Clinical BioChemistry 2: Enzymes Overview
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Questions and Answers

What suffix is attached to a description of the chemical reaction catalyzed by an enzyme?

  • -ase (correct)
  • -zyme
  • -reactase
  • -catalyse

What is the role of the active site in an enzyme molecule?

  • To convert the substrate to product
  • To increase the velocity of the reaction
  • To participate in substrate binding and catalysis (correct)
  • To bind the product

What is the result of the binding of the substrate to the enzyme?

  • A conformational change in the enzyme (correct)
  • The formation of a new product
  • The inhibition of the reaction
  • A conformational change in the substrate

What is the term for the number of molecules of substrate converted to product per enzyme molecule per second?

<p>Turnover number (B)</p> Signup and view all the answers

What is a characteristic of enzyme-catalyzed reactions?

<p>They are highly specific (B)</p> Signup and view all the answers

What is the term for RNAs with catalytic activity?

<p>Ribozymes (C)</p> Signup and view all the answers

What is the term for an active enzyme with its nonprotein component?

<p>Holoenzyme (D)</p> Signup and view all the answers

Which type of molecule is a cofactor?

<p>Metal ion (D)</p> Signup and view all the answers

What is the purpose of compartmentalization of enzymes in specific organelles within the cell?

<p>To isolate the reaction substrate or product from other competing reactions (C)</p> Signup and view all the answers

What is the term for the energy required to convert a substance from ground state to transition state?

<p>Activation energy (B)</p> Signup and view all the answers

What is the role of a catalyst in a chemical reaction?

<p>It accelerates the reaction (B)</p> Signup and view all the answers

How does the rate of an enzyme-catalyzed reaction change with an increase in substrate concentration?

<p>It increases gradually within a limited range (A)</p> Signup and view all the answers

What is the term for a small organic molecule that is required for enzymatic activity and transiently associates with the enzyme?

<p>Cosubstrate (C)</p> Signup and view all the answers

What is the term for the increase in enzyme velocity when the temperature is increased by 10°C?

<p>Q10 (D)</p> Signup and view all the answers

What is the theory that explains the action of catalysts?

<p>Transition state theory (C)</p> Signup and view all the answers

What is the typical temperature range for optimal enzyme activity?

<p>35°C-40°C (B)</p> Signup and view all the answers

Why do some enzymes, like Taq DNA polymerase, remain active at high temperatures?

<p>Due to their very stable structure and conformation (A)</p> Signup and view all the answers

How does the velocity of an enzyme reaction change with an increase in temperature?

<p>It increases gradually and then declines (D)</p> Signup and view all the answers

At what pH does the enzyme pepsin in the stomach work best?

<p>pH 2 (B)</p> Signup and view all the answers

What happens to enzyme activity when the product concentration increases?

<p>It decreases (D)</p> Signup and view all the answers

What is the effect of ultraviolet radiation on certain enzymes?

<p>It inhibits them (B)</p> Signup and view all the answers

What is the Michaelis constant (Km) representative of?

<p>The enzyme's affinity for its substrate (B)</p> Signup and view all the answers

What is the typical pH range at which most enzymes function?

<p>pH 6 to 8 (D)</p> Signup and view all the answers

What does a low value of Km indicate?

<p>Strong substrate-enzyme affinity (D)</p> Signup and view all the answers

What is the primary function of enzymes in the body?

<p>To channel reactants into useful pathways (D)</p> Signup and view all the answers

What suffix is commonly attached to the substrate of the reaction in enzyme names?

<p>-ase (A)</p> Signup and view all the answers

How many major classes of enzymes are there in the systematic naming system?

<p>6 (C)</p> Signup and view all the answers

What is the purpose of assigning two names to each enzyme?

<p>To identify enzymes without ambiguity (C)</p> Signup and view all the answers

What is the role of enzymes in biological reactions?

<p>To increase the rate of reactions (D)</p> Signup and view all the answers

What is the term for enzymes that retain their original trivial names?

<p>Trivial names (B)</p> Signup and view all the answers

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