Clinical Immunology - Immune Deficiencies

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What are primary immune deficiencies?

Primary immune deficiencies are caused by intrinsic or congenital defects, usually genetic in nature.

How do secondary immune deficiencies differ from primary immune deficiencies?

Secondary immune deficiencies are caused by environmental factors such as infection, therapeutic treatments, cancer, and malnutrition, while primary immune deficiencies are caused by intrinsic or congenital defects.

At what age do most primary immune deficiencies become apparent?

Most primary immune deficiencies become apparent at about 6 months of age, when the maternally derived antibodies begin to disappear and the infant becomes dependent on his or her own immune system.

How many primary immune deficiency diseases have been identified in humans?

Over 100 primary immune deficiency diseases have been identified in humans.

What are some examples of environmental causes that can lead to secondary immune deficiencies?

Infection, therapeutic treatments, cancer, and malnutrition can all lead to secondary immune deficiencies.

What is the main characteristic of overt failures of the immune system?

Reduced ability to resist infection

How do primary immune deficiencies differ from secondary immune deficiencies?

Primary immune deficiencies are congenital, while secondary immune deficiencies are acquired

At what age do most primary immune deficiencies become apparent?

Around 6 months of age

What causes secondary immune deficiencies?

Malnutrition and cancer

How many primary immune deficiency diseases have been identified in humans?

Over 100

Primary immune deficiencies are caused by environmental factors such as infection, therapeutic treatments, cancer, and malnutrition.

False

Over 100 primary immune deficiency diseases have been identified in humans.

True

Most primary immune deficiencies become apparent at about 6 months of age.

True

Secondary immune deficiencies are caused by intrinsic or congenital defects.

False

Affected individuals with primary immune deficiencies are more susceptible to infection.

True

Test your knowledge on immune deficiencies and their impact on clinical function. Learn about the causes and types of immune deficiencies and their clinical implications.

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