Podcast
Questions and Answers
What is the mechanism of action of platelet aggregation inhibitors like Clopidogrel and Ticlopidine?
What is the mechanism of action of platelet aggregation inhibitors like Clopidogrel and Ticlopidine?
- Increasing cAMP levels
- Blocking binding sites on GPIIb/IIIa receptors (correct)
- Binding to thrombin
- Enhancing fibrinogen production
Which platelet aggregation inhibitor is a monoclonal antibody?
Which platelet aggregation inhibitor is a monoclonal antibody?
- Dipyridamole
- Abciximab (correct)
- Clopidogrel
- Eptifibatide
What is the mechanism of action of Dipyridamole?
What is the mechanism of action of Dipyridamole?
- Reducing cAMP levels
- Inhibiting vitamin K synthesis
- Blocking fibrinogen binding only
- Increasing adenosine levels and blocking fibrinogen binding (correct)
Which platelet aggregation inhibitor is indicated for reducing symptoms of intermittent claudication?
Which platelet aggregation inhibitor is indicated for reducing symptoms of intermittent claudication?
What do anticoagulants like Heparin and LMWH primarily target in the coagulation cascade?
What do anticoagulants like Heparin and LMWH primarily target in the coagulation cascade?
Why are LMWHs considered favorable for pregnant women?
Why are LMWHs considered favorable for pregnant women?
Which anticoagulant is initially used as rat poison?
Which anticoagulant is initially used as rat poison?
What is the mechanism of action of thrombolytic agents like Alteplase and Streptokinase?
What is the mechanism of action of thrombolytic agents like Alteplase and Streptokinase?
What is the primary adverse effect of thrombolytic agents like Streptokinase?
What is the primary adverse effect of thrombolytic agents like Streptokinase?
Which factor is responsible for the formation of a hemostatic plug by stabilizing inactive GP IIb/ IIIa receptors?
Which factor is responsible for the formation of a hemostatic plug by stabilizing inactive GP IIb/ IIIa receptors?
What effect does acetylsalicylic acid (ASA) have on COX-1?
What effect does acetylsalicylic acid (ASA) have on COX-1?
What is the main role of thrombolytic drugs in the context of clot formation?
What is the main role of thrombolytic drugs in the context of clot formation?
Which drug inhibits the binding of Adenosine diphosphate (ADP), thereby preventing the activation of GIIb/IIIa receptors?
Which drug inhibits the binding of Adenosine diphosphate (ADP), thereby preventing the activation of GIIb/IIIa receptors?
What is the primary function of Factor XIII in the coagulation cascade?
What is the primary function of Factor XIII in the coagulation cascade?
Which agent acts by irreversibly acetylating a serine on COX-1, leading to inhibition of thromboxane A2 synthesis?
Which agent acts by irreversibly acetylating a serine on COX-1, leading to inhibition of thromboxane A2 synthesis?
What effect does prostacyclin have on platelet function?
What effect does prostacyclin have on platelet function?
Which drug is considered a hemorheologic agent?
Which drug is considered a hemorheologic agent?
What is the primary effect of Factor XIII in the coagulation cascade?
What is the primary effect of Factor XIII in the coagulation cascade?
Which condition can be prevented or treated using platelet aggregation inhibitors?
Which condition can be prevented or treated using platelet aggregation inhibitors?
