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Constrictive Pericarditis Overview and Causes
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Constrictive Pericarditis Overview and Causes

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Questions and Answers

What sound is characterized by a sudden cessation of blood flow into rigid ventricles during diastole?

  • S3 Heart Sound
  • S4 Heart Sound
  • Squawk Sign
  • Pericardial Knock (correct)

    • Kussmaul's sign indicates that jugular venous distension remains constant with inspiration.

    True

    Describe the characteristic change in blood pressure known as pulsus paradoxus.

    A decrease in systolic blood pressure by ≥10 mmHg during inspiration.

    A marked thickening of the ______ is observed in constrictive pericarditis.

    <p>pericardium</p> Signup and view all the answers

    Match the diagnostic findings to their significance in constrictive pericarditis:

    <p>Low QRS voltage = Electrocardiogram (ECG) finding Thickened pericardium = Echocardiogram finding Lateral view calcifications = Chest X-Ray finding Square root sign = Hemodynamic finding</p> Signup and view all the answers

    Which factor is NOT characteristic of constrictive pericarditis?

    <p>Elevated left ventricular pressures</p> Signup and view all the answers

    Constrictive pericarditis can present with an S3 or S4 heart sound.

    <p>False</p> Signup and view all the answers

    What is the primary goal of treating constrictive pericarditis?

    <p>Management of symptoms related to venous congestion.</p> Signup and view all the answers

    In constrictive pericarditis, the right and left ventricular diastolic pressures are approximately ______.

    <p>equal</p> Signup and view all the answers

    Which imaging technique is considered the key diagnostic tool for constrictive pericarditis?

    <p>Echocardiogram</p> Signup and view all the answers

    What is the primary characteristic of constrictive pericarditis?

    <p>Fibrous and inelastic pericardial sac</p> Signup and view all the answers

    Constrictive pericarditis can develop from a single episode of acute pericarditis.

    <p>False</p> Signup and view all the answers

    Name one infectious cause of constrictive pericarditis.

    <p>Mycobacterium tuberculosis</p> Signup and view all the answers

    Pitting edema is caused by fluid accumulation in the ______.

    <p>lower extremities</p> Signup and view all the answers

    Match the symptoms to their corresponding heart failure signs:

    <p>Jugular Venous Distension (JVD) = Right Heart Failure Hypotension = Left Heart Failure Hepatomegaly = Right Heart Failure Pulmonary congestion = Left Heart Failure</p> Signup and view all the answers

    Which of the following is NOT a cause of constrictive pericarditis?

    <p>Diabetes mellitus</p> Signup and view all the answers

    Kussmaul's sign is characterized by an increase in jugular venous pressure during inspiration.

    <p>False</p> Signup and view all the answers

    What is the primary clinical feature of constrictive pericarditis?

    <p>Right heart failure symptoms</p> Signup and view all the answers

    Chronic pericarditis with a fibrous sac can result in increased ______ pressure.

    <p>venous</p> Signup and view all the answers

    Which of the following is true about heart failure symptoms in constrictive pericarditis?

    <p>Right heart failure symptoms are more evident than left.</p> Signup and view all the answers

    What is a common clinical feature of constrictive pericarditis?

    <p>Jugular venous distension</p> Signup and view all the answers

    Constrictive pericarditis is characterized by a fibrous and elastic pericardial sac.

    <p>False</p> Signup and view all the answers

    Name one infectious cause of constrictive pericarditis.

    <p>Mycobacterium tuberculosis</p> Signup and view all the answers

    The inability to decrease jugular venous pressure upon inspiration is known as _____ sign.

    <p>Kussmaul's</p> Signup and view all the answers

    Match the following symptoms with their corresponding causes:

    <p>Hepatomegaly = Inferior vena cava back pressure Ascites = Fluid accumulation in the abdominal cavity Pitting Edema = Systemic congestion JVD = Superior vena cava pressure</p> Signup and view all the answers

    Which condition is a cause of constrictive pericarditis?

    <p>Lung cancer</p> Signup and view all the answers

    Chronic inflammation of the pericardium can be caused by radiation therapy.

    <p>True</p> Signup and view all the answers

    What signifies right heart failure in constrictive pericarditis?

    <p>Jugular venous distension</p> Signup and view all the answers

    Infections such as Coxsackie B and _____ may contribute to constrictive pericarditis.

    <p>SARS-CoV-2</p> Signup and view all the answers

    Which of the following is NOT a clinical sign of right heart failure?

    <p>Pulmonary congestion</p> Signup and view all the answers

    Which sign is associated with constrictive pericarditis that indicates fixed jugular venous pressure during inspiration?

    <p>Kussmaul's sign</p> Signup and view all the answers

    Pulsus paradoxus is commonly observed in restrictive cardiomyopathy.

    <p>False</p> Signup and view all the answers

    What is a common diagnostic imaging finding in constrictive pericarditis?

    <p>Thickened pericardium</p> Signup and view all the answers

    The diagnostic finding during catheterization that shows equal left and right ventricular end-diastolic pressures in constrictive pericarditis is known as the ______.

    <p>square root sign</p> Signup and view all the answers

    Match the following diagnostic tools with their findings related to constrictive pericarditis:

    <p>ECG = Low QRS voltage Chest X-Ray = Pericardial calcifications Echocardiogram = Septal bounce CT/MRI = Thickened pericardium</p> Signup and view all the answers

    Which of the following could lead to the development of constrictive pericarditis?

    <p>Tuberculosis</p> Signup and view all the answers

    In restrictive cardiomyopathy, patients typically present with Kussmaul's sign.

