Clinical Laboratory: Pathology Overview
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Questions and Answers

Which component of blood is absent in serum but present in plasma?

  • Fibrinogen (correct)
  • White Blood Cells
  • Platelets
  • Red Blood Cells
  • What is the primary responsibility of the Cytogenetics division within the Department of Pathology?

  • Analysing body fluids for cancer cells
  • Performing genetic testing on various specimens (correct)
  • Examining tissues under a microscope
  • Conducting hormone level tests
  • What is the role of the lavender collection tube in hematology sample collection?

  • To separate plasma from red blood cells
  • To prevent clotting due to the presence of an anticoagulant (correct)
  • To promote rapid clotting of blood
  • To enhance the visibility of white blood cells
  • Which of the following best describes a Complete Blood Count (CBC)?

    <p>A combined assessment of different cellular elements in blood</p> Signup and view all the answers

    What does the White Blood Cell differential entail in hematology?

    <p>Identifying specific types of white blood cells and their functions</p> Signup and view all the answers

    Who developed the first almost completely internal pacemaker?

    <p>Wilson Greatbatch</p> Signup and view all the answers

    What significant medical device was invented first by Paul Zoll?

    <p>External cardiac pacemaker</p> Signup and view all the answers

    Which invention significantly advanced the field of cardiology and was performed by Werner Foesmann in 1928?

    <p>Cardiac catheterization</p> Signup and view all the answers

    Which medical imaging technology was jointly developed by Godfrey Hounsfield and Allen Cormack?

    <p>Computed tomography (CT) scanner</p> Signup and view all the answers

    Which significant healthcare invention was introduced by the United States government in 1976?

    <p>First regulatory system for medical devices</p> Signup and view all the answers

    Study Notes

    Laboratory Organizational Divisions

    • Department of Pathology divided into Anatomical and Clinical categories.
    • Anatomical division includes Cytology, Histology, and Cytogenetics for tissue analysis.
    • Cytology focuses on detecting abnormal cells, including cancer.
    • Histology analyzes surgical specimens, biopsies, frozen sections, and autopsies.
    • Cytogenetics conducts genetic testing through blood, amniotic fluid, tissue, and bone marrow.

    Clinical Division

    • Clinical division encompasses several areas: Hematology, Coagulation, Chemistry, Blood Bank, Serology, Microbiology, Urinalysis, and Phlebotomy.
    • Laboratory Information System (LIS) is essential for specimen processing.

    Hematology Insights

    • Analyzes the formed elements of blood, typically using whole blood obtained with anticoagulant.
    • Whole blood analysis includes plasma (liquid not allowed to clot) and serum (liquid allowed to clot).
    • Complete Blood Count (CBC) is the most common test for assessing blood components.
    • White Blood Cell (WBC) counts and types are important for diagnosing infections and other conditions.

    Historical Medical Innovations

    • 1956: Patenting of plastic disposable syringes connects to 1.3 million annual deaths from unsafe injections.
    • 1895: Wilhelm Roentgen discovered X-rays, revolutionizing medical imaging.
    • 1928: First cardiac catheterization demonstrated feasibility of delivering drugs directly to the heart.
    • 1970: Development of the first computerized axial tomography (CT) scanner and major advancements in imaging technology, such as MRI and PET scans.

    Future Innovations in Healthcare

    • Need for long-lasting, fast-charging batteries in medical devices, with new technology like aluminum-ion batteries promising efficiency.
    • Micro supercapacitors aim to charge rapidly while maintaining energy capacity, supporting more energy-efficient devices.
    • Skin power technology harnesses energy from skin friction, potentially eliminating the need for traditional batteries in wearables.

    Unusual Surgical Procedures

    • Rotationplasty is a radical reconstructive surgery that repurposes the ankle as a knee joint post-leg amputation.
    • Rise of telemedicine as a flexible and accessible healthcare option, particularly benefitting remote patients.

    Importance of Interoperability in Healthcare

    • Essential for seamless data exchange across systems, improving efficiency, and reducing costs.
    • Provides clinicians with timely information to enhance patient care and diagnosis.

    Technology Application in Healthcare

    • AI aids in disease diagnosis and medical imaging by processing significant amounts of data.
    • Healthcare operations benefited from technology improvements are optimizing the use of electronic medical records.
    • Clinical trials are evolving through decentralized methods utilizing smart devices and telehealth.

    Microscope Care and Handling

    • Microscopes require careful cleaning with lens paper and should not be left with oil on lenses.
    • When moving, one hand should support the base while the other holds the arm to avoid damage.
    • Storage practices include positioning the low power objective and covering the microscope to keep it dust-free.

    Microscope Operational Principles

    • Resolution and numerical aperture are key to understanding the quality of microscope lenses.
    • Parfocal quality in microscopes minimizes focus adjustments during objective changes.
    • The refractive index affects the light's pathway as it transitions from the slide to the air, impacting image clarity.

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    Description

    This quiz covers the organizational divisions within a clinical laboratory, focusing on the Department of Pathology. You'll learn about anatomical pathology, cytology, histology, and cytogenetics, including their roles in diagnosing diseases such as cancer and genetic testing.

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