Cystic Fibrosis: Clinical Manifestations and Complications

Play an AI-generated podcast conversation about this lesson

What may trigger insulin resistance in individuals with Cystic Fibrosis?

Impaired fertility and osteoporosis

Airway obstruction and mucus accumulation

Hearing loss and clubbing

Infections and corticosteroid use (correct)

What is a common cause of infertility in men with Cystic Fibrosis?

Viscid cervical secretions

Complete sterility in at least 97% of cases (correct)

Airway obstruction and infection

Osteoporosis and malabsorption of nutrients

What is a potential side effect of long-term use of mycin group of drugs in Cystic Fibrosis patients?

Insulin resistance

Hearing loss (correct)

Respiratory rate increase

Clubbing and osteoporosis

What is a characteristic feature of clubbing in Cystic Fibrosis patients?

Widening of the tips of the fingers due to chronically low blood levels of oxygen Signup and view all the answers

Why is it essential to perform regular DEXA scans in Cystic Fibrosis patients?

To measure bone density and prevent osteoporosis Signup and view all the answers

What is a reason for impaired fertility in women with Cystic Fibrosis?

Viscid cervical secretions Signup and view all the answers

What is the primary goal of respiratory physiotherapy in the treatment of CF patients?

To remove mucus from the lungs Signup and view all the answers

What is the recommended caloric intake for infants with CF?

200kcal/kg Signup and view all the answers

Why are enteric-coated enzyme microspheres used in CF treatment?

To withstand stomach acidity and release enzymes in the duodenum Signup and view all the answers

What is the recommended percentage of protein in the diet of CF patients?

30-35% Signup and view all the answers

Why is it essential to supplement fat-soluble vitamins in CF patients?

Due to malabsorption of fat-soluble vitamins Signup and view all the answers

Why is sodium intake crucial in CF patients?

Due to higher sodium losses in sweat Signup and view all the answers

What is the location of the defective gene that causes Cystic Fibrosis?

The long arm of chromosome 7 Signup and view all the answers

What is the effect of thick mucus in the intestine in individuals with Cystic Fibrosis?

Reduced release of digestive enzymes and bicarbonate Signup and view all the answers

What is the term for the obstruction of stools in the first 1-2 weeks of life in infants with Cystic Fibrosis?

Meconium ileus Signup and view all the answers

What is the name of the disease that can occur in individuals with Cystic Fibrosis due to pancreatic blockage?

Diabetes Mellitus Signup and view all the answers

What is the term for the elevated levels of Na, Cl, and electrolytes in the sweat of individuals with Cystic Fibrosis?

Abnormally high sweat concentration in electrolytes Signup and view all the answers

What is the inheritance pattern of Cystic Fibrosis?

Autosomal recessive Signup and view all the answers