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Questions and Answers
What is the mechanism for the adverse drug reaction (ADR) causing prolongation of the QT interval on the electrocardiogram?
What is the mechanism for the adverse drug reaction (ADR) causing prolongation of the QT interval on the electrocardiogram?
- Exaggerated therapeutic response at target site
- Desired pharmacological effect at another site
- Triggering an immunological response
- Additional (secondary) pharmacological actions (correct)
Which of the following is an example of a unique syndrome caused only by a specific drug?
Which of the following is an example of a unique syndrome caused only by a specific drug?
- Headache with glyceryltrinitrate
- Prolongation of the QT interval on the electrocardiogram
- Bleeding with warfarin
- Vaginal cancer in young women caused by maternal exposure to diethylstilboestrol (correct)
Which adverse effect is mentioned to be caused by practolol?
Which adverse effect is mentioned to be caused by practolol?
- Eosinophilia‐myalgia syndrome
- Vaginal cancer in young women
- Oculomucocutaneous syndrome (correct)
- Fibrosing colonopathy
What is the adverse effect caused by some l‐tryptophan products?
What is the adverse effect caused by some l‐tryptophan products?
Which of the following represents triggering an immunological response as a mechanism for adverse drug reactions?
Which of the following represents triggering an immunological response as a mechanism for adverse drug reactions?
What is the main advantage of selective serotonin re‐uptake inhibitors (SSRIs) over older tricyclic antidepressants?
What is the main advantage of selective serotonin re‐uptake inhibitors (SSRIs) over older tricyclic antidepressants?
What controversial issues have been associated with the use of SSRIs?
What controversial issues have been associated with the use of SSRIs?
Which specific SSRI was identified to have a higher incidence of withdrawal reactions?
Which specific SSRI was identified to have a higher incidence of withdrawal reactions?
What is the potential risk associated with depressed patients taking an overdose of older tricyclic antidepressants?
What is the potential risk associated with depressed patients taking an overdose of older tricyclic antidepressants?
What contributed to the widespread use of selective serotonin re‐uptake inhibitors (SSRIs) over older tricyclic antidepressants?
What contributed to the widespread use of selective serotonin re‐uptake inhibitors (SSRIs) over older tricyclic antidepressants?
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