Connective Tissue Quiz

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main function of fibroblasts in connective tissue?

  • Facilitating neural communication
  • Storing energy in the form of fat
  • Synthesizing and secreting extracellular components (correct)
  • Transporting white blood cells to sites of infection

Which type of connective tissue cell originates mainly from the bone marrow?

  • Adipose cells
  • Chondrocytes
  • Fibroblasts
  • Mast cells (correct)

What classifies fibroblasts as fixed cells?

  • They differentiate into lymphocytes
  • They circulate freely in the bloodstream
  • They remain in place within the connective tissue (correct)
  • They have a short life span

Which of the following is NOT a function of connective tissue?

<p>Facilitating muscle contraction (D)</p> Signup and view all the answers

Which characteristic is shared by transient cells in connective tissue?

<p>They circulate in the bloodstream before responding to signals (C)</p> Signup and view all the answers

What kind of stem cells give rise to most connective tissue cells?

<p>Mesenchymal stem cells (D)</p> Signup and view all the answers

Which of the following white blood cells is classified as a transient cell?

<p>Neutrophil (B)</p> Signup and view all the answers

What process do lymphocytes undergo as part of their maturation?

<p>Differentiation and receptor expression (A)</p> Signup and view all the answers

What is the key role of macrophages in the immune system?

<p>To phagocytose and destroy unwanted particulate matter (C)</p> Signup and view all the answers

Which of the following statement about lymphocytes is NOT correct?

<p>B cells mature in the thymus (A)</p> Signup and view all the answers

What type of nucleus is characteristic of monocytes?

<p>A large, eccentric, kidney-shaped nucleus (D)</p> Signup and view all the answers

What is the primary function of cytotoxic T lymphocytes?

<p>To directly destroy infected or cancerous cells (C)</p> Signup and view all the answers

What feature distinguishes B lymphocytes from other lymphocyte types?

<p>The production of antibodies in response to antigens (A)</p> Signup and view all the answers

Which component is NOT involved in the process of phagocytosis by macrophages?

<p>Platelets (A)</p> Signup and view all the answers

How are lymphocyte clones formed?

<p>Through the division of immunologically competent cells (D)</p> Signup and view all the answers

Which of the following is TRUE regarding the life spans of lymphocytes?

<p>Some T cells can live for years while some B cells may die in months (C)</p> Signup and view all the answers

What is the primary role of myofibroblasts during the wound healing process?

<p>To produce contractile action to reduce wound size (B)</p> Signup and view all the answers

Which characteristic differentiates unilocular fat cells from multilocular fat cells?

<p>Number of lipid droplets (D)</p> Signup and view all the answers

What happens to myofibroblasts if the injurious stimulus persists?

<p>They result in excessive collagen deposition and fibrosis (A)</p> Signup and view all the answers

Which of the following describes the structure of mast cells?

<p>Ovoid shape with a centrally placed nucleus and abundant secretory granules (D)</p> Signup and view all the answers

Inactive fibroblasts, also known as fibrocytes, can be described as:

<p>Smaller and more ovoid with fewer organelles (C)</p> Signup and view all the answers

What type of tissue is formed by unilocular fat cells?

<p>White adipose tissue (B)</p> Signup and view all the answers

Which chemical mediator is NOT typically contained within mast cell granules?

<p>Collagenase (C)</p> Signup and view all the answers

Which of the following is a key feature of multilocular fat cells?

<p>Have more mitochondria than unilocular fat cells (C)</p> Signup and view all the answers

What characteristic feature is used to identify neutrophils in a blood film?

<p>Multilobed nucleus (B)</p> Signup and view all the answers

Which of the following correctly describes the primary function of eosinophils?

<p>Phagocytose antigen-antibody complexes (D)</p> Signup and view all the answers

Which statement about basophils is true?

<p>They mediate allergic reactions by releasing granule contents. (D)</p> Signup and view all the answers

What happens to neutrophils after performing their function?

<p>They die and form pus cells. (C)</p> Signup and view all the answers

Which condition would likely decrease the number of eosinophils in circulation?

<p>Elevation of blood corticosteroid levels (D)</p> Signup and view all the answers

What unique feature do female neutrophils possess that aids in sex identification?

<p>Drumstick appendage containing Barr body (C)</p> Signup and view all the answers

Which type of granulocyte is primarily involved in the response to parasitic infections?

<p>Eosinophils (D)</p> Signup and view all the answers

Which of the following describes a potential consequence of excessive basophil degranulation?

<p>Circulatory shock due to blood vessel leakiness (A)</p> Signup and view all the answers

What is the primary role of mast cells in the immune system?

<p>They initiate an inflammatory response. (B)</p> Signup and view all the answers

What distinguishes plasma cells from other B lymphocytes?

<p>They manufacture antibodies. (D)</p> Signup and view all the answers

In cases of systemic anaphylaxis, what is the primary risk for hyperallergic individuals?