    <p>False</p> Signup and view all the answers

    What is the primary difference between constrictive pericarditis and restrictive cardiomyopathy regarding the origin of their issues?

    <p>Constrictive pericarditis involves the pericardium, while restrictive cardiomyopathy involves the myocardium.</p> Signup and view all the answers

    The treatment for constrictive pericarditis often includes _____ to relieve symptoms.

    <p>diuretics</p> Signup and view all the answers

    Which physical examination finding may suggest constrictive pericarditis?

    <p>Hepatojugular reflux</p> Signup and view all the answers

    Which of the following is a common infectious cause of constrictive pericarditis?

    <p>Mycobacterium tuberculosis</p> Signup and view all the answers

    Jugular venous pressure decreases upon inspiration in constrictive pericarditis.

    <p>False</p> Signup and view all the answers

    What clinical feature predominantly reflects right heart failure symptoms in constrictive pericarditis?

    <p>Jugular Venous Distension</p> Signup and view all the answers

    Chronic inflammation of the pericardium may be caused by ________ therapy.

    <p>radiation</p> Signup and view all the answers

    Match the following signs with their associated symptoms of heart failure:

    <p>JVD = Increased venous pressure Hepatomegaly = Fluid in the liver Ascites = Fluid in the abdominal cavity Pitting Edema = Fluid in lower extremities</p> Signup and view all the answers

    Which statement is true regarding constrictive pericarditis?

    <p>It is characterized by a fibrous and inelastic pericardial sac.</p> Signup and view all the answers

    Name one neoplastic cause of constrictive pericarditis.

    <p>Lung cancer</p> Signup and view all the answers

    Kussmaul's sign indicates a decrease in jugular venous pressure upon inspiration.

    <p>False</p> Signup and view all the answers

    Symptoms of right heart failure in constrictive pericarditis include _______ and edema.

    <p>hepatomegaly</p> Signup and view all the answers

    What effect does constrictive pericarditis have on stroke volume?

    <p>Decreases it</p> Signup and view all the answers

    Which of the following findings is most characteristic of constrictive pericarditis?

    <p>Septal bounce during inspiration</p> Signup and view all the answers

    Pulsus paradoxus is commonly observed in cases of restrictive cardiomyopathy.

    <p>False</p> Signup and view all the answers

    What is the typical shape of the pressure curve seen in the early diastole of patients with constrictive pericarditis?

    <p>Square root sign</p> Signup and view all the answers

    The presence of ______ indicates significant restriction in ventricular filling capacity during diastole in constrictive pericarditis.

    <p>pericardial knock</p> Signup and view all the answers

    Match the following diagnostic findings with their significance:

    <p>Low QRS voltage = Indicates pericardial thickening Pericardial calcifications = Commonly seen on chest X-ray Thickened pericardium = Key finding on echocardiogram Kussmaul's sign = Suggests impaired filling of right heart</p> Signup and view all the answers

    Which of the following is a common symptom associated with constrictive pericarditis?

    <p>Jugular venous distension</p> Signup and view all the answers

    Constrictive pericarditis primarily affects systolic function of the heart.

    <p>False</p> Signup and view all the answers

    Describe the relationship between right and left ventricular diastolic pressures in constrictive pericarditis.

    <p>Approximately equal</p> Signup and view all the answers

    In constrictive pericarditis, patients experience a drop in systolic blood pressure greater than or equal to ______ mmHg during inspiration.

    <p>10</p> Signup and view all the answers

    Match the following conditions to their characteristics:

    <p>Constrictive pericarditis = Rigid pericardium restricting heart filling Restrictive cardiomyopathy = Reduced myocardial compliance leading to filling issues Pericardial effusion = Fluid accumulation in the pericardial sac Heart failure = Result of either condition's impaired function</p> Signup and view all the answers

    What is the characteristic sound associated with constrictive pericarditis?

    <p>Pericardial knock</p> Signup and view all the answers

    In constrictive pericarditis, pulsus paradoxus is rarely observed.

    <p>False</p> Signup and view all the answers

    What unique pattern is seen in pressure curves during diastole in constrictive pericarditis?

    <p>Square root sign</p> Signup and view all the answers

    In constrictive pericarditis, the _______ indicates that right heart inflow increases during inspiration.

    <p>Kussmaul's sign</p> Signup and view all the answers

    Match the following symptoms with their corresponding findings related to constrictive pericarditis:

    <p>Jugular venous distension = Kussmaul's sign Pericardial knock = Restrictive filling Pulsus paradoxus = Systolic blood pressure drop during inspiration Square root sign = Unique pressure curve pattern</p> Signup and view all the answers

    Which diagnostic tool is considered key for diagnosing constrictive pericarditis?

    <p>Echocardiogram</p> Signup and view all the answers

    Name one of the main symptoms indicating fluid overload in constrictive pericarditis.

    <p>Hepatomegaly</p> Signup and view all the answers

    Chest X-ray findings can definitively distinguish between constrictive pericarditis and restrictive cardiomyopathy.

    <p>False</p> Signup and view all the answers

    Match the type of heart failure with its characteristic findings:

    <p>Constrictive Pericarditis = Kussmaul's sign Restrictive Cardiomyopathy = S3 or S4 heart sound Both conditions = Equal diastolic pressures in left and right ventricles Neither condition = Peripheral artery disease</p> Signup and view all the answers

    The initial treatment for symptoms of congestive heart failure in constrictive pericarditis often includes _______ restriction.

    <p>fluid</p> Signup and view all the answers

    What is a primary cause of constrictive pericarditis?

    <p>Viral infections</p> Signup and view all the answers

    Constrictive pericarditis results in reduced stroke volume and cardiac output.

