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Corticosteroids in Acute Gout Management

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12 Questions

Which statement is correct regarding the use of corticosteroids in acute gout cases?

Corticosteroids should be used when NSAIDs or colchicine are contraindicated or not tolerated.

In a randomized trial comparing prednisolone, indomethacin, and etodolac for acute gout, which statement is true?

Prednisolone 30 mg daily for 5 days and standard doses of indomethacin or etodolac were equally effective.

If only one or two joints are affected in an acute gout attack, what is the recommended treatment according to the text?

Inject the affected joints with a corticosteroid and a local anesthetic.

What is the recommended duration of NSAID treatment for an acute gout attack if the patient is seen within the first 24 hours and has no history of NSAID intolerance?

3 days

If an acute gout attack responds completely to an NSAID, how should the NSAID dose be adjusted according to the text?

The NSAID dose should be tapered off over several days to minimize recurrence.

When are NSAIDs recommended as the first-line treatment for acute gout?

NSAIDs are recommended as the first-line treatment for acute gout, except for patients who are frail, aged, have a history of peptic ulcer disease, renal impairment, or are taking anticoagulants.

Which of the following statements about indomethacin is correct?

The recommended dosage range is 50-200 mg per day, divided into 3-4 doses based on gout severity.

What is the recommended strategy for preventing NSAID-related ulcers in patients at high risk?

All of the above are recommended strategies.

Which of the following statements about colchicine is incorrect?

High doses of colchicine are more effective than lower doses in treating acute gout attacks.

Which of the following statements regarding corticosteroids in gout treatment is true?

High-dose systemic corticosteroids or ACTH may precipitate an acute attack phase in gout due to their anti-inflammatory effect.

Which of the following statements about combination therapy for acute gout management is incorrect?

Combination therapy is not recommended for patients with severe tophaceous gout or diuretic-induced gout.

Which of the following statements regarding NSAID-related toxicities is correct?

Long-term use of NSAIDs can lead to renal insufficiency, particularly in patients with pre-existing risk factors.

Learn about the use of corticosteroids in managing acute gout cases when NSAIDs or colchicine are not suitable. Discover their effectiveness in treating systemic illness or severe inflammation, including comparisons with standard treatments like indomethacin or etodolac. Explore the option of joint injections for localized gout management.

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