<p>Severe immediate hypersensitivity reaction. (B)</p> Signup and view all the answers

Which characteristic is NOT true about macrophages?

<p>They primarily function in the bloodstream. (D)</p> Signup and view all the answers

How do leukocytes exit the bloodstream to perform their functions?

<p>Through diapedesis between endothelial cells. (A)</p> Signup and view all the answers

What is a common effect of histamine release during hay fever attacks?

<p>Nasal congestion leading to difficulty in breathing. (A)</p> Signup and view all the answers

Which of the following best describes the cytoplasm of plasma cells?

<p>Intensely basophilic with a pale prenuclear area. (B)</p> Signup and view all the answers

Granulocytes possess which of the following features?

<p>They have specific granules and non-specific granules. (D)</p> Signup and view all the answers

Flashcards

Mesenchymal stem cells

Special cells in the middle layer of the embryo (mesoderm) that have the potential to become many different types of connective tissues.

Fibroblast

A type of connective tissue cell that's responsible for creating the 'glue' and 'fibers' that hold tissues together. They are the most common type of connective tissue cell.

Ground substance

The fluid-filled space between connective tissue cells, containing molecules that help support and communicate with the cells.

Fibers

Strong, rope-like strands found in connective tissue that provide support and structure. They are made up of proteins like collagen and elastin.

Signup and view all the flashcards

Transient cells

A group of cells that are part of the body's immune system and travel through the bloodstream to reach sites of infection or injury.

Signup and view all the flashcards

Fixed cells

Connective tissue cells that are long-lived and permanently reside in a specific connective tissue type.

Signup and view all the flashcards

Mast cells

These cells are key players in fighting infections and allergies. They can release chemicals like histamine, which causes inflammation.

Signup and view all the flashcards

Macrophages

Cells that engulf and destroy invading microorganisms and cellular debris. They are important for clearing up infections and damaged tissue.

Signup and view all the flashcards

Active fibroblast

Active fibroblasts are responsible for producing and secreting collagen and other components of the extracellular matrix.

Signup and view all the flashcards

Inactive fibroblast (Fibrocyte)

Inactive fibroblasts, also known as fibrocytes, are smaller and less active than their active counterparts. They have a more ovoid shape and fewer organelles.

Signup and view all the flashcards

Myofibroblast

Myofibroblasts are specialized fibroblasts that have characteristics of both fibroblasts and smooth muscle cells. They contract to help close wounds and play a role in fibrosis.

Signup and view all the flashcards

Unilocular fat cell

Unilocular fat cells are large cells with a single, large lipid droplet. They make up white adipose tissue.

Signup and view all the flashcards

Multilocular fat cell

Multilocular fat cells are smaller and more polygonal than white fat cells. They contain multiple, small lipid droplets and form brown adipose tissue.

Signup and view all the flashcards

Heparin

Heparin is an anticoagulant released by mast cells, preventing blood clotting.

Signup and view all the flashcards

Histamine & Leukotrienes

Histamine and Leukotrienes are vasodilators and smooth muscle contractors released by mast cells.

Signup and view all the flashcards

Anaphylaxis

A severe, potentially life-threatening allergic reaction triggered by exposure to an allergen, usually after a second exposure. Symptoms include difficulty breathing, hives, and a drop in blood pressure.

Signup and view all the flashcards

Histamine

A chemical released by mast cells and other cells involved in inflammation.

Signup and view all the flashcards

Diapedesis

The process by which white blood cells leave the bloodstream and enter the tissues to fight infection or injury.

Signup and view all the flashcards

Basophilic

The intense blue staining of a cell's cytoplasm, usually due to the presence of a large amount of ribosomes.

Signup and view all the flashcards

Plasma cells

Cells derived from B lymphocytes that produce antibodies, proteins that help the immune system target specific invaders.

Signup and view all the flashcards

Degranulation

The release of granules from a cell, often containing chemicals like histamine, which contributes to inflammation.

Signup and view all the flashcards

Anaphylactic shock

A life-threatening condition that occurs when the body's immune system overreacts to an allergen, causing a rapid and severe drop in blood pressure, airway constriction, and swelling.

Signup and view all the flashcards

Monocyte

The largest white blood cell in the blood, characterized by a kidney-shaped nucleus and abundant lysosomes.

Signup and view all the flashcards

Lymphocyte

A type of white blood cell that is responsible for adaptive immunity, recognizing and attacking specific foreign invaders.

Signup and view all the flashcards

B lymphocyte (B cell)

A type of lymphocyte that matures in the bone marrow and produces antibodies to fight infections.

Signup and view all the flashcards

T lymphocyte (T cell)

A type of lymphocyte that matures in the thymus and directly attacks infected or cancerous cells.

Signup and view all the flashcards

Null cells

A group of lymphocytes that include natural killer (NK) cells and other cells that play a role in innate immunity.

Signup and view all the flashcards

Clone (of lymphocytes)

A group of identical cells that can recognize and respond to the same specific antigen.

Signup and view all the flashcards

What are neutrophils?

