<p>A person recovers from the flu and is now resistant to the same strain. (B)</p> Signup and view all the answers

If a researcher aims to study the collaborative action of various cells and molecules in response to a viral infection, which of the following would be MOST relevant to investigate?

<p>The coordinated immune response. (B)</p> Signup and view all the answers

Consider a situation where an individual's body demonstrates a heightened sensitivity and reactivity upon subsequent exposure to a substance. To what is the body MOST likely reacting?

<p>A foreign substance. (C)</p> Signup and view all the answers

Which activity falls MOST directly under the purview of immunology as a field of study?

<p>Studying the interaction between immune cells and cancer cells. (C)</p> Signup and view all the answers

A scientist is conducting research focused solely on understanding the mechanisms of resistance to infectious diseases. Which of the following concepts would be MOST relevant to this research?

<p>Immunity. (B)</p> Signup and view all the answers

A drug is developed that enhances the body's natural defenses by stimulating specific cells, tissues, and molecules. Which of the following is MOST directly affected by this new drug?

<p>The body's immune system. (D)</p> Signup and view all the answers

How does immunity fundamentally differ from the immune response?

<p>Immunity is the <em>ability</em> to resist disease, while the immune response is the coordinated <em>action</em>. (B)</p> Signup and view all the answers

A research team is investigating the detailed cellular interactions and molecular signaling pathways involved in the rejection of transplanted organs. Which field of study does this BEST describe?

<p>Immunology. (B)</p> Signup and view all the answers

What is the primary physiological role of the immune system?

<p>To prevent or eradicate infections. (C)</p> Signup and view all the answers

Which of the following components collaborate to form a functional immune system?

<p>Immune organs, immune cells, and immune molecules. (A)</p> Signup and view all the answers

What is the defining characteristic of central (primary) immune organs?

<p>They are the sites where lymphocytes are generated and mature into functional cells. (C)</p> Signup and view all the answers

Which of the following is an example of a peripheral (secondary) immune organ?

<p>Spleen (A)</p> Signup and view all the answers

What is the primary function of peripheral immune organs?

<p>Sites where immune cells respond to antigen and function. (D)</p> Signup and view all the answers

Which of the following actions best describes the function of lymph nodes?

<p>Filtering lymph to remove infectious agents and activate immune cells. (C)</p> Signup and view all the answers

What is the main function of the spleen in the immune system?

<p>Filtering blood to remove infectious agents and removing old red blood cells. (D)</p> Signup and view all the answers

In addition to filtering blood, how else does the spleen aid the immune system?

<p>It serves as a site where immune cells can be activated. (B)</p> Signup and view all the answers

What is the role of a presenting cell during an immune response?

<p>To engulf pathogens and present antigens to T cells. (C)</p> Signup and view all the answers

Why is antigen presentation by antigen-presenting cells (APCs) essential for T cell activation?

<p>T cells can't recognize antigen alone; they need the antigen presented on a major histocompatibility complex (MHC) molecule. (D)</p> Signup and view all the answers

Where are mast cells primarily located, and what is their role in immune responses?

<p>In the skin and mucosal epithelia, releasing mediators like histamine. (A)</p> Signup and view all the answers

Mast cells contain cytoplasmic granules filled with histamine and other mediators. What is the effect of these mediators?

<p>Vasodilation and increased vascular permeability. (B)</p> Signup and view all the answers

What is the primary role of the bone marrow in adaptive immunity?

<p>Producing stem cells that generate all blood and immune cells. (C)</p> Signup and view all the answers

Which cell type has delta (δ) chains?

<p>Gamma delta(γδ) T Cell (C)</p> Signup and view all the answers

Which of the following best describes the role of cytokines in the immune system?

<p>Facilitating communication between leukocytes and other cells, mediating inflammatory reactions. (A)</p> Signup and view all the answers

If a patient's immune cells are failing to effectively recruit phagocytes to sites of infection, which type of cytokine is MOST likely deficient?

