Adaptive vs. Innate Immunity: Cytokines and Immune Communication
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Questions and Answers

What is the main focus of autoimmune diseases?

  • Targeting the immune system
  • Protecting the organs
  • Attacking infectious agents
  • Damaging tissues of the body (correct)
  • Which type of immunity is nonspecific and older in evolutionary terms?

  • Granulocyte immunity
  • Adaptive immunity
  • Lymphocytic immunity
  • Innate immunity (correct)
  • What is the role of lymphocytes and antigen-presenting cells (APCs) in adaptive immunity?

  • Mediating innate immunity
  • Recognizing specific microbial invaders (correct)
  • Maintaining nonspecific defenses
  • Producing memory cells
  • Which cells are involved in mediating innate immunity?

    <p>Granulocytes and leukocytes</p> Signup and view all the answers

    What is the function of memory cells in adaptive immunity?

    <p>Providing a rapid response upon recurring infection</p> Signup and view all the answers

    Where are lymphocytes and antigen-presenting cells (APCs) distributed in the body?

    <p>Throughout different tissues in the body</p> Signup and view all the answers

    What does innate immunity focus on defending against?

    <p>Non-specific threats</p> Signup and view all the answers

    'Adaptive immunity produces _ cells that permit a rapid response if a specific microbe appears again.' Fill in the blank.

    <p>'Memory'</p> Signup and view all the answers

    Where do lymphocytes primarily undergo activation and proliferation?

    <p>Secondary lymphoid organs</p> Signup and view all the answers

    What is the function of Toll-like receptors (TLRs) in the immune system?

    <p>Recognize and bind surface components of invaders</p> Signup and view all the answers

    Which of the following is a characteristic of innate immunity?

    <p>Acts as a physical barrier against infections</p> Signup and view all the answers

    What role do natural killer (NK) cells play in immunity?

    <p>Destroy unhealthy host cells</p> Signup and view all the answers

    Which enzyme hydrolyzes bacterial cell wall components to kill bacterial cells?

    <p>Lysozyme</p> Signup and view all the answers

    Why do some pathogenic bacteria avoid phagocytosis by granulocytes and macrophages?

    <p>By covering their cell walls with a capsule</p> Signup and view all the answers

    What is the main function of complement activation by antigen-antibody complexes?

    <p>Rupture membranes of invading cells</p> Signup and view all the answers

    How does opsonization contribute to the immune response?

    <p>It increases the efficiency of phagocytosis</p> Signup and view all the answers

    What is the role of NK cells in the immune response?

    <p>Recognize antigens on infected cells and kill them</p> Signup and view all the answers

    Which type of antibodies bind receptors for complement activation?

    <p>IgG and IgM</p> Signup and view all the answers

    What is the primary source of complement system proteins?

    <p>Liver</p> Signup and view all the answers

    How do antibodies optimize innate immunity through opsonization?

    <p>By enhancing phagocytosis efficiency</p> Signup and view all the answers

    What happens when NK cells are activated?

    <p>They kill virus-infected cells</p> Signup and view all the answers

    How do complement components help in the immune response?

    <p>Rupturing membranes, clumping cells, and activating leukocytes</p> Signup and view all the answers

    What is the main function of cytokines in the immune system?

    <p>Stimulate growth in T lymphocytes and NK cells</p> Signup and view all the answers

    Which statement accurately describes cytokines?

    <p>Coordinate both innate and adaptive immune responses.</p> Signup and view all the answers

    What is the primary role of antibodies in the immune system?

    <p>Interact specifically with antigenic determinants</p> Signup and view all the answers

    Which cytokine is responsible for eosinophil proliferation, differentiation, and activation?

    <p>IL-5</p> Signup and view all the answers

    What is the function of GM-CSF and M-CSF cytokines?

    <p>Promote growth and differentiation of leukocyte progenitor cells</p> Signup and view all the answers

    In what type of immunity do antibodies primarily play a role?

    <p>Adaptive immunity</p> Signup and view all the answers

    Which region of the immunoglobulin molecules is recognized by cell surface receptors on basophils and mast cells?

    <p>Constant Fc region</p> Signup and view all the answers

    What component of immunoglobulins makes up an antibody's antigen-binding site?

    <p>Variable region</p> Signup and view all the answers

    Which class of antibodies is the most abundant in blood?

    <p>IgG</p> Signup and view all the answers

    Which immunoglobulin class crosses the placental barrier into the fetal circulation, conferring passive immunity to the newborn?

    <p>IgG</p> Signup and view all the answers

    Which class of antibodies is mainly produced in an initial response to an antigen?

    <p>IgM</p> Signup and view all the answers

    Which immunoglobulin class is bound at its Fc region to receptors on mast cells and basophils?

    <p>IgE</p> Signup and view all the answers

    Which class of antibodies is least abundant in plasma and acts as an antigen receptor on B lymphocytes?

    <p>IgD</p> Signup and view all the answers

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