    <p>True</p> Signup and view all the answers

    Name one autoimmune disorder that can lead to constrictive pericarditis.

    <p>Systemic lupus erythematosus</p> Signup and view all the answers

    Jugular venous distension (JVD) is a result of increased _____ pressure.

    <p>venous</p> Signup and view all the answers

    Match the following symptoms with their associated causes:

    <p>Hepatomegaly = Inferior vena cava pressure Ascites = Fluid accumulation in the abdominal cavity Pitting Edema = Systemic congestion Jugular Venous Distension = Superior vena cava pressure</p> Signup and view all the answers

    What sign indicates that jugular venous pressure does not decrease upon inspiration?

    <p>Kussmaul's Sign</p> Signup and view all the answers

    Constrictive pericarditis can develop from a single episode of acute pericarditis.

    <p>False</p> Signup and view all the answers

    Which imaging technique is key in diagnosing constrictive pericarditis?

    <p>Echocardiogram</p> Signup and view all the answers

    To relieve symptoms of constrictive pericarditis, the treatment often includes _____ procedures.

    <p>surgical</p> Signup and view all the answers

    Which of the following is NOT a symptom of right heart failure in constrictive pericarditis?

    <p>Hypotension</p> Signup and view all the answers

    Which sign indicates a decrease in systolic blood pressure by ≥10 mmHg during inspiration?

    <p>Pulsus paradoxus</p> Signup and view all the answers

    Constrictive pericarditis affects primarily the systolic function of the heart.

    <p>False</p> Signup and view all the answers

    What is the primary diagnostic tool for assessing constrictive pericarditis?

    <p>Echocardiogram</p> Signup and view all the answers

    In constrictive pericarditis, the pressure curves during early diastole show a unique ______ pattern.

    <p>dip and plateau</p> Signup and view all the answers

    Match the following clinical signs with their descriptions:

    <p>Kussmaul's sign = Increase in jugular venous pressure upon inspiration Pericardial knock = Distinct sound during ventricular diastole Pulsus paradoxus = Decrease in systolic blood pressure during inspiration Jugular venous distention = Visible swelling in the neck veins</p> Signup and view all the answers

    Which condition is least likely to present with thickening of the pericardium?

    <p>Restrictive cardiomyopathy</p> Signup and view all the answers

    Electrocardiogram (ECG) findings in constrictive pericarditis may include low QRS voltage.

    <p>True</p> Signup and view all the answers

    Name one common treatment strategy for managing symptoms of constrictive pericarditis.

    <p>Fluid restriction or diuretics</p> Signup and view all the answers

    During catheterization, left and right ventricular end-diastolic pressures in constrictive pericarditis are approximately ______.

    <p>equal</p> Signup and view all the answers

    Which of the following is a common physical examination finding in constrictive pericarditis?

    <p>Kussmaul's sign</p> Signup and view all the answers

    Which of the following is a cause of constrictive pericarditis?

    <p>Viral infections</p> Signup and view all the answers

    Constrictive pericarditis is characterized by a fibrous and inelastic pericardial sac that enhances heart filling.

    <p>False</p> Signup and view all the answers

    What symptom would most likely be observed in a patient with constrictive pericarditis due to right heart failure?

    <p>Jugular venous distension</p> Signup and view all the answers

    Chronic pericarditis may lead to ______ due to impaired diastolic filling.

    <p>heart failure</p> Signup and view all the answers

    Match the diseases to their corresponding cause of constrictive pericarditis:

    <p>Tuberculosis = Infectious Cause Lymphoma = Neoplastic Cause Rheumatoid Arthritis = Autoimmune Disorder Radiation Therapy = Treatment-related Cause</p> Signup and view all the answers

    Which finding is associated with Kussmaul's sign?

    <p>Inability of jugular venous pressure to decrease upon inspiration</p> Signup and view all the answers

    Hemodynamic changes in constrictive pericarditis may include equal left and right ventricular diastolic pressures.

    <p>True</p> Signup and view all the answers

    Name one symptom indicative of systemic congestion in constrictive pericarditis.

    <p>Pitting edema</p> Signup and view all the answers

    Chronic inflammation of the pericardium may result from ______ therapy.

    <p>radiation</p> Signup and view all the answers

    Which of the following could lead to inferior vena cava back pressure?

    <p>Hepatomegaly</p> Signup and view all the answers

    Study Notes

    Constrictive Pericarditis Overview

    • Chronic pericarditis characterized by a fibrous and inelastic pericardial sac that restricts heart filling.
    • Develops after acute pericarditis due to recurrent episodes or persistent inflammation lasting over three months.

    Causes of Constrictive Pericarditis

    • Infectious:

      • Mycobacterium tuberculosis leads to non-caseating granulomas and extensive fibrosis.
      • Viral infections like Coxsackie B and SARS-CoV-2 may also contribute.

    • Neoplastic:

      • Primary cancers such as lung cancer, lymphoma, leukemia, and renal cell carcinoma can metastasize and cause pericardial involvement.

    • Radiation Therapy:

      • Treatment for chest cancers may cause chronic inflammation of the pericardium due to targeted radiation exposure.

    • Autoimmune Disorders:

      • Conditions like systemic lupus erythematosus (SLE) and rheumatoid arthritis can lead to pericarditis.

    Clinical Features

    • Predominantly presents as right heart failure symptoms due to impaired diastolic filling.
    • Reduced stroke volume and cardiac output lead to heart failure-like symptoms.

    Physical Exam Findings

    • Jugular Venous Distension (JVD):

      • Due to increased venous pressure from insufficient right atrial filling.

    • Hepatomegaly and Ascites:

      • Resulting from inferior vena cava back pressure.

    • Pitting Edema:

      • Fluid accumulation in lower extremities due to systemic congestion.

    Heart Failure Symptoms

    • Symptoms reflect a failure of the right side of the heart more severely than the left.

    • Right Heart Failure Signs:

      • JVD from superior vena cava pressure.
      • Hepatomegaly from inferior vena cava pressure.
      • Ascites due to fluid accumulation in the abdominal cavity.

    • Left Heart Failure Signs:

      • Hypotension due to decreased stroke volume.
      • Pulmonary congestion leading to pulmonary edema.

    Kussmaul's Sign

    • Jugular venous pressure does not decrease upon inspiration, contrary to normal physiology.
    • Reflects impaired filling of the right heart despite lower thoracic pressure during inspiration.

    Auscultation Findings

    • Pericardial Knock:
      • Distinct sound during ventricular diastole, caused by sudden cessation of blood flow into rigid ventricles.
      • Indicates a rush of blood into a ventricle that cannot accommodate due to pericardial constraint.

    Summary

    • Constrictive pericarditis leads to restrictive mechanics of the heart due to fibrous changes of the pericardium, primarily impacting diastolic function.
    • Multiple etiological factors contribute to its development, and the clinical manifestations are dominated by signs of heart failure, particularly on the right side.
    • Unique physical examination findings, including Kussmaul's sign and pericardial knock, assist in diagnosis.### Pulsus Paradoxus
    • Defined as a decrease in systolic blood pressure by ≥10 mmHg during inspiration.
    • Occurs in 20-30% of patients with constrictive pericarditis; also present in other conditions like cardiac tamponade.
    • Normal respiratory patterns affect blood flow across the heart, contributing to subtle blood pressure changes.

    Mechanism of Respiratory Influence

    • During inspiration, right heart inflow increases, slightly shifting the septum, reducing left ventricle volume.
    • During expiration, left heart inflow increases, which expands the left ventricle, leading to normal pressure readings.
    • In constrictive pericarditis, rigid pericardium prevents proper ventricular expansion, causing significant stroke volume decrease during inspiration.

    Diagnostic Findings

    • Electrocardiogram (ECG): May show low QRS voltage due to fibrosis affecting electrical flow.
    • Chest X-Ray: Lateral view preferred to identify pericardial calcifications, especially in tuberculosis.
    • Echocardiogram: Key diagnostic tool showing:
      • Thickened pericardium indicating constriction.
      • Increased blood flow across the tricuspid valve during inspiration (respirophasic flow changes).
      • Septal bounce during inspiration due to pressure shifts.
      • IVC to hepatic vein flow reversal during expiration due to altered hemodynamics.

    Hemodynamic Changes

    • Pressure curves demonstrate a unique dip and plateau pattern, known as the square root sign, during early diastole.
    • Ventricular dependence indicated by equal right and left ventricular diastolic pressures due to constrictive pericarditis.

    Diagnostic Imaging

    • CT/MRI: Effective for showing thickened pericardium, less specific than echocardiography.

    Differentiation: Constrictive Pericarditis vs. Restrictive Cardiomyopathy

    • Constrictive Pericarditis: Issues arise from the pericardium, presenting with:
      • Pericardial knock.
      • Jugular venous distension (JVD) with Kussmaul's sign (static with inspiration).
    • Restrictive Cardiomyopathy: Issues arise from the myocardium, possibly leading to:
      • S3/S4 heart sounds.
      • Mitral/tricuspid regurgitation due to atrial dilation.

    Treatment Overview

    • Treatment specifics were not detailed but focus generally involves managing underlying causes and addressing heart failure symptoms related to fluid overload and pressures.### Constrictive Pericarditis vs. Restrictive Cardiomyopathy
    • Constrictive pericarditis leads to filling restrictions during early diastole, may present with Kussmaul's sign.
    • Differentiating factors include presence of an S3 or S4 heart sound, indicating mitral and tricuspid regurgitation.
    • Pulsus paradoxus is common in constrictive pericarditis but rarely observed in restrictive cardiomyopathy.

    EKG Findings

    • Patients may exhibit low QRS voltages due to pericardial thickness or infiltrations affecting the cardiac conduction system.
    • Conduction blocks may occur in both conditions, indicating compromised electrical conduction.

    Chest X-Ray

    • Generally, no specific findings distinguish constrictive pericarditis or restrictive cardiomyopathy on chest X-ray.

    Echocardiography Findings

    • Marked thickening of the pericardium observed in constrictive pericarditis.
    • Significant respirophasic changes in transvalvular velocities present in constrictive pericarditis, whereas minimal changes noted in restrictive cardiomyopathy.
    • Presence of septal bounce observed in constrictive pericarditis but absent in restrictive cardiomyopathy.

    Hemodynamic Assessment

    • During catheterization, both conditions may show a square root sign.
    • In constrictive pericarditis, left and right ventricular end-diastolic pressures are approximately equal due to pericardial constraint.
    • In restrictive cardiomyopathy, left ventricular end-diastolic pressure is typically more than five mmHg higher than that of the right ventricle, indicating independence.

    Treatment of Constrictive Pericarditis

    • Goals include management of symptoms related to venous congestion (e.g., jugular venous distention, hepatomegaly, ascites, edema).
    • Initial treatment may involve fluid restriction and diuretics (e.g., loop diuretics) to alleviate symptoms.
    • Definitive treatment involves surgical removal of the pericardium (pericardiectomy) to resolve the underlying cause of symptoms.

    Overview of Constrictive Pericarditis

    • A chronic condition causing a fibrous and inelastic pericardial sac, restricting heart filling.
    • Often develops following acute pericarditis due to recurrent inflammation lasting over three months.

    Causes of Constrictive Pericarditis

    • Infectious origins:
      • Mycobacterium tuberculosis can cause non-caseating granulomas and extensive fibrosis.
      • Other viral infections like Coxsackie B and SARS-CoV-2 may play a role.
    • Neoplastic causes:
      • Primary cancers like lung cancer, lymphoma, leukemia, and renal cell carcinoma can metastasize to pericardium.
    • Radiation Therapy:
      • Can lead to chronic inflammation of the pericardium as a consequence of treatment for chest cancers.
    • Autoimmune Disorders:
      • Conditions such as systemic lupus erythematosus (SLE) and rheumatoid arthritis may result in pericarditis.

    Clinical Features

    • Symptoms predominantly reflect right heart failure due to impaired diastolic filling.
    • Reduced stroke volume and cardiac output contribute to heart failure-like manifestations.

    Physical Exam Findings

    • Jugular Venous Distension (JVD):
      • Indicates elevated venous pressure from inadequate right atrial filling.
    • Hepatomegaly and Ascites:
      • Caused by inferior vena cava back pressure.
    • Pitting Edema:
      • Fluid buildup in lower extremities due to systemic congestion.

    Heart Failure Symptoms

    • Right heart failure symptoms tend to be more pronounced than left heart failure.
    • Right heart failure signs include:
      • JVD from superior vena cava pressure.
      • Hepatomegaly from inferior vena cava pressure.
      • Ascites from fluid accumulation in the abdomen.
    • Left heart failure signs include:
      • Hypotension from decreased stroke volume.
      • Pulmonary congestion leading to pulmonary edema.

    Kussmaul's Sign

    • Characterized by non-decrease in jugular venous pressure during inspiration, contrasting with normal physiology.

    Auscultation Findings

    • Pericardial Knock:
      • A distinct sound during ventricular diastole indicating rapid blood flow into a non-compliant ventricle.

    Pulsus Paradoxus

    • Defined by a decrease in systolic blood pressure by ≥10 mmHg during inspiration, found in 20-30% of patients.
    • Also observed in conditions like cardiac tamponade due to respiratory influence on blood flow across the heart.

    Diagnostic Findings

    • Electrocardiogram (ECG):
      • May exhibit low QRS voltage attributed to fibrosis.
    • Chest X-Ray:
      • A lateral view can reveal pericardial calcifications, notably in tuberculosis.
    • Echocardiogram:
      • Thickened pericardium indicating constriction.
      • Respirophasic flow changes across the tricuspid valve.
      • Septal bounce observed during inspiration.

    Hemodynamic Changes

    • Unique pressure curves during diastole show a dip and plateau pattern, referred to as the square root sign.
    • Equal right and left ventricular diastolic pressures indicate ventricular dependence.

    Diagnostic Imaging

    • CT/MRI:
      • Useful in identifying thickened pericardium but less specific than echocardiography.

    Constrictive Pericarditis vs. Restrictive Cardiomyopathy

    • Constrictive Pericarditis:
      • Associated with pericardial knock, JVD, and Kussmaul’s sign.
    • Restrictive Cardiomyopathy:
      • Presents S3/S4 heart sounds and possible atrial dilation leading to regurgitation.

    Treatment Overview

    • General treatment involves managing underlying causes and addressing symptoms of heart failure related to fluid overload.

    EKG Findings

    • Low QRS voltages may indicate pericardial thickness affecting cardiac conduction.
    • Conduction blocks can occur in both conditions, compromising electrical conduction.

    Echocardiography Findings

    • Observes significant thickening of the pericardium in constrictive pericarditis.
    • Marked respirophasic changes in transvalvular velocities are noted, unlike minimal changes in restrictive cardiomyopathy.

    Hemodynamic Assessment

    • Both conditions can present a square root sign on catheterization.
    • In constrictive pericarditis, left and right ventricular end-diastolic pressures are roughly equal.
    • In restrictive cardiomyopathy, left ventricular end-diastolic pressure is usually more than five mmHg higher than that of the right ventricle.

    Treatment of Constrictive Pericarditis

    • Symptomatic management of venous congestion includes fluid restriction and diuretics, such as loop diuretics.
    • Surgical intervention through pericardiectomy may be necessary for definitive treatment.

    Overview of Constrictive Pericarditis

    • A chronic condition causing a fibrous and inelastic pericardial sac, restricting heart filling.
    • Often develops following acute pericarditis due to recurrent inflammation lasting over three months.

    Causes of Constrictive Pericarditis

    • Infectious origins:
      • Mycobacterium tuberculosis can cause non-caseating granulomas and extensive fibrosis.
      • Other viral infections like Coxsackie B and SARS-CoV-2 may play a role.
    • Neoplastic causes:
      • Primary cancers like lung cancer, lymphoma, leukemia, and renal cell carcinoma can metastasize to pericardium.
    • Radiation Therapy:
      • Can lead to chronic inflammation of the pericardium as a consequence of treatment for chest cancers.
    • Autoimmune Disorders:
      • Conditions such as systemic lupus erythematosus (SLE) and rheumatoid arthritis may result in pericarditis.

    Clinical Features

    • Symptoms predominantly reflect right heart failure due to impaired diastolic filling.
    • Reduced stroke volume and cardiac output contribute to heart failure-like manifestations.

    Physical Exam Findings

    • Jugular Venous Distension (JVD):
      • Indicates elevated venous pressure from inadequate right atrial filling.
    • Hepatomegaly and Ascites:
      • Caused by inferior vena cava back pressure.
    • Pitting Edema:
      • Fluid buildup in lower extremities due to systemic congestion.

    Heart Failure Symptoms

    • Right heart failure symptoms tend to be more pronounced than left heart failure.
    • Right heart failure signs include:
      • JVD from superior vena cava pressure.
      • Hepatomegaly from inferior vena cava pressure.
      • Ascites from fluid accumulation in the abdomen.
    • Left heart failure signs include:
      • Hypotension from decreased stroke volume.
      • Pulmonary congestion leading to pulmonary edema.

    Kussmaul's Sign

    • Characterized by non-decrease in jugular venous pressure during inspiration, contrasting with normal physiology.

    Auscultation Findings

    • Pericardial Knock:
      • A distinct sound during ventricular diastole indicating rapid blood flow into a non-compliant ventricle.

    Pulsus Paradoxus

    • Defined by a decrease in systolic blood pressure by ≥10 mmHg during inspiration, found in 20-30% of patients.
    • Also observed in conditions like cardiac tamponade due to respiratory influence on blood flow across the heart.

    Diagnostic Findings

    • Electrocardiogram (ECG):
      • May exhibit low QRS voltage attributed to fibrosis.
    • Chest X-Ray:
      • A lateral view can reveal pericardial calcifications, notably in tuberculosis.
    • Echocardiogram:
      • Thickened pericardium indicating constriction.
      • Respirophasic flow changes across the tricuspid valve.
      • Septal bounce observed during inspiration.

    Hemodynamic Changes

    • Unique pressure curves during diastole show a dip and plateau pattern, referred to as the square root sign.
    • Equal right and left ventricular diastolic pressures indicate ventricular dependence.

    Diagnostic Imaging

    • CT/MRI:
      • Useful in identifying thickened pericardium but less specific than echocardiography.

    Constrictive Pericarditis vs. Restrictive Cardiomyopathy

    • Constrictive Pericarditis:
      • Associated with pericardial knock, JVD, and Kussmaul’s sign.
    • Restrictive Cardiomyopathy:
      • Presents S3/S4 heart sounds and possible atrial dilation leading to regurgitation.

    Treatment Overview

    • General treatment involves managing underlying causes and addressing symptoms of heart failure related to fluid overload.

    EKG Findings

    • Low QRS voltages may indicate pericardial thickness affecting cardiac conduction.
    • Conduction blocks can occur in both conditions, compromising electrical conduction.

    Echocardiography Findings

    • Observes significant thickening of the pericardium in constrictive pericarditis.
    • Marked respirophasic changes in transvalvular velocities are noted, unlike minimal changes in restrictive cardiomyopathy.

    Hemodynamic Assessment

    • Both conditions can present a square root sign on catheterization.
    • In constrictive pericarditis, left and right ventricular end-diastolic pressures are roughly equal.
    • In restrictive cardiomyopathy, left ventricular end-diastolic pressure is usually more than five mmHg higher than that of the right ventricle.

    Treatment of Constrictive Pericarditis

    • Symptomatic management of venous congestion includes fluid restriction and diuretics, such as loop diuretics.
    • Surgical intervention through pericardiectomy may be necessary for definitive treatment.

    Overview of Constrictive Pericarditis

    • A chronic condition causing a fibrous and inelastic pericardial sac, restricting heart filling.
    • Often develops following acute pericarditis due to recurrent inflammation lasting over three months.

    Causes of Constrictive Pericarditis

    • Infectious origins:
      • Mycobacterium tuberculosis can cause non-caseating granulomas and extensive fibrosis.
      • Other viral infections like Coxsackie B and SARS-CoV-2 may play a role.
    • Neoplastic causes:
      • Primary cancers like lung cancer, lymphoma, leukemia, and renal cell carcinoma can metastasize to pericardium.
    • Radiation Therapy:
      • Can lead to chronic inflammation of the pericardium as a consequence of treatment for chest cancers.
    • Autoimmune Disorders:
      • Conditions such as systemic lupus erythematosus (SLE) and rheumatoid arthritis may result in pericarditis.

    Clinical Features

    • Symptoms predominantly reflect right heart failure due to impaired diastolic filling.
    • Reduced stroke volume and cardiac output contribute to heart failure-like manifestations.

    Physical Exam Findings

    • Jugular Venous Distension (JVD):
      • Indicates elevated venous pressure from inadequate right atrial filling.
    • Hepatomegaly and Ascites:
      • Caused by inferior vena cava back pressure.
    • Pitting Edema:
      • Fluid buildup in lower extremities due to systemic congestion.

    Heart Failure Symptoms

    • Right heart failure symptoms tend to be more pronounced than left heart failure.
    • Right heart failure signs include:
      • JVD from superior vena cava pressure.
      • Hepatomegaly from inferior vena cava pressure.
      • Ascites from fluid accumulation in the abdomen.
    • Left heart failure signs include:
      • Hypotension from decreased stroke volume.
      • Pulmonary congestion leading to pulmonary edema.

    Kussmaul's Sign

    • Characterized by non-decrease in jugular venous pressure during inspiration, contrasting with normal physiology.

    Auscultation Findings

    • Pericardial Knock:
      • A distinct sound during ventricular diastole indicating rapid blood flow into a non-compliant ventricle.

    Pulsus Paradoxus

    • Defined by a decrease in systolic blood pressure by ≥10 mmHg during inspiration, found in 20-30% of patients.
    • Also observed in conditions like cardiac tamponade due to respiratory influence on blood flow across the heart.

    Diagnostic Findings

    • Electrocardiogram (ECG):
      • May exhibit low QRS voltage attributed to fibrosis.
    • Chest X-Ray:
      • A lateral view can reveal pericardial calcifications, notably in tuberculosis.
    • Echocardiogram:
      • Thickened pericardium indicating constriction.
      • Respirophasic flow changes across the tricuspid valve.
      • Septal bounce observed during inspiration.

    Hemodynamic Changes

    • Unique pressure curves during diastole show a dip and plateau pattern, referred to as the square root sign.
    • Equal right and left ventricular diastolic pressures indicate ventricular dependence.

    Diagnostic Imaging

    • CT/MRI:
      • Useful in identifying thickened pericardium but less specific than echocardiography.

    Constrictive Pericarditis vs. Restrictive Cardiomyopathy

    • Constrictive Pericarditis:
      • Associated with pericardial knock, JVD, and Kussmaul’s sign.
    • Restrictive Cardiomyopathy:
      • Presents S3/S4 heart sounds and possible atrial dilation leading to regurgitation.

    Treatment Overview

    • General treatment involves managing underlying causes and addressing symptoms of heart failure related to fluid overload.

    EKG Findings

    • Low QRS voltages may indicate pericardial thickness affecting cardiac conduction.
    • Conduction blocks can occur in both conditions, compromising electrical conduction.

    Echocardiography Findings

    • Observes significant thickening of the pericardium in constrictive pericarditis.
    • Marked respirophasic changes in transvalvular velocities are noted, unlike minimal changes in restrictive cardiomyopathy.

    Hemodynamic Assessment

    • Both conditions can present a square root sign on catheterization.
    • In constrictive pericarditis, left and right ventricular end-diastolic pressures are roughly equal.
    • In restrictive cardiomyopathy, left ventricular end-diastolic pressure is usually more than five mmHg higher than that of the right ventricle.

    Treatment of Constrictive Pericarditis

    • Symptomatic management of venous congestion includes fluid restriction and diuretics, such as loop diuretics.
    • Surgical intervention through pericardiectomy may be necessary for definitive treatment.

    Overview of Constrictive Pericarditis

    • A chronic condition causing a fibrous and inelastic pericardial sac, restricting heart filling.
    • Often develops following acute pericarditis due to recurrent inflammation lasting over three months.

    Causes of Constrictive Pericarditis

    • Infectious origins:
      • Mycobacterium tuberculosis can cause non-caseating granulomas and extensive fibrosis.
      • Other viral infections like Coxsackie B and SARS-CoV-2 may play a role.
    • Neoplastic causes:
      • Primary cancers like lung cancer, lymphoma, leukemia, and renal cell carcinoma can metastasize to pericardium.
    • Radiation Therapy:
      • Can lead to chronic inflammation of the pericardium as a consequence of treatment for chest cancers.
    • Autoimmune Disorders:
      • Conditions such as systemic lupus erythematosus (SLE) and rheumatoid arthritis may result in pericarditis.

    Clinical Features

    • Symptoms predominantly reflect right heart failure due to impaired diastolic filling.
    • Reduced stroke volume and cardiac output contribute to heart failure-like manifestations.

    Physical Exam Findings

    • Jugular Venous Distension (JVD):
      • Indicates elevated venous pressure from inadequate right atrial filling.
    • Hepatomegaly and Ascites:
      • Caused by inferior vena cava back pressure.
    • Pitting Edema:
      • Fluid buildup in lower extremities due to systemic congestion.

    Heart Failure Symptoms

    • Right heart failure symptoms tend to be more pronounced than left heart failure.
    • Right heart failure signs include:
      • JVD from superior vena cava pressure.
      • Hepatomegaly from inferior vena cava pressure.
      • Ascites from fluid accumulation in the abdomen.
    • Left heart failure signs include:
      • Hypotension from decreased stroke volume.
      • Pulmonary congestion leading to pulmonary edema.

    Kussmaul's Sign

    • Characterized by non-decrease in jugular venous pressure during inspiration, contrasting with normal physiology.

    Auscultation Findings

    • Pericardial Knock:
      • A distinct sound during ventricular diastole indicating rapid blood flow into a non-compliant ventricle.

    Pulsus Paradoxus

    • Defined by a decrease in systolic blood pressure by ≥10 mmHg during inspiration, found in 20-30% of patients.
    • Also observed in conditions like cardiac tamponade due to respiratory influence on blood flow across the heart.

    Diagnostic Findings

    • Electrocardiogram (ECG):
      • May exhibit low QRS voltage attributed to fibrosis.
    • Chest X-Ray:
      • A lateral view can reveal pericardial calcifications, notably in tuberculosis.
    • Echocardiogram:
      • Thickened pericardium indicating constriction.
      • Respirophasic flow changes across the tricuspid valve.
      • Septal bounce observed during inspiration.

    Hemodynamic Changes

    • Unique pressure curves during diastole show a dip and plateau pattern, referred to as the square root sign.
    • Equal right and left ventricular diastolic pressures indicate ventricular dependence.

    Diagnostic Imaging

    • CT/MRI:
      • Useful in identifying thickened pericardium but less specific than echocardiography.

    Constrictive Pericarditis vs. Restrictive Cardiomyopathy

    • Constrictive Pericarditis:
      • Associated with pericardial knock, JVD, and Kussmaul’s sign.
    • Restrictive Cardiomyopathy:
      • Presents S3/S4 heart sounds and possible atrial dilation leading to regurgitation.

    Treatment Overview

    • General treatment involves managing underlying causes and addressing symptoms of heart failure related to fluid overload.

