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Corticosteroids in Acute Gout Management

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Corticosteroids in Acute Gout Management

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Questions and Answers

Which statement is correct regarding the use of corticosteroids in acute gout cases?

Corticosteroids are recommended as the first-line treatment for acute gout.

Corticosteroids should never be used in acute gout cases.

Corticosteroids are ineffective in treating coexistent systemic illness or marked inflammation.

Corticosteroids should be used when NSAIDs or colchicine are contraindicated or not tolerated. (correct)

In a randomized trial comparing prednisolone, indomethacin, and etodolac for acute gout, which statement is true?

Prednisolone 30 mg daily for 5 days and standard doses of indomethacin or etodolac were equally effective. (correct)

Prednisolone 30 mg daily for 5 days was less effective than standard doses of indomethacin or etodolac.

Prednisolone 30 mg daily for 5 days was more effective than standard doses of indomethacin or etodolac.

The trial did not compare the effectiveness of prednisolone, indomethacin, and etodolac.

If only one or two joints are affected in an acute gout attack, what is the recommended treatment according to the text?

Inject the affected joints with a corticosteroid and a local anesthetic. (correct)

Administer colchicine orally.

Administer high doses of NSAIDs immediately.

Inject the affected joints with a local anesthetic only.

What is the recommended duration of NSAID treatment for an acute gout attack if the patient is seen within the first 24 hours and has no history of NSAID intolerance?

3 days Signup and view all the answers

If an acute gout attack responds completely to an NSAID, how should the NSAID dose be adjusted according to the text?

The NSAID dose should be tapered off over several days to minimize recurrence. Signup and view all the answers

When are NSAIDs recommended as the first-line treatment for acute gout?

NSAIDs are recommended as the first-line treatment for acute gout, except for patients who are frail, aged, have a history of peptic ulcer disease, renal impairment, or are taking anticoagulants. Signup and view all the answers

Which of the following statements about indomethacin is correct?

The recommended dosage range is 50-200 mg per day, divided into 3-4 doses based on gout severity. Signup and view all the answers

What is the recommended strategy for preventing NSAID-related ulcers in patients at high risk?

All of the above are recommended strategies. Signup and view all the answers

Which of the following statements about colchicine is incorrect?

High doses of colchicine are more effective than lower doses in treating acute gout attacks. Signup and view all the answers

Which of the following statements regarding corticosteroids in gout treatment is true?

High-dose systemic corticosteroids or ACTH may precipitate an acute attack phase in gout due to their anti-inflammatory effect. Signup and view all the answers

Which of the following statements about combination therapy for acute gout management is incorrect?

Combination therapy is not recommended for patients with severe tophaceous gout or diuretic-induced gout. Signup and view all the answers

Which of the following statements regarding NSAID-related toxicities is correct?

Long-term use of NSAIDs can lead to renal insufficiency, particularly in patients with pre-existing risk factors. Signup and view all the answers