Cytokines and Interleukins in Immune Response
17 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which cells play a key role in establishing peripheral tolerance to a wide variety of self-antigens, allergens, tumor antigens, transplant antigens, and infectious agents?

  • T Regulatory Cells (correct)
  • Th1 cells
  • B cells
  • CD8+T cells

    • What is the major effect of IL-10?

  • Induces the production of MHC-II on B cells
  • Stimulates CD8+T cells
  • Enhances antigen presentation by macrophages and dendritic cells
  • Inhibits IFN-Y production via the suppression of IL-12 synthesis (correct)

    • Where are Tregs (T Regulatory Cells) selected?

  • Lymph nodes
  • Spleen
  • Bone marrow
  • Thymus (correct)

    • What does IL-10 inhibit?

    <p>Antigen presentation by macrophages and dendritic cells</p> Signup and view all the answers

    Which cells produce Interleukin-10 (IL-10)?

    <p>CD8+T cells</p> Signup and view all the answers

    Which cytokine production is suppressed by IL-10?

    <p>IFN-Y</p> Signup and view all the answers

    What is the role of T Regulatory Cells in transplanted tissue?

    <p>Suppress the immune response against the graft</p> Signup and view all the answers

    How does IFN-Y affect antigen presentation by antigen-presenting cells?

    <p>Stimulates antigen presentation by MHC I and MHC II molecules</p> Signup and view all the answers

    What is the role of IL-12 in relation to natural killer (NK) cells?

    <p>Increases the cytolytic ability of NK cells</p> Signup and view all the answers

    What is the impact of IL-2 secretion by Th1 cells on T-cell growth and differentiation?

    <p>Drives the growth and differentiation of T and B cells</p> Signup and view all the answers

    How do IL-2 and IFN-Y contribute to the development of Th1 cells?

    <p>Induce the development of Th1 cells</p> Signup and view all the answers

    What are the actions of Th1 cells in relation to macrophage activation and hypersensitivity?

    <p>Induces macrophage activation and delayed type hypersensitivity</p> Signup and view all the answers

    Which cells does IL-2 activate to proliferate and generate IgG1 and IgE producing cells?

    <p>Th2 cells</p> Signup and view all the answers

    What is the primary responsibility of Th2 cells in immunity?

    <p>Antibody-mediated immunity</p> Signup and view all the answers

    How does IL-4 influence the immune response in relation to Th2 cells?

    <p>Regulates Th2 immune activities and drives antibody responses</p> Signup and view all the answers

    What effect does IL-4 have on naïve T cells in terms of Th2 cell generation?

    <p>Turns on genes that generate Th2 cells and turns off genes that promote Th1 cells</p> Signup and view all the answers

    What immune responses are regulated by Th2 cells?

    <p>Regulates many aspects of the immune response</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser