Crude Drugs: Organized and Unorganized

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Questions and Answers

How are crude drugs defined regarding changes to their chemical composition?

  • Substances that have been chemically synthesized for direct use as drugs.
  • Substances that are chemically altered to remove any toxic components before being used as a drug.
  • Substances that have undergone complete chemical transformation to enhance their potency.
  • Substances that have not been changed or modified in their chemical composition, used directly or indirectly as a drug. (correct)

What are the two primary categories into which crude drugs of natural origin are divided?

  • Processed and unprocessed crude drugs
  • Organized and unorganized crude drugs (correct)
  • Inorganic and synthetic crude drugs
  • Synthetic and organic crude drugs

Which characteristic defines organized crude drugs?

  • Requiring extensive microscopical studies for identification
  • Exclusively derived from animal sources
  • Presence of cellular organization and anatomical features (correct)
  • Lack of distinct morphological or anatomical features

If you were examining a sample of bark under a microscope, which type of crude drug would it most likely be classified as?

<p>Organized crude drug (A)</p> Signup and view all the answers

What is a key feature of unorganized crude drugs that differentiates them from organized drugs?

<p>They do not have morphological or anatomical organization. (D)</p> Signup and view all the answers

Which of the following is an example of an unorganized crude drug?

<p>Gums (A)</p> Signup and view all the answers

What are the three key characteristics a system of classification of drugs should possess?

<p>Simple, easy to use, and free from confusion and ambiguities (C)</p> Signup and view all the answers

In the context of studying individual drugs, what is essential to adopt for effective understanding?

<p>A system of classification of drugs (D)</p> Signup and view all the answers

What is the fundamental principle behind alphabetical classification of crude drugs?

<p>Arranging drugs in alphabetical order of their Latin and English names (C)</p> Signup and view all the answers

Which characteristic makes alphabetical classification suitable for disconnected items?

<p>Its simplicity and ease of use (B)</p> Signup and view all the answers

What is the basis for classifying crude drugs in taxonomical classification?

<p>Their arrangement according to kingdom, subkingdom, division, class, order, family, genus, and species (A)</p> Signup and view all the answers

If you are classifying a crude drug based on its family and genus, which classification method are you using?

<p>Taxonomical classification (D)</p> Signup and view all the answers

What is the organizing principle in morphological classification of drugs?

<p>Arrangement according to the plant or animal part used as a drug (C)</p> Signup and view all the answers

When classifying drugs based on whether they are leaves, roots, or stems, which classification method is being used?

<p>Morphological classification (B)</p> Signup and view all the answers

How are drugs organized in pharmacological classification?

<p>Based on their pharmacological or therapeutic properties (B)</p> Signup and view all the answers

If you are grouping drugs together because they all act as diuretics, which classification method are you employing?

<p>Pharmacological classification (B)</p> Signup and view all the answers

What is the primary criterion for classifying crude drugs in chemical classification?

<p>Their active constituents or basic structure (A)</p> Signup and view all the answers

If several plants are grouped together because they all contain alkaloids, which classification method is being applied?

<p>Chemical classification (C)</p> Signup and view all the answers

In chemotaxonomical classification, what serves as the basis for classifying plants together?

<p>The presence of similar chemical compounds (D)</p> Signup and view all the answers

What does chemotaxonomy rely on to establish relationships between different plants?

<p>Similarity in chemical composition (B)</p> Signup and view all the answers

According to commercial classification, what is the primary basis for classifying medicinal plants?

<p>Their use in the commercial market (C)</p> Signup and view all the answers

Under commercial classification, what category would plants sold for treating diseases fall into?

<p>Medicinal plants (B)</p> Signup and view all the answers

In commercial classification, what is the primary distinction of 'aromatic plants'?

<p>They contain volatile oils and are used as flavoring agents, in perfumes, and cosmetic creams. (A)</p> Signup and view all the answers

Based on the provided text, what is the commercial application of insecticide plants?

<p>Used for killing insects, rodents, and fungi. (D)</p> Signup and view all the answers

What is a practical example of morphological classification in the context of natural products?

<p>Categorizing drugs according to whether they are derived from roots, stems, or leaves (D)</p> Signup and view all the answers

Which of the following is an example of how the property of being 'anti-cancer' would be used in drug classification?

