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Questions and Answers
What percentage of blood is found in the systemic arterial system?
What percentage of blood is found in the systemic arterial system?
- 15%
- 5%
- 13% (correct)
- 9%
Which of the following correctly identifies where blood is found in the pulmonary vessels?
Which of the following correctly identifies where blood is found in the pulmonary vessels?
- 9% (correct)
- 5%
- 12%
- 7%
In which component is a higher percentage of blood found: systemic capillaries or the heart?
In which component is a higher percentage of blood found: systemic capillaries or the heart?
- Neither has significant blood volume
- Heart
- Both are equal
- Systemic capillaries (correct)
Which of the following percentages represents blood in the heart?
Which of the following percentages represents blood in the heart?
Identify the component with the lowest blood percentage based on the given information.
Identify the component with the lowest blood percentage based on the given information.
What is the term used to describe the intermittent contraction and relaxation of smooth muscle in pre-capillaries and met arterioles?
What is the term used to describe the intermittent contraction and relaxation of smooth muscle in pre-capillaries and met arterioles?
How many times per minute does vasomotion typically occur?
How many times per minute does vasomotion typically occur?
Which of the following factors is NOT involved in the regulation of vasomotion?
Which of the following factors is NOT involved in the regulation of vasomotion?
What role do chemical signals play in vasomotion?
What role do chemical signals play in vasomotion?
Which statement accurately describes the flow pattern associated with vasomotion?
Which statement accurately describes the flow pattern associated with vasomotion?
What does cardiac output measure?
What does cardiac output measure?
Which term refers to the speed at which blood moves along a specific segment of circulation?
Which term refers to the speed at which blood moves along a specific segment of circulation?
How is blood flow velocity expressed?
How is blood flow velocity expressed?
What is a distinguishing feature of sinusoidal capillaries?
What is a distinguishing feature of sinusoidal capillaries?
Which of the following is NOT a factor that influences cardiac output?
Which of the following is NOT a factor that influences cardiac output?
If a person has a low cardiac output, what might this indicate?
If a person has a low cardiac output, what might this indicate?
What type of basement membrane do sinusoidal capillaries possess?
What type of basement membrane do sinusoidal capillaries possess?
Which of the following statements is true regarding the endothelium of sinusoidal capillaries?
Which of the following statements is true regarding the endothelium of sinusoidal capillaries?
What is the prevalence of sinusoidal capillaries compared to other types?
What is the prevalence of sinusoidal capillaries compared to other types?
Which structure of sinusoidal capillaries allows for greater exchange of substances?
Which structure of sinusoidal capillaries allows for greater exchange of substances?
What is a distinctive characteristic of laminar flow in blood vessels?
What is a distinctive characteristic of laminar flow in blood vessels?
Why is laminar flow considered the most efficient pattern of flow?
Why is laminar flow considered the most efficient pattern of flow?
Which of the following statements is NOT true regarding laminar flow?
Which of the following statements is NOT true regarding laminar flow?
In what manner does fluid behave during laminar flow?
In what manner does fluid behave during laminar flow?
Which scenario is most likely to disrupt laminar flow in blood vessels?
Which scenario is most likely to disrupt laminar flow in blood vessels?
What does viscosity refer to in the context of fluid dynamics?
What does viscosity refer to in the context of fluid dynamics?
What phenomenon is described as occurring due to high blood flow velocity?
What phenomenon is described as occurring due to high blood flow velocity?
In the context of arterial walls, what condition might be indicated by a rough surface?
In the context of arterial walls, what condition might be indicated by a rough surface?
Which of the following best describes arteriovenous shunts?
Which of the following best describes arteriovenous shunts?
Which of the following definitions did Isaac Newton provide for viscosity?
Which of the following definitions did Isaac Newton provide for viscosity?
Flashcards
Where is the majority of blood found?
Where is the majority of blood found?
The systemic arterial system is responsible for carrying oxygenated blood from the heart to the rest of the body. It holds a significant portion of the body's blood volume.
What system holds the least amount of blood?
What system holds the least amount of blood?
The systemic capillary system is responsible for exchanging oxygen and nutrients with cells throughout the body. It plays a critical role in tissue perfusion.
Describe capillaries.
Describe capillaries.
Capillaries are a vital component of the circulatory system responsible for exchanging materials between blood and tissues. They are highly branched and thin-walled to facilitate efficient diffusion of oxygen, nutrients, and waste products.
What system transports blood to and from the lungs for gas exchange?
What system transports blood to and from the lungs for gas exchange?
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What determines a high-pressure system?
What determines a high-pressure system?