<p>Chemokines (C)</p> Signup and view all the answers

In adaptive immunity, a key source of cytokines is helper T lymphocytes. What is the MAIN function of these cytokines?

<p>Regulating and coordinating the adaptive immune response. (A)</p> Signup and view all the answers

Which cells are the PRINCIPAL sources of cytokines in innate immunity?

<p>Dendritic cells and macrophages. (D)</p> Signup and view all the answers

What is the PRIMARY function of membrane-bound antibodies found on the surface of B lymphocytes?

<p>Acting as antigen receptors. (B)</p> Signup and view all the answers

How does the complement system contribute to the innate immune response?

<p>By opsonizing microbes, recruiting phagocytes, and directly killing microbes. (A)</p> Signup and view all the answers

What is the MOST direct outcome of C3b deposition on a bacterial cell surface?

<p>Opsonization, facilitating phagocytosis. (B)</p> Signup and view all the answers

Which type of immune cell is exclusively responsible for the production of antibodies?

<p>B lymphocytes (B)</p> Signup and view all the answers

What is the primary mechanism by which interferons protect against viral infections?

<p>Inducing an antiviral state in infected and nearby cells. (C)</p> Signup and view all the answers

How do secreted antibodies primarily function to eliminate microbes?

<p>By neutralizing toxins and preventing pathogen entry and spread. (D)</p> Signup and view all the answers

If a patient has a genetic defect that impairs the production of complement protein C3, which of the following immune processes would be MOST affected?

<p>Direct, complement-mediated lysis of pathogens (B)</p> Signup and view all the answers

Which scenario BEST illustrates the function of natural killer (NK) cells in innate immunity?

<p>A cell recognizing and killing a stressed cell that has lost MHC class I expression. (C)</p> Signup and view all the answers

A researcher is investigating a novel therapy to enhance chemotaxis during an infection. Which type of molecule should this therapy PRIMARILY target to improve immune cell migration to the site of infection?

<p>Chemokines (D)</p> Signup and view all the answers

A patient is diagnosed with a deficiency in interferon production. Which of the following consequences is MOST likely in this patient?

<p>Impaired ability to fight viral infections (D)</p> Signup and view all the answers

How do lymphokines differ from monokines in terms of their production?

<p>Lymphokines are produced exclusively by lymphocytes, whereas monokines are produced exclusively by monocytes. (D)</p> Signup and view all the answers

Flashcards

Immunity

Resistance to disease, especially infectious diseases.

Immune System

A collection of cells, tissues, and molecules that resist infections.

Immune Response

Coordinated reaction of immune cells and molecules to pathogens.

Immunology

The study of the immune system and its responses to pathogens.

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Infectious Disease

Diseases caused by microbes that can spread from one person to another.

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Pathogen

Microbes that can cause disease, including bacteria and viruses.

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Cells of Immune System

Various cell types like lymphocytes that play roles in immunity.

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Microbial Pathogens

Microbes that invade and disrupt normal body functions.

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Date

A specific day of the month or year

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Listening

The active process of receiving and interpreting sounds.

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Importance of Listening

Crucial for effective communication and understanding.

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Active Listening

Fully concentrating and engaging with the speaker.

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January

The first month of the year, 31 days long.

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Basophils

White blood cells that resemble mast cells, involved in immune response.

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Eosinophils

White blood cells with granules that target parasites and can harm host tissues.

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Phagocytosis

The process where phagocytes engulf and digest microbes.

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Phagocytes

Cells like Neutrophils and Monocytes that ingest microbes at infection sites.

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Macrophages

Large phagocytic cells that manage inflammation and tissue repair.

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B Lymphocytes

Cells that produce antibodies to neutralize antigens.

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T Lymphocytes

Cells that recognize antigens and help activate immune responses.

