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Questions and Answers
What physical findings are characteristically associated with severe insulin resistance in patients with the metabolic syndrome?
What physical findings are characteristically associated with severe insulin resistance in patients with the metabolic syndrome?
In the INTERHEART study, which component of the metabolic syndrome had a stronger odds ratio (OR) for acute myocardial infarction than others?
In the INTERHEART study, which component of the metabolic syndrome had a stronger odds ratio (OR) for acute myocardial infarction than others?
Which of the following diseases is NOT mentioned as being associated with the metabolic syndrome?
Which of the following diseases is NOT mentioned as being associated with the metabolic syndrome?
How does the relative risk for new-onset cardiovascular disease (CVD) in patients with metabolic syndrome compare to those without the syndrome?
How does the relative risk for new-onset cardiovascular disease (CVD) in patients with metabolic syndrome compare to those without the syndrome?
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How do free fatty acids (FFAs) impact insulin sensitivity in muscle?
How do free fatty acids (FFAs) impact insulin sensitivity in muscle?
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What is a consequence of hyperinsulinemia in the context of the metabolic syndrome?
What is a consequence of hyperinsulinemia in the context of the metabolic syndrome?
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How do interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) contribute to insulin resistance in the metabolic syndrome?
How do interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) contribute to insulin resistance in the metabolic syndrome?
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What is the effect of free fatty acids (FFAs) on the production of very-low-density lipoproteins (VLDLs)?
What is the effect of free fatty acids (FFAs) on the production of very-low-density lipoproteins (VLDLs)?
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Which mechanism contributes to a pro-thrombotic state in individuals with the metabolic syndrome?
Which mechanism contributes to a pro-thrombotic state in individuals with the metabolic syndrome?
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What effect does hyperleptinemia have on individuals with leptin resistance?
What effect does hyperleptinemia have on individuals with leptin resistance?
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What is one of the roles of the gut microbiome in the development of obesity and metabolic disorders?
What is one of the roles of the gut microbiome in the development of obesity and metabolic disorders?
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Which factor is associated with the defect in mitochondrial oxidative phosphorylation in insulin-resistant individuals?
Which factor is associated with the defect in mitochondrial oxidative phosphorylation in insulin-resistant individuals?
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What is one potential consequence of leptin resistance in the brain and other tissues?
What is one potential consequence of leptin resistance in the brain and other tissues?
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How does leptin normally regulate cardiac and vascular function?
How does leptin normally regulate cardiac and vascular function?
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How do free fatty acids (FFAs) impact insulin sensitivity in muscle?
How do free fatty acids (FFAs) impact insulin sensitivity in muscle?
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What is the role of hyperinsulinemia in contributing to hypertension in the context of the metabolic syndrome?
What is the role of hyperinsulinemia in contributing to hypertension in the context of the metabolic syndrome?
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How do interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) affect insulin resistance in the metabolic syndrome?
How do interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) affect insulin resistance in the metabolic syndrome?
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What do high levels of circulating glucose and free fatty acids (FFAs) do to pancreatic insulin secretion in the metabolic syndrome?
What do high levels of circulating glucose and free fatty acids (FFAs) do to pancreatic insulin secretion in the metabolic syndrome?
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What is the relationship between leptin and insulin sensitivity in the context of leptin deficiency?
What is the relationship between leptin and insulin sensitivity in the context of leptin deficiency?
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How does hyperleptinemia impact individuals with leptin resistance?
How does hyperleptinemia impact individuals with leptin resistance?
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What is the effect of leptin resistance in the brain and other tissues?
What is the effect of leptin resistance in the brain and other tissues?
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How does the gut microbiome contribute to obesity and metabolic disorders?
How does the gut microbiome contribute to obesity and metabolic disorders?
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What is the effect of higher levels of circulating cytokines on hepatic production of C-reactive protein (CRP)?
What is the effect of higher levels of circulating cytokines on hepatic production of C-reactive protein (CRP)?
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In the context of insulin resistance, what mechanism contributes to increased triglyceride accumulation in the liver?
In the context of insulin resistance, what mechanism contributes to increased triglyceride accumulation in the liver?
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