Classification of Hormones Based on Chemical Nature

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Questions and Answers

Which of the following is NOT a characteristic of peptide or protein hormones?

  • Oxytocin is an example of a peptide hormone
  • Glucagon is an example of a peptide hormone
  • They are hydrophobic in nature (correct)
  • Insulin is an example of a peptide hormone

Which of the following is an example of a steroid hormone?

  • Oxytocin
  • Insulin
  • Estrogen (correct)
  • Glucagon

Which of the following hormones uses cyclic guanosine monophosphate (cGMP) as a second messenger?

  • Adrenocorticotropic hormone (ACTH)
  • Atrial natriuretic peptide (ANP) (correct)
  • Gastrin
  • Follicle-stimulating hormone (FSH)

Which of the following statements about Group I hormones is NOT true?

<p>They are hydrophilic in nature (B)</p> Signup and view all the answers

Which of the following categories of Group II hormones uses phosphatidylinositol/calcium as a second messenger?

<p>Hormones using phosphatidylinositol/calcium as second messenger (C)</p> Signup and view all the answers

Which of the following statements about amino acid derivatives is true?

<p>Epinephrine is an example of an amino acid derivative hormone (A)</p> Signup and view all the answers

Which of the following statements about hormone receptors is true?

<p>Some hormone receptors are located on the cell surface, while others are located within the cell (B)</p> Signup and view all the answers

Which of the following hormones uses cyclic adenosine monophosphate (cAMP) as a second messenger?

<p>Adrenaline (D)</p> Signup and view all the answers

Which of the following statements about the classification of hormones based on their mechanism of action is true?

<p>Group II hormones are divided into three categories based on their second messengers (C)</p> Signup and view all the answers

Which of the following hormones is NOT an example of a hormone that uses phosphatidylinositol/calcium as a second messenger?

<p>Parathormone (PTH) (B)</p> Signup and view all the answers

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Study Notes

Hormones Definition

  • Hormones are chemical messengers released from ductless glands into the bloodstream to regulate the activity of other tissues.

Classification of Hormones

  • Based on chemical nature:
    • Peptide or protein hormones: examples include insulin, glucagon, antidiuretic hormone, and oxytocin.
    • Steroid hormones: examples include glucocorticoids, mineralocorticoids, and sex hormones.
    • Amino acid derivatives: examples include epinephrine, norepinephrine, thyroxine (T4), and triiodothyronine (T3).

Classification Based on Mechanism of Action

Group I Hormones

  • Action is mediated via intracellular receptors.
  • Examples include glucocorticoids, estrogens, progesterone, mineralocorticoids, calcitriol, and thyroxine.

Group II Hormones

  • Action is mediated via cell surface receptors and second messengers.
  • Hydrophilic in nature.
  • Divided into three categories based on second messengers:
    • Hormones using cyclic adenosine monophosphate (cAMP) as second messenger:
      • Examples include adrenocorticotropic hormone (ACTH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), parathormone (PTH), and adrenaline.
    • Hormones using phosphatidylinositol/calcium as second messenger:
      • Examples include thyrotropin-releasing hormone (TRH), gonadotropin-releasing hormone (GnRH), gastrin, and chole cystokinin (CCK).
    • Hormones using cyclic guanosine monophosphate (cGMP) as second messenger:
      • Example is atrial natriuretic peptide (ANP).

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