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CD8+ T Lymphocytes

Cytotoxic T cells that kill infected cells harboring microbes.

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Immune System Function

The primary role is to prevent and eradicate infections.

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Central Immune Organs

Organs where lymphocytes are produced and mature; includes bone marrow and thymus.

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Peripheral Immune Organs

Sites where immune cells respond to antigens; includes spleen and lymph nodes.

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Antigen Presentation

The process where cells display antigen to T-cells to activate them.

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Bone Marrow

The primary site for stem cell production of blood and immune cells.

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Thymus

An organ where T-cells mature and learn their functions.

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Spleen

An organ that filters blood and removes old red blood cells and pathogens.

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Lymph Nodes

Locations where immune cells gather to respond to pathogens in lymph.

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Granulocytes

A type of white blood cell that contains cytoplasmic granules filled with mediators.

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Mast Cells

Cells that release histamine and other mediators during allergic reactions.

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Immune Response Activation

The action of immune cells responding to a pathogen or infection.

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Stem Cells

Undifferentiated cells in the bone marrow capable of becoming various blood cells.

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Infectious Agents

Pathogens such as bacteria, viruses, and parasites that can cause disease.

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Activation of Immune Cells

The crucial step where immune cells respond to an antigen.

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Natural Killer Cells

A type of lymphocyte that kills infected or stressed cells.

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Cytokines

Soluble proteins that mediate inflammation and cell communication.

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Interleukins

A subtype of cytokines produced mainly by T-helper cells.

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Monokines

Cytokines produced exclusively by monocytes.

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Chemokines

A type of cytokine that mediates the movement of leukocytes.

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Complement System

A group of proteins that opsonize microbes and promote phagocyte recruitment.

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Opsonization

The process of marking pathogens for destruction by phagocytes.

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Immunoglobulin

Proteins synthesized by B lymphocytes that act as antibodies.

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T-helper cells

A type of T cell that assists other immune cells by releasing cytokines.

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Membrane-bound antibodies

Antibodies that serve as receptors on the surface of B lymphocytes.

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Secreted antibodies

Antibodies released into body fluids to neutralize threats.

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Apoptosis

Programmed cell death, an important process in the immune response.

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Components of Immune System

Cells, tissues, and molecules that mediate immune responses.

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Function of Immune Cells

To identify and eliminate foreign invaders like pathogens.

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Immune System Resistance

The ability to prevent or fight off disease, especially infections.

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Infectious Microbes

Microorganisms such as bacteria and viruses that cause disease.

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Coordinated Immune Response

The strategic reaction involving multiple immune cells to combat pathogens.

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Study of Immunology

The scientific examination of the immune system and its functions.

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Resistance to Infectious Disease

Immunity that specifically combats infections caused by pathogens.

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Role of Immune Cells

To recognize and respond to harmful substances and pathogens.

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Neutrophils

Blood cells that ingest and kill microbes during infections.

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Monocytes

Large blood cells that become macrophages and ingest pathogens.

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Helper T Lymphocytes

T cells that produce cytokines to activate other immune cells.

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Antigen Recognition

The process where T lymphocytes recognize protein fragments on infected cells.

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Cytotoxic T Lymphocytes (CTLs)

T cells that destroy infected cells by killing them directly.

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Function of Immune System

To prevent or eradicate infections.

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Naive Immune Cells

Immune cells that have not yet encountered an antigen.

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Removal of Old RBCs

Process by which the spleen eliminates aged red blood cells.

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Immune Cell Response

The coordinated reaction of immune cells to a pathogen.

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Lymphokines

Cytokines produced by lymphocytes that modulate immune responses.

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Interferons

Proteins involved in the immune response to viral infections.

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Dendritic Cells

Immune cells that process antigens and present them to T-cells.

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Nutritional Immunology

A field studying how nutrition impacts immune function.

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Immune Cells

Cells that play crucial roles in defending the body against infections and other diseases.

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