10 Questions
What is the primary route of excretion for clopidogrel?
Equally in urine and feces
What effect would co-prescribing a CYP2C19 inhibitor with clopidogrel have?
Increased risk of bleeding
What is the mechanism of action of abciximab?
Competitive antagonism of glycoprotein IIb/IIIa receptor complex
What is the mechanism of action of aspirin?
Inhibition of thromboxane A2 production
For which condition is aspirin used in patients undergoing percutaneous coronary intervention (PCI)?
Preventing acute cardiac ischemic complications
In what type of patients is aspirin used to manage unstable angina not responding to conventional therapy?
Patients scheduled for PCI
What is the mechanism of action of direct thrombin inhibitors (DTIs)?
Binding to the active site of both free and fibrin-bound thrombin
In which patient population can bivalirudin be used as an alternative to heparin?
Patients with heparin-induced thrombocytopenia
What is a common adverse effect associated with dabigatran use?
Gastrointestinal adverse effects
Why are elderly patients more sensitive to the anticoagulation effects of certain medications?
Due to decreased metabolism and elimination of the medication in the elderly population
Test your knowledge of clopidogrel's pharmacokinetics and pharmacogenomics with this quiz. Explore its metabolism, administration, excretion, and potential adverse effects. Delve into the implications of co-prescribing CYP2C19 inhibitors or inducers with clopidogrel.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
