Clinical  Immunology (Lec 3) (Set 1)
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Questions and Answers

Which cells present antigens to T-cells?

  • Dendritic cells (correct)
  • Lymphocytes
  • Neutrophils
  • Macrophages
  • What is the main effector cell of acute inflammation?

  • Macrophages
  • Dendritic cells
  • T-cells
  • Neutrophils (correct)
  • Which cells become macrophages in the tissue?

  • T-cells
  • Monocytes (correct)
  • Macrophages
  • Neutrophils
  • What is the lifespan of a neutrophil?

    <p>A few days</p> Signup and view all the answers

    What is the main cell type involved in chronic inflammation?

    <p>Macrophages</p> Signup and view all the answers

    What is the major complication of Crohn's disease?

    <p>Stricture</p> Signup and view all the answers

    Which of the following is a possible outcome after cell death following tissue damage?

    <p>Restitution</p> Signup and view all the answers

    What is the initial response to tissue damage?

    <p>Acute inflammatory reaction</p> Signup and view all the answers

    What is the difference between acute and chronic inflammation?

    <p>Acute inflammation is a normal process, while chronic inflammation is abnormal.</p> Signup and view all the answers

    What is an acute inflammatory exudate composed of?

    <p>Fluids and proteins</p> Signup and view all the answers

    What is the purpose of an acute inflammatory exudate?

    <p>To destroy and eliminate infective agents</p> Signup and view all the answers

    Which type of immunity involves the generation of antigen-specific antibodies and T-cells?

    <p>Adaptive immunity</p> Signup and view all the answers

    What triggers the innate immune response?

    <p>Pathogen-associated molecular patterns (PAMPs)</p> Signup and view all the answers

    Which type of immunodeficiency is a rare genetic disorder where there is little or no function of white blood cells?

    <p>Severe combined immunodeficiency (SCID)</p> Signup and view all the answers

    Which virus infects and destroys T-lymphocytes, leading to immunodeficiency?

    <p>Human Immunodeficiency virus (HIV)</p> Signup and view all the answers

    What is the normal range for white blood cell (WBC) count in a healthy individual?

    <p>4,000 to 11,000 cells/µL of blood</p> Signup and view all the answers

    Which technique is used to study protein expression on cells and can be performed on tissue sections or in cell suspensions?

    <p>Immunophenotyping</p> Signup and view all the answers

    Which method allows for the assessment of multiple cell types at the same time but results in the loss of tissue structure during processing?

    <p>Flow cytometry</p> Signup and view all the answers

    Which type of immunity is generated via natural exposure or active vaccination and confers lasting immunity?

    <p>Adaptive immunity</p> Signup and view all the answers

    True or false: Neutrophils are the main effector cells of chronic inflammation?

    <p>False</p> Signup and view all the answers

    True or false: Macrophages can form discrete clusters called granulomas in granulomatous inflammation?

    <p>True</p> Signup and view all the answers

    True or false: Chronic inflammation can result in fibrosis and stricture formation in Crohn's disease?

    <p>True</p> Signup and view all the answers

    True or false: Chronic inflammation is a normal, healthy, temporary process designed to eliminate damaging stimuli and heal damage?

    <p>False</p> Signup and view all the answers

    True or false: Chronic inflammation occurs when the damaging stimulus cannot be removed and the inflammatory process persists, becoming damaging to the host tissues?

    <p>True</p> Signup and view all the answers

    True or false: Acute inflammation is characterized by four cardinal effects including redness, heat, pain, and swelling?

    <p>True</p> Signup and view all the answers

    Immunodeficiency can only be inherited and not acquired or result from exposure to damaging stimuli.

    <p>False</p> Signup and view all the answers

    Immunodeficiency can lead to unusual infections and cancer.

    <p>True</p> Signup and view all the answers

    Immunophenotyping is a technique used to study protein expression on cells and can only be performed on tissue sections.

    <p>False</p> Signup and view all the answers

    Flow cytometry is a higher throughput technique compared to microscopy and is less prone to human error.

    <p>True</p> Signup and view all the answers

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