Adaptive vs. Innate Immunity: Cytokines and Immune Communication

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Questions and Answers

What is the main focus of autoimmune diseases?

  • Targeting the immune system
  • Protecting the organs
  • Attacking infectious agents
  • Damaging tissues of the body (correct)

Which type of immunity is nonspecific and older in evolutionary terms?

  • Granulocyte immunity
  • Adaptive immunity
  • Lymphocytic immunity
  • Innate immunity (correct)

What is the role of lymphocytes and antigen-presenting cells (APCs) in adaptive immunity?

  • Mediating innate immunity
  • Recognizing specific microbial invaders (correct)
  • Maintaining nonspecific defenses
  • Producing memory cells

Which cells are involved in mediating innate immunity?

<p>Granulocytes and leukocytes (C)</p> Signup and view all the answers

What is the function of memory cells in adaptive immunity?

<p>Providing a rapid response upon recurring infection (B)</p> Signup and view all the answers

Where are lymphocytes and antigen-presenting cells (APCs) distributed in the body?

<p>Throughout different tissues in the body (D)</p> Signup and view all the answers

What does innate immunity focus on defending against?

<p>Non-specific threats (C)</p> Signup and view all the answers

'Adaptive immunity produces _ cells that permit a rapid response if a specific microbe appears again.' Fill in the blank.

<p>'Memory' (D)</p> Signup and view all the answers

Where do lymphocytes primarily undergo activation and proliferation?

<p>Secondary lymphoid organs (C)</p> Signup and view all the answers

What is the function of Toll-like receptors (TLRs) in the immune system?

<p>Recognize and bind surface components of invaders (A)</p> Signup and view all the answers

Which of the following is a characteristic of innate immunity?

<p>Acts as a physical barrier against infections (D)</p> Signup and view all the answers

What role do natural killer (NK) cells play in immunity?

<p>Destroy unhealthy host cells (C)</p> Signup and view all the answers

Which enzyme hydrolyzes bacterial cell wall components to kill bacterial cells?

<p>Lysozyme (A)</p> Signup and view all the answers

Why do some pathogenic bacteria avoid phagocytosis by granulocytes and macrophages?

<p>By covering their cell walls with a capsule (A)</p> Signup and view all the answers

What is the main function of complement activation by antigen-antibody complexes?

<p>Rupture membranes of invading cells (A)</p> Signup and view all the answers

How does opsonization contribute to the immune response?

<p>It increases the efficiency of phagocytosis (A)</p> Signup and view all the answers

What is the role of NK cells in the immune response?

<p>Recognize antigens on infected cells and kill them (D)</p> Signup and view all the answers

Which type of antibodies bind receptors for complement activation?

<p>IgG and IgM (A)</p> Signup and view all the answers

What is the primary source of complement system proteins?

<p>Liver (B)</p> Signup and view all the answers

How do antibodies optimize innate immunity through opsonization?

<p>By enhancing phagocytosis efficiency (C)</p> Signup and view all the answers

What happens when NK cells are activated?

<p>They kill virus-infected cells (D)</p> Signup and view all the answers

How do complement components help in the immune response?

<p>Rupturing membranes, clumping cells, and activating leukocytes (B)</p> Signup and view all the answers

What is the main function of cytokines in the immune system?

<p>Stimulate growth in T lymphocytes and NK cells (B)</p> Signup and view all the answers

Which statement accurately describes cytokines?

<p>Coordinate both innate and adaptive immune responses. (C)</p> Signup and view all the answers

What is the primary role of antibodies in the immune system?

<p>Interact specifically with antigenic determinants (C)</p> Signup and view all the answers

Which cytokine is responsible for eosinophil proliferation, differentiation, and activation?

<p>IL-5 (A)</p> Signup and view all the answers

What is the function of GM-CSF and M-CSF cytokines?

<p>Promote growth and differentiation of leukocyte progenitor cells (A)</p> Signup and view all the answers

In what type of immunity do antibodies primarily play a role?

<p>Adaptive immunity (C)</p> Signup and view all the answers

Which region of the immunoglobulin molecules is recognized by cell surface receptors on basophils and mast cells?

<p>Constant Fc region (C)</p> Signup and view all the answers

What component of immunoglobulins makes up an antibody's antigen-binding site?

<p>Variable region (A)</p> Signup and view all the answers

Which class of antibodies is the most abundant in blood?

<p>IgG (C)</p> Signup and view all the answers

Which immunoglobulin class crosses the placental barrier into the fetal circulation, conferring passive immunity to the newborn?

<p>IgG (A)</p> Signup and view all the answers

Which class of antibodies is mainly produced in an initial response to an antigen?

<p>IgM (A)</p> Signup and view all the answers

Which immunoglobulin class is bound at its Fc region to receptors on mast cells and basophils?

<p>IgE (D)</p> Signup and view all the answers

Which class of antibodies is least abundant in plasma and acts as an antigen receptor on B lymphocytes?

<p>IgD (C)</p> Signup and view all the answers

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