Multiple Choice Hard II

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Which of the following lipoglycopeptides has the highest volume of distribution?

Oritavancin

Which of the following is NOT a Gram-negative anaerobic activity of linezolid?

Prevotella

Which of the following is NOT a potential adverse drug reaction (ADR) of daptomycin?

LFT elevations

Which of the following organisms is linezolid NOT active against?

<p>Nocardia spp.</p> Signup and view all the answers

Which drug has a higher bioavailability, Linezolid or Clindamycin?

<p>The text does not provide this information</p> Signup and view all the answers

Which drug is primarily metabolized by the liver, Linezolid or Clindamycin?

<p>Both drugs are primarily metabolized by the liver</p> Signup and view all the answers

Which drug has a longer half-life, Linezolid or Clindamycin?

<p>The text does not provide this information</p> Signup and view all the answers

Which drug has activity against Toxoplasma gondii and is used in combination with pyrimethamine to treat toxoplasmosis?

<p>Clindamycin</p> Signup and view all the answers

Which type of bacteria is Lefamulin NOT active against?

<p>E. faecalis</p> Signup and view all the answers

Which type of bacteria does Lefamulin have good activity against?

<p>Gram negative organisms associated with community acquired pneumonia</p> Signup and view all the answers

Which drug is contraindicated with Lefamulin due to increased concentrations?

<p>Alprazolam</p> Signup and view all the answers

Which adverse effect is NOT associated with Lefamulin?

<p>Hepatic impairment</p> Signup and view all the answers

Which type of immunity is characterized by physical barriers, phagocytes, and strategically pre-deployed proteins?

<p>Innate immunity</p> Signup and view all the answers

Which type of immunity evolves and adapts against invading pathogens and is divided into humoral and cellular responses?

<p>Adaptive immunity</p> Signup and view all the answers

Which type of immunity is characterized by soluble factors such as lysozymes, complement, C-reactive protein, and interferons?

<p>Innate immunity</p> Signup and view all the answers

Which type of immunity is primarily responsible for forming barriers against an outside environment, such as the skin and lining of the respiratory, gastrointestinal, and genitourinary tracts?

<p>Innate immunity</p> Signup and view all the answers

Which one of the following is true about Neutrophils?

<p>Neutrophils are responsible for defense against bacteria and fungi.</p> Signup and view all the answers

What is the main role of Vancomycin in the treatment of Gram-positive infections?

<p>Inhibition of late cell wall synthesis</p> Signup and view all the answers

What is the recommended dosing target for Vancomycin?

<p>AUC/MIC = 400-600</p> Signup and view all the answers

What is the most common side effect of Vancomycin?

<p>Infusion-related reaction</p> Signup and view all the answers

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