Podcast
Questions and Answers
Which cells play a key role in establishing peripheral tolerance to a wide variety of self-antigens, allergens, tumor antigens, transplant antigens, and infectious agents?
Which cells play a key role in establishing peripheral tolerance to a wide variety of self-antigens, allergens, tumor antigens, transplant antigens, and infectious agents?
- T Regulatory Cells (correct)
- Th1 cells
- B cells
- CD8+T cells
What is the major effect of IL-10?
What is the major effect of IL-10?
- Induces the production of MHC-II on B cells
- Stimulates CD8+T cells
- Enhances antigen presentation by macrophages and dendritic cells
- Inhibits IFN-Y production via the suppression of IL-12 synthesis (correct)
Where are Tregs (T Regulatory Cells) selected?
Where are Tregs (T Regulatory Cells) selected?
- Lymph nodes
- Spleen
- Bone marrow
- Thymus (correct)
What does IL-10 inhibit?
What does IL-10 inhibit?
Which cells produce Interleukin-10 (IL-10)?
Which cells produce Interleukin-10 (IL-10)?
Which cytokine production is suppressed by IL-10?
Which cytokine production is suppressed by IL-10?
What is the role of T Regulatory Cells in transplanted tissue?
What is the role of T Regulatory Cells in transplanted tissue?
How does IFN-Y affect antigen presentation by antigen-presenting cells?
How does IFN-Y affect antigen presentation by antigen-presenting cells?
What is the role of IL-12 in relation to natural killer (NK) cells?
What is the role of IL-12 in relation to natural killer (NK) cells?
What is the impact of IL-2 secretion by Th1 cells on T-cell growth and differentiation?
What is the impact of IL-2 secretion by Th1 cells on T-cell growth and differentiation?
How do IL-2 and IFN-Y contribute to the development of Th1 cells?
How do IL-2 and IFN-Y contribute to the development of Th1 cells?
What are the actions of Th1 cells in relation to macrophage activation and hypersensitivity?
What are the actions of Th1 cells in relation to macrophage activation and hypersensitivity?
Which cells does IL-2 activate to proliferate and generate IgG1 and IgE producing cells?
Which cells does IL-2 activate to proliferate and generate IgG1 and IgE producing cells?
What is the primary responsibility of Th2 cells in immunity?
What is the primary responsibility of Th2 cells in immunity?
How does IL-4 influence the immune response in relation to Th2 cells?
How does IL-4 influence the immune response in relation to Th2 cells?
What effect does IL-4 have on naïve T cells in terms of Th2 cell generation?
What effect does IL-4 have on naïve T cells in terms of Th2 cell generation?
What immune responses are regulated by Th2 cells?
What immune responses are regulated by Th2 cells?
