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Questions and Answers
What adverse reaction was frequently produced by benoxaprofen?
What adverse reaction was frequently produced by benoxaprofen?
- Renal impairment
- Hepatic failure
- Photosensitivity reactions (correct)
- Reduced excretion
What was the first drug studied by PEM in England?
What was the first drug studied by PEM in England?
- NSAID
- HRT
- Benoxaprofen (correct)
- COCs
What led to the withdrawal of benoxaprofen in 1982?
What led to the withdrawal of benoxaprofen in 1982?
- PEM study revealing serious ADRs
- Reduced excretion in elderly patients
- Five deaths related to hepatic and renal failure (correct)
- Primitive computer systems
Why were many of the patients who experienced serious ADRs with benoxaprofen elderly?
Why were many of the patients who experienced serious ADRs with benoxaprofen elderly?
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What pointed to the need for purpose-designed databases in relation to benoxaprofen?
What pointed to the need for purpose-designed databases in relation to benoxaprofen?
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