<p>Pharmacological classification based on therapeutic effect (C)</p> Signup and view all the answers

Which of the following features would be most important when classifying a plant using taxonomical classification?

<p>The plant's family, genus, and species (D)</p> Signup and view all the answers

Why is it important for a system classifying natural products to be free of ambiguities?

<p>To avoid inconsistencies and ensure everyone classifies drugs the same way (C)</p> Signup and view all the answers

If a new drug is found to contain a novel saponin structure, which classification method would best categorize it initially?

<p>Chemical, based on the saponin structure (A)</p> Signup and view all the answers

If a researcher wants to study if certain metabolic products are closely related between species, which classification method is most relevant?

<p>Chemotaxonomical, as it illustrates similarity of taxa (B)</p> Signup and view all the answers

If two plants are grouped because the both produce morphine, but have very different physical characteristics, what type of classification would allow this?

<p>Chemical, based similar active components (B)</p> Signup and view all the answers

Which of the following properties would make plant extracts useful as 'Aromatic Plants' in the commercial classification system?

<p>High concentration of oils (B)</p> Signup and view all the answers

Which of the following plants are most helpful in flavoring, perfumes, and cosmetics?

<p>Aromatic plants (B)</p> Signup and view all the answers

When classifying plants commercially, what makes them useful in creating beverages?

<p>They have flavoring components, such as cocao (D)</p> Signup and view all the answers

How do 'organized crude drugs' differ significantly from 'unorganized crude drugs'?

<p>Organized crude drugs have cellular organization, unlike unorganized (B)</p> Signup and view all the answers

If you need to arrange a series of natural products in a logical order using the simplest classification system, which would you choose?

<p>Alphabetical (C)</p> Signup and view all the answers

If a series of plants are found to have analgesic properties, but come from separate genera or species, hoe would we most easily categorize them?

<p>Classifying based on pharmacology (D)</p> Signup and view all the answers

What is the primary use of classifying an 'Insecticide Plant' via commercial guidelines?

<p>To find plants that possess insect-killing properties (A)</p> Signup and view all the answers

Flashcards

What are Crude drugs?

Substances used directly or indirectly as a drug, unchanged or unmodified in chemical composition.

What are organized crude drugs?

Crude drugs with cellular organization, like plant parts.

What are unorganized crude drugs?

Crude drugs lacking cellular organization; plant, animal, or mineral products.

What is drug classification?

Arrangement of drugs for study, ensuring simplicity and clarity.

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What is alphabetical classification?

Arranging drugs alphabetically by Latin or English names.

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What is taxonomic classification?

Classifying drugs by kingdom, phylum, class, order, family, genus, and species.

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What is morphological classification?

Arranging drugs by plant or animal part used.

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What is pharmacological classification?

Grouping drugs by their pharmacological or therapeutic effect.

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What is chemical classification?

Classifying drugs based on their active chemical constituents.

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What is chemotaxonomical classification?

Classification based on chemical similarity within a taxon.

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What are medicinal plants?

Plants sold for treating diseases.

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What are condiments/spices?

Plants used to flavor food.

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What are aromatic plants?

Plants used for their scent or flavor.

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What are insecticide plants?

Plants used to kill insects, rodents or fungi.

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What are beverage plants?

Plants used to make tea, coffee, and cacao.

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Study Notes

  • Crude drugs are substances used directly or indirectly as drugs
  • Crude drugs are not changed or modified in their chemical composition

Categories of Crude Drugs

  • Crude drugs of natural origin are divided into two main categories
  • These categories are organized crude drugs and unorganized crude drugs

Organized Drugs

  • Organized drugs have cellular organization with anatomical features
  • Organized drugs are mostly crude drugs from plant sources
  • Morphological plant parts or entire plants are examples of organized drugs
  • Examples include leaves, seeds, bark, and flowers

Unorganized Drugs

  • Unorganized drugs lack morphological or anatomical organization
  • Unorganized drugs are products that come directly to market from plants, animals, or minerals, however they do not require microscopical studies
  • Examples include plant exudates like gums, oleogums, oleogumresins, plant lattices like opium, aloetic juices like aloes or dried extracts of agar, essential oils, fixed oils, fats, and waxes

Classification of Crude Drugs

  • Studying individual drugs requires a specific arrangement sequence, termed a system of classification
  • A classification method needs to be simple, easy to use, and free from confusion and ambiguities

