Questions and Answers
What is the brand name of colchicine?
What is the pharmacologic classification of colchicine?
What is the action of colchicine in treating gout?
It involves a reduction in lactic acid production by leukocytes, decreasing uric acid deposition and phagocytosis, inhibiting inflammation and reducing pain and swelling.
Colchicine can be administered via multiple routes.
Signup and view all the answers
What are the indications for using colchicine?
Signup and view all the answers
Which of the following are known side effects of colchicine?
Signup and view all the answers
What should be monitored as part of nursing considerations for colchicine?
Signup and view all the answers
Grapefruit juice may decrease the adverse reactions when taking colchicine.
Signup and view all the answers
What dietary considerations should patients taking colchicine follow?
Signup and view all the answers
Study Notes
Colchicine Overview
- Brand name: Colcyrus
- Therapeutic classification: antigout
- Pharmacologic classification: colchicum autumnale alkaloid
Mechanism of Action
- Anti-inflammatory effects in gout: reduces lactic acid production by leukocytes, decreasing uric acid deposition.
- Inhibits phagocytosis, leading to lower inflammation, pain, and swelling.
- Prevents neutrophils from reaching the inflammation site.
Administration
- Route of administration: only available as oral (PO).
Indications
- Used for recurring gouty arthritis and acute gout episodes.
- Effective in treating Mediterranean fever.
Side Effects
- Common side effects include nausea, vomiting, abdominal pain, and mental confusion.
- Potential for neutropenia and bone marrow depression.
Nursing Considerations
- Monitor lab tests: serum uric acid, creatinine, CBC, platelet count, serum electrolytes, and urinalysis at baseline and periodically.
- Advise taking medication on an empty stomach.
- Grape juice can exacerbate adverse reactions; caution is warranted.
- Encourage high fluid intake, and advise avoiding purine-rich foods and alcohol.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge on colchicine with these flashcards. Learn about its brand name, classification, and pharmacological actions. This quiz is perfect for students and professionals in pharmacy or medicine.
