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ADP Receptor Antagonists in Dual Antiplatelet Therapy

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17 Questions

Which anticoagulant acts more on factor X, is given subcutaneously, and has a longer duration of action?

LMWH

What is the characteristic of LMWH that makes it less likely to induce immune reactions compared to heparin?

Subcutaneous administration

Which group of anticoagulants are specifically recommended in the treatment of thrombosis, especially due to immune heparin reactions?

Direct Thrombin Inhibitors

How do Factor X Inhibitors suppress thrombin formation?

By binding to antithrombin III indirectly

In which form are the Factor X Inhibitors typically administered during interventions?

Parenteral forms

What is a common feature of NOACs?

Include both Oral Direct Thrombin Inhibitors and Factor X Inhibitors

What is the mechanism of action of Factor X inhibitors?

Inhibiting coagulation factors (II, X, IX, XI, XII)

Which type of anticoagulant is Unfractionated Heparin (UFH)?

Direct thrombin inhibitor

What is the key characteristic of Direct Thrombin Inhibitors?

They directly inhibit thrombin activity

Which anticoagulant has the advantage of being rapid and short-acting?

Unfractionated Heparin (UFH)

What distinguishes Low Molecular Weight Heparin (LMWH) from Unfractionated Heparin (UFH)?

LMWH has a longer duration of action

Which category of anticoagulants includes drugs variably binding and activating antithrombin III?

Indirect Thrombin Inhibitors

Which of the following is a key mechanism of action of warfarin?

Inhibits the activation of coagulation factors II, VII, IX, and X

What is the key advantage of the newly introduced oral anticoagulants (NOACs) compared to warfarin?

NOACs have fewer side effects and drug interactions

Which of the following is a key characteristic of low-molecular-weight heparins (LMWHs)?

LMWHs have a longer half-life than unfractionated heparin

What is the primary purpose of thrombolytics?

To dissolve already formed thrombi

Which of the following anticoagulants is not recommended for use during pregnancy?

Warfarin

Learn about ADP receptor antagonists, such as clopidogrel, which are used in Dual Antiplatelet Therapy (DAPT) to prevent platelet activation. Understand the loading doses and the importance of combining ADP antagonists with aspirin for certain medical conditions.

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