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Questions and Answers
What is the primary route of excretion for clopidogrel?
What is the primary route of excretion for clopidogrel?
- Feces only
- Exhaled air
- Equally in urine and feces (correct)
- Urine only
What effect would co-prescribing a CYP2C19 inhibitor with clopidogrel have?
What effect would co-prescribing a CYP2C19 inhibitor with clopidogrel have?
- Decreased risk of bleeding
- No effect on adverse effects
- Reduced risk of thrombotic thrombocytopenic purpura
- Increased risk of bleeding (correct)
What is the mechanism of action of abciximab?
What is the mechanism of action of abciximab?
- Competitive antagonism of glycoprotein IIb/IIIa receptor complex (correct)
- Prevention of platelet aggregation via binding to thromboxane A2 receptor
- Inhibition of thrombin activity
- Inhibition of P450 CYP2C19 enzyme
What is the mechanism of action of aspirin?
What is the mechanism of action of aspirin?
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For which condition is aspirin used in patients undergoing percutaneous coronary intervention (PCI)?
For which condition is aspirin used in patients undergoing percutaneous coronary intervention (PCI)?
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In what type of patients is aspirin used to manage unstable angina not responding to conventional therapy?
In what type of patients is aspirin used to manage unstable angina not responding to conventional therapy?
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What is the mechanism of action of direct thrombin inhibitors (DTIs)?
What is the mechanism of action of direct thrombin inhibitors (DTIs)?
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In which patient population can bivalirudin be used as an alternative to heparin?
In which patient population can bivalirudin be used as an alternative to heparin?
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What is a common adverse effect associated with dabigatran use?
What is a common adverse effect associated with dabigatran use?
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Why are elderly patients more sensitive to the anticoagulation effects of certain medications?
Why are elderly patients more sensitive to the anticoagulation effects of certain medications?
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