Podcast
Questions and Answers
What is the usual loading dose of Clopidogrel?
What is the usual loading dose of Clopidogrel?
- 150 mg
- 300 mg (correct)
- 600 mg
- 75 mg
When is the maximum inhibition of platelet aggregation achieved with repeated doses of 75 mg/d Clopidogrel?
When is the maximum inhibition of platelet aggregation achieved with repeated doses of 75 mg/d Clopidogrel?
- Within 1-2 days
- Within 10 days
- Within 3-7 days (correct)
- Within 24 hours
What is the duration of platelet inhibition with Clopidogrel?
What is the duration of platelet inhibition with Clopidogrel?
- 24 hours
- 7-10 days (correct)
- 14-21 days
- 3-5 days
In which patient population is dual antiplatelet therapy with Clopidogrel and aspirin commonly used?
In which patient population is dual antiplatelet therapy with Clopidogrel and aspirin commonly used?
What role does Clopidogrel play in patients with atrial fibrillation who cannot take vitamin K antagonists?
What role does Clopidogrel play in patients with atrial fibrillation who cannot take vitamin K antagonists?
What do prescribers use Clopidogrel as an alternative antiplatelet drug for?
What do prescribers use Clopidogrel as an alternative antiplatelet drug for?
Which adverse effect is commonly associated with clopidogrel use?
Which adverse effect is commonly associated with clopidogrel use?
What is a contraindication to the use of clopidogrel?
What is a contraindication to the use of clopidogrel?
Which population group is more likely to experience bleeding and complications with antiplatelet drugs like clopidogrel?
Which population group is more likely to experience bleeding and complications with antiplatelet drugs like clopidogrel?
What is a potential consequence of clopidogrel accumulation in individuals with hepatic impairment?
What is a potential consequence of clopidogrel accumulation in individuals with hepatic impairment?
What is recommended for CYP2C19 poor or intermediate metabolizers due to variant forms of the enzyme?
What is recommended for CYP2C19 poor or intermediate metabolizers due to variant forms of the enzyme?
Why is caution needed when using clopidogrel in pregnant women?
Why is caution needed when using clopidogrel in pregnant women?
What is the primary enzyme responsible for converting Clopidogrel to its active form?
What is the primary enzyme responsible for converting Clopidogrel to its active form?
Which of the following are considered shortcomings of Clopidogrel?
Which of the following are considered shortcomings of Clopidogrel?
What is the mechanism of action of Clopidogrel?
What is the mechanism of action of Clopidogrel?
When does platelet inhibition typically occur after a single dose of Clopidogrel?
When does platelet inhibition typically occur after a single dose of Clopidogrel?
In what way is Clopidogrel similar to aspirin in terms of its effect on platelets?
In what way is Clopidogrel similar to aspirin in terms of its effect on platelets?
Which enzyme is responsible for the metabolism of Clopidogrel to its active form to a lesser extent?
Which enzyme is responsible for the metabolism of Clopidogrel to its active form to a lesser extent?