Types of Drug Classification

  • Alphabetical
  • Morphological
  • Taxonomical
  • Pharmacological
  • Chemical
  • Chemo taxonomical
  • Sero-taxonomical

Alphabetical Classification

  • Alphabetical classification is the simplest method of classifying disconnected items
  • Crude drugs are arranged alphabetically by their Latin and English names
  • Some pharmacopoeias, dictionaries, and reference books use this system
  • Examples include British Pharmacopoeia, British Herbal Pharmacopoeia, United States Pharmacopoeia, National Formulary, British Pharmaceutical Codex, and European Pharmacopoeia

Taxonomical Classification

  • Crude drugs are classified according to:
    • Kingdom
    • Subkingdom
    • Division
    • Class
    • Order
    • Family
    • Genus
    • Species

Morphological Classification

  • Drugs are organized by morphological or external characteristics of plant or animal parts
  • Classification is based on the plant part used (leaves, roots, stem, etc.)
  • It applies to both organized and unorganized drugs

Pharmacological Classification

  • Drugs are grouped based on their pharmacological or therapeutic effects
  • For example:
    • Cardiotonics like Digitalis and red squill treats heart failure
    • Laxatives like Senna, Castor oil, and Aloe relieve constipation
    • Sedatives or narcotics such as Papaver and Datura induce calming or sleep
    • Carminatives like Peppermint, Spearmint and Anise relieve flatulence
    • Antirheumatics such as Salix and black mustard alleviate symptoms of rheumatism
    • Nutrients like Citrus, Allium and Garlic provide essential dietary elements
    • Anti cancer drugs like Vincristine and vinblastin are derived from(Vinca rosea)
    • CNS stimulants such as caffeine and theophyllin are derived from tea, coffee and cacao.
    • Narcotic analgesics suchas morphine are derived from Opium
    • Anticholinergics like Atropine and Hyoscine are derived from Datura and Belladonna.
    • Cholinergics like Pilocarpine and muscarine stimulate the parasympathetic nervous system.
    • Adrenergics: Ephedrine stimulates the sympathetic nervous system.
    • Antiarrhythmics suchas Quinidine are derived from Cinchona
    • Antihypertensives :Reserpine lowers blood pressure
    • Diuretics: Xanthin derivatives( from tea and coffee) increase urine production
    • Hypolipedimics :Garlic lowers lipid levels
    • Astringents:Tannins(gall or pomegranate) constrict tissues
    • Antiseptics such as Eucalyptus oil, Thyme oil, and Eugenol prevent infection
    • Antiinfectives such as Antibiotics from moulds and Streptomyces, Antimalarials (quinine from Cinchona), Amoebicides(Emetine from Ipecac), Antihelmentics (Santonin from Achillia) combate infections

Chemical Classification

  • Crude drugs are classified by active constituents or basic structure
  • Plants contain various constituents like alkaloids, glycosides, tannin, carbohydrates, and saponins
  • Morphological or taxonomical characteristics aren't considered; plants grouped irrespective of these

Chemical constituents and Examples of their use.

  • Alkaloids: Cinchona, Datura, Vinca, Ipecac, Nux vomica
  • Glycosides: Senna, Aloa, Ginsing, Digitalis
  • Carbohydrates: Acacia, Tragacanth, Starch
  • Volatile Oils: Clove, Fennel, Cinnamon, Cumin
  • Resin and Resin Combinations: Benzoin, Tolu Balsam, Balsam of Peru
  • Tannins: Catechu, Tea
  • Enzymes: Caisin, Trypsin
  • Lipids: Beeswax, Cocoa butter, Lanolin

Chemotaxonomical Classification

  • Classification relies on the chemical similarity of a taxon
  • Classification is based on the relationship between constituents in various plants
  • Tropane alkaloids in Solanaceae serve as a chemotaxonomic marker

Commercial Classification of Plants

  • A system in which medicinal plants are classified based on commercial use
  • Medicinal Plants are sold for treating diseases
  • Condiments: White and black mustard; Spices: black pepper; Flavoring agents: cardamon; Coloring agents: Crocus (crocin)
  • Aromatic Plants contain volatile oils; employed as flavoring agents for food, in perfumes, and cosmetic creams
  • Insecticide Plants kill insects like prythrum; killing rodents like red squill; killing fungi like henna
  • Beverages come from medicinal plants like tea, coffee, cacao, and cola

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