Cytokines and Innate Immunity Quiz
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Questions and Answers

Which of the following cells are the principal sources of cytokines in innate immunity?

  • B cells
  • Helper T lymphocytes
  • Dendritic cells, macrophages, and mast cells (correct)
  • Epithelial cells

    • Which of the following is not a powerful stimulus for cytokine secretion by macrophages and dendritic cells?

  • Recognition of host cells (correct)
  • Recognition of bacterial cell wall components such as LPS and peptidoglycan
  • Recognition of microbes
  • Recognition of microbial nucleic acids

    • What is the function of cytokines in the immune system?

  • To communicate between leukocytes and other cells (correct)
  • To produce antibodies
  • To mediate cellular reactions of adaptive immunity
  • To destroy microbes

    • Which cytokines are involved in recruiting blood neutrophils and monocytes to sites of infection?

    <p>Tumor necrosis factor (TNF)</p> Signup and view all the answers

    What is the role of type I IFNs in viral infections?

    <p>They prevent spread of the infection to uninfected cells</p> Signup and view all the answers

    What is the defining feature of septic shock?

    <p>Low blood pressure</p> Signup and view all the answers

    Which cytokine is responsible for inducing fever by acting on the hypothalamus?

    <p>Interleukin-1 (IL-1)</p> Signup and view all the answers

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