    EKG Findings

    • Low QRS voltages may indicate pericardial thickness affecting cardiac conduction.
    • Conduction blocks can occur in both conditions, compromising electrical conduction.

    Echocardiography Findings

    • Observes significant thickening of the pericardium in constrictive pericarditis.
    • Marked respirophasic changes in transvalvular velocities are noted, unlike minimal changes in restrictive cardiomyopathy.

    Hemodynamic Assessment

    • Both conditions can present a square root sign on catheterization.
    • In constrictive pericarditis, left and right ventricular end-diastolic pressures are roughly equal.
    • In restrictive cardiomyopathy, left ventricular end-diastolic pressure is usually more than five mmHg higher than that of the right ventricle.

    Treatment of Constrictive Pericarditis

    • Symptomatic management of venous congestion includes fluid restriction and diuretics, such as loop diuretics.
    • Surgical intervention through pericardiectomy may be necessary for definitive treatment.

    Overview of Constrictive Pericarditis

    • A chronic condition causing a fibrous and inelastic pericardial sac, restricting heart filling.
    • Often develops following acute pericarditis due to recurrent inflammation lasting over three months.

    Causes of Constrictive Pericarditis

    • Infectious origins:
      • Mycobacterium tuberculosis can cause non-caseating granulomas and extensive fibrosis.
      • Other viral infections like Coxsackie B and SARS-CoV-2 may play a role.
    • Neoplastic causes:
      • Primary cancers like lung cancer, lymphoma, leukemia, and renal cell carcinoma can metastasize to pericardium.
    • Radiation Therapy:
      • Can lead to chronic inflammation of the pericardium as a consequence of treatment for chest cancers.
    • Autoimmune Disorders:
      • Conditions such as systemic lupus erythematosus (SLE) and rheumatoid arthritis may result in pericarditis.

    Clinical Features

    • Symptoms predominantly reflect right heart failure due to impaired diastolic filling.
    • Reduced stroke volume and cardiac output contribute to heart failure-like manifestations.

    Physical Exam Findings

    • Jugular Venous Distension (JVD):
      • Indicates elevated venous pressure from inadequate right atrial filling.
    • Hepatomegaly and Ascites:
      • Caused by inferior vena cava back pressure.
    • Pitting Edema:
      • Fluid buildup in lower extremities due to systemic congestion.

    Heart Failure Symptoms

    • Right heart failure symptoms tend to be more pronounced than left heart failure.
    • Right heart failure signs include:
      • JVD from superior vena cava pressure.
      • Hepatomegaly from inferior vena cava pressure.
      • Ascites from fluid accumulation in the abdomen.
    • Left heart failure signs include:
      • Hypotension from decreased stroke volume.
      • Pulmonary congestion leading to pulmonary edema.

    Kussmaul's Sign

    • Characterized by non-decrease in jugular venous pressure during inspiration, contrasting with normal physiology.

    Auscultation Findings

    • Pericardial Knock:
      • A distinct sound during ventricular diastole indicating rapid blood flow into a non-compliant ventricle.

    Pulsus Paradoxus

    • Defined by a decrease in systolic blood pressure by ≥10 mmHg during inspiration, found in 20-30% of patients.
    • Also observed in conditions like cardiac tamponade due to respiratory influence on blood flow across the heart.

    Diagnostic Findings

    • Electrocardiogram (ECG):
      • May exhibit low QRS voltage attributed to fibrosis.
    • Chest X-Ray:
      • A lateral view can reveal pericardial calcifications, notably in tuberculosis.
    • Echocardiogram:
      • Thickened pericardium indicating constriction.
      • Respirophasic flow changes across the tricuspid valve.
      • Septal bounce observed during inspiration.

    Hemodynamic Changes

    • Unique pressure curves during diastole show a dip and plateau pattern, referred to as the square root sign.
    • Equal right and left ventricular diastolic pressures indicate ventricular dependence.

    Diagnostic Imaging

    • CT/MRI:
      • Useful in identifying thickened pericardium but less specific than echocardiography.

    Constrictive Pericarditis vs. Restrictive Cardiomyopathy

    • Constrictive Pericarditis:
      • Associated with pericardial knock, JVD, and Kussmaul’s sign.
    • Restrictive Cardiomyopathy:
      • Presents S3/S4 heart sounds and possible atrial dilation leading to regurgitation.

    Treatment Overview

    • General treatment involves managing underlying causes and addressing symptoms of heart failure related to fluid overload.

    EKG Findings

    • Low QRS voltages may indicate pericardial thickness affecting cardiac conduction.
    • Conduction blocks can occur in both conditions, compromising electrical conduction.

    Echocardiography Findings

    • Observes significant thickening of the pericardium in constrictive pericarditis.
    • Marked respirophasic changes in transvalvular velocities are noted, unlike minimal changes in restrictive cardiomyopathy.

    Hemodynamic Assessment

    • Both conditions can present a square root sign on catheterization.
    • In constrictive pericarditis, left and right ventricular end-diastolic pressures are roughly equal.
    • In restrictive cardiomyopathy, left ventricular end-diastolic pressure is usually more than five mmHg higher than that of the right ventricle.

    Treatment of Constrictive Pericarditis

    • Symptomatic management of venous congestion includes fluid restriction and diuretics, such as loop diuretics.
    • Surgical intervention through pericardiectomy may be necessary for definitive treatment.

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    Description

    Explore the key aspects of constrictive pericarditis, a condition characterized by a fibrous pericardial sac that restricts heart filling. This quiz covers its causes, including infections, neoplastic conditions, radiation therapy, and autoimmune disorders, along with clinical features related to right heart failure.

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