The most numerous white blood cells, accounting for 60-70% of the total leukocyte population. They have a multilobed nucleus connected by chromatin and a pale cytoplasm. In females, their nucleus contains a distinctive 'drumstick' appendage containing the inactive second X chromosome (Barr body).

Signup and view all the flashcards

What are eosinophils?

They are characterized by a bilobed nucleus and eosinophilic granules in their cytoplasm. They phagocytose antigen-antibody complexes and kill parasitic invaders.

Signup and view all the flashcards

What are basophils?

They are characterized by an S-shaped nucleus and abundant basophilic granules in their cytoplasm. They mediate allergic and inflammatory reactions by releasing granules containing histamine and heparin.

Signup and view all the flashcards

What are monocytes?

A type of white blood cell with a single large nucleus and abundant cytoplasm. They engulf and destroy bacteria, viruses, and cellular debris.

Signup and view all the flashcards

What are lymphocytes?

A type of agranulocyte responsible for the adaptive immune response. They exist in various forms, including T lymphocytes and B lymphocytes, each with specific roles in recognizing and destroying specific pathogens.

Signup and view all the flashcards

What is neutrophilia?

An increase in the number of neutrophils in the blood. It often indicates a bacterial infection.

Signup and view all the flashcards

How do neutrophils fight bacterial infections?

The process by which neutrophils engulf and destroy bacteria by utilizing the contents of their granules.

Signup and view all the flashcards

What is pus?

The fluid that accumulates at the site of inflammation, often containing dead white blood cells (particularly neutrophils) and bacteria.

Signup and view all the flashcards

Study Notes

Connective Tissue Cells & Immune Cells

  • Connective tissue (CT) forms a continuum with epithelial, muscle, and nervous tissue, maintaining a functional body.
  • CT originates from the mesoderm, containing mesenchymal stem cells.
  • Composed of cells and extracellular matrix (ground substance and fibers).
  • Functions vary, but generally include structural support, exchange medium, defense, and fat storage.

Fixed Cells

  • Stable, long-lived cells residing in the connective tissue.
  • Examples: fibroblasts and adipocytes (fat cells).

Fibroblasts

  • Most abundant fixed cell.
  • Synthesize and secrete extracellular components (fibers and ground substance).
  • Active fibroblasts are involved in protein synthesis, especially during wound healing.
  • Inactive forms (fibrocytes) are smaller, more ovoid, and have fewer organelles.
  • Myofibroblasts are transitional forms, resembling smooth muscle, involved in wound healing.

Adipocytes

  • Fully differentiated cells that do not divide.
  • Store triglycerides (fat).
  • Two types: unilocular (single large lipid droplet, white adipose tissue) and multilocular (multiple small lipid droplets, brown adipose tissue).
  • Unilocular adipocytes have a signet ring appearance under a microscope (cytoplasm and nucleus are pushed to the edge by large fat droplet).

Mast Cells

  • Ovoid cells with a centrally placed nucleus.
  • Contain granules with chemical mediators (e.g., heparin, histamine, leukotrienes, interleukins, TNF-α).
  • Initiate inflammatory responses, including immediate hypersensitivity (e.g., hay fever, anaphylaxis).

Macrophages

  • Derived from circulating monocytes.
  • Phagocytic cells, removing cellular debris and foreign invaders.
  • Crucial in the inflammatory and immune response.
  • Present antigens to T cells (antigen-presenting cells).

Plasma Cells

  • Derived from B lymphocytes.
  • Produce antibodies (immunoglobulins).

Lymphocytes

  • Rounded cells with a prominent nucleus.
  • Three types: B cells, T cells, and null cells.
  • Crucial for adaptive immunity.
  • Differentiate into memory cells (long-lived) or effector cells (short-lived, active in response to specific antigens).

White Blood Cells (Leukocytes)

  • Originate in bone marrow.
  • Circulate in the blood then migrate to connective tissue.
  • Classified into granulocytes (with specific and non-specific granules) and non-granulocytes (without specific granules).
    • Examples: neutrophils, eosinophils, basophils, lymphocytes, and monocytes.

Neutrophils

  • Most abundant white blood cells.
  • First responders to bacterial infections.
  • Phagocytic, engulfing and destroying bacteria.

Eosinophils

  • Involved in allergic reactions and parasitic infections.
  • Phagocytic, killing parasites, and modulating allergic inflammation.

Basophils

  • Involved in allergic and inflammatory reactions.
  • Release histamine and heparin (anticoagulant).

Monocytes

  • Largest white blood cells.
  • Mature into macrophages in connective tissue.

Clinical Significance

  • Different cell types, numbers, and activation states are indicators of health status and disease.
  • Variations in cell function play roles in various conditions including allergies, infections, and inflammation.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Connective Tissue Cells: Fibroblasts Overview
6 questions
Connective Tissue Overview
21 questions
Connective Tissue Functions and Components
48 questions
Use Quizgecko on...
Browser
Browser