Questions and Answers
What is the therapeutic classification of Citalopram?
What is the primary action of Citalopram?
Selectively inhibits the reuptake of serotonin in the CNS.
The initial dosage of Citalopram for adults is ___ mg once daily.
20
What are some indications for using Citalopram?
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Which of the following are potential side effects of Citalopram? (Select all that apply)
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What should be monitored as a nursing implication during therapy with Citalopram?
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Study Notes
Citalopram (Celexa) Overview
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Classification:
- Therapeutic: Antidepressants
- Pharmacologic: Selective serotonin reuptake inhibitors (SSRIs)
Mechanism of Action
- Selectively inhibits serotonin reuptake in the central nervous system (CNS)
- Provides antidepressant effects
Route and Dosage
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Adults:
- Initial: 20 mg once daily
- May increase to 40 mg/day after one week (maximum dose)
- For poor metabolizers of CYP2C19 or if on a CYP2C19 inhibitor: Do not exceed 20 mg/day
-
Geriatric Patients:
- Initial: 20 mg once daily (maximum 20 mg/day for patients 60 years and older)
-
Hepatic Impairment:
- Initial: 20 mg once daily (do not exceed 20 mg/day)
Indications
- Approved for treating depression
- Unlabeled uses include:
- Premenstrual dysphoric disorder (PMDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder
- Generalized anxiety disorder (GAD)
- Posttraumatic stress disorder (PTSD)
- Social anxiety disorder (social phobia)
Side Effects
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CNS:
- Neuroleptic malignant syndrome, suicidal thoughts, drowsiness, insomnia, confusion, agitation, anxiety, impaired concentration
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EENT:
- Abnormal accommodation
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Respiratory:
- Cough
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Cardiovascular:
- Torsade de Pointes, postural hypotension, QT interval prolongation
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Gastrointestinal:
- Abdominal pain, anorexia, diarrhea, dry mouth, nausea, vomiting, appetite changes
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Genitourinary:
- Amenorrhea, erectile dysfunction, polyuria
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Dermatological:
- Sweating, rash, photosensitivity
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Metabolic:
- Weight loss, weight gain
-
Miscellaneous:
- Hyponatremia, serotonin syndrome, fever, yawning
Toxic Symptoms
- Further details on specific toxic symptoms were not provided.
Nursing Implications
-
Assessment:
- Regularly monitor mood changes and suicidal tendencies, particularly during early therapy and dosage changes
- Restrict the amount of medication available to patients
- Awareness of increased risk factors in children, adolescents, and adults during treatment
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Enhance your understanding of Citalopram (Celexa) with these flashcards. Explore key terminology such as classification, action, and dosing instructions for effective antidepressant therapy. Perfect for students or professionals in the medical field.
