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Questions and Answers
Where do corticosteroids combine with receptors to form a macromolecular complex?
Where do corticosteroids combine with receptors to form a macromolecular complex?
Which of the following is secreted by the adrenal cortex?
Which of the following is secreted by the adrenal cortex?
Which of the following corticosteroids is long-acting?
Which of the following corticosteroids is long-acting?
How do corticosteroids affect acute inflammation?
How do corticosteroids affect acute inflammation?
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What is the main pharmacological action of corticosteroids on carbohydrates, protein, and fat metabolism?
What is the main pharmacological action of corticosteroids on carbohydrates, protein, and fat metabolism?
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Study Notes
Corticosteroids
- Corticosteroids combine with receptors to form a macromolecular complex in the cytoplasm of target cells.
Adrenal Cortex Secretion
- The adrenal cortex secretes corticosteroids, which include glucocorticoids and mineralocorticoids.
Long-Acting Corticosteroid
- Dexamethasone is a long-acting corticosteroid.
Anti-Inflammatory Effects
- Corticosteroids reduce acute inflammation by inhibiting the production of chemical mediators that promote inflammation, decreasing the permeability of blood vessels, and reducing the migration of white blood cells to the site of inflammation.
Metabolic Effects
- The main pharmacological action of corticosteroids is to stimulate the breakdown of protein and fat for energy production, increase glucose levels in the blood, and promote the storage of glycogen in the liver.
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Description
This quiz provides an overview of corticosteroids pharmacology, focusing on the adrenal cortex secretion, the HPA axis, and the molecular mechanism of action of corticosteroids.