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Laminar Flow
Laminar Flow
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Most Efficient Blood Flow
Most Efficient Blood Flow
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Cardiac Output
Cardiac Output
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Blood Flow Velocity
Blood Flow Velocity
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Blood Flow Velocity Unit
Blood Flow Velocity Unit
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Aorta
Aorta
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Left Ventricle
Left Ventricle
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What is vasomotion?
What is vasomotion?
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How is vasomotion regulated locally?
How is vasomotion regulated locally?
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How is vasomotion regulated by the sympathetic nervous system?
How is vasomotion regulated by the sympathetic nervous system?
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Sinusoidal Capillary
Sinusoidal Capillary
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What are pre-capillary sphincters?
What are pre-capillary sphincters?
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Endothelium in Sinusoids
Endothelium in Sinusoids
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What are met-arterioles?
What are met-arterioles?
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Basement Membrane in Sinusoids
Basement Membrane in Sinusoids
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Intercellular Gaps in Sinusoids
Intercellular Gaps in Sinusoids
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Discontinuous Structure of Sinusoids
Discontinuous Structure of Sinusoids
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Viscosity
Viscosity
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Bruit
Bruit
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Arterio-venous shunts
Arterio-venous shunts
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Rough surface of arterial wall
Rough surface of arterial wall
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Viscosity (Newton's Definition)
Viscosity (Newton's Definition)
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Study Notes
Vascular Physiology
- Circulation is divided into pulmonary and systemic circulation
- 84% of the blood is found in systemic circulation, including 64% in veins, 13% in systemic arteries, and 7% in systemic capillaries
- 7% of blood is in the heart
- 9% of the blood is in pulmonary vessels
- Systemic circulation is a high-pressure system, including the arterial system and left ventricles
- Systemic veins, pulmonary circulation, and heart chambers other than the left ventricle are part of the low-pressure system
Functional Morphology of Arteries
- Arteries are categorized into large elastic arteries (windkessel vessels), medium muscular arteries (distribution vessels), and arterioles (resistance vessels)
- Arterioles are the smallest branches of arteries and are under high pressure
- Artery walls have layers to maintain structure and function
Arterioles
- Arterioles are the primary regulators of blood flow into capillaries
- Arterioles have a high smooth muscle content in walls
- Arterioles are extensively innervated by autonomic nerve fibers
- Alpha 1 adrenergic receptors are found on arterioles of skin, splanchnic organs, spleen, and kidney
- Beta 2 adrenergic receptors are found on arterioles of skeletal muscle
Capillaries
- Capillaries are exchange vessels with the largest total cross-sectional and surface area
- Capillary walls are only one cell thick (simple squamous epithelium) with a basal lamina
- Capillaries are thin-walled and have no muscle or elastic valve
- Capillaries exchange nutrients, water, and gases
- Capillaries have a small diameter (4-9 micrometers), allowing small molecules and cells to pass
- Capillaries have a short transit time for blood flow, allowing for efficient exchange of materials within the tissues
Functional Morphology of Capillaries
- Arterioles divide into smaller muscle or walled vessels called meta-arterioles, feeding into capillaries
- A meta-arteriole is slightly larger than a capillary and has both arteriole and capillary characteristics
- Has smooth muscle that is not continuous
- Has individual smooth muscle cells placed short distances apart
- Constricting narrows or shuts off blood flow through capillary beds
Capillaries (Exchange Vessels)
- Capillaries have the largest total cross-sectional area and surface area compared to other vessels
- Capillary wall is composed of a single layer of endothelial cells and a thin basal lamina
- The main function of capillaries is the exchange of nutrients, waste products, and gases
- Capillaries are the location of gas and nutrient exchange between blood and tissues
- Due to their structure, there is a low pressure in capillaries compared to the arterial side
Types of Capillaries
- Continuous capillaries have tight junctions between endothelial cells, allowing passage for small molecules and water but not large proteins
- Fenestrated capillaries have pores (fenestrations) in their endothelial cells, allowing for faster exchange of fluids and molecules
- Sinusoidal capillaries (discontinuous capillaries) have large intercellular gaps and incomplete basement membranes, resulting in the largest exchange ability, accommodating larger molecules
Venules
- Venules are extremely small veins (8-100 micrometers) that collect blood from capillaries and progressively merge to form larger veins. The largest vein, the vena cava, returns blood to the heart
- Venules are characterized by their thin walls, which are easily distended, and contain little elastic tissue or smooth muscles
- Venules are under low pressure
- Venules have á, -adrenergic receptors
- Venules have valves
Blood Velocity and Viscosity
- Blood flow is the amount of blood that passes a given point in the circulation in a set period
- Blood velocity is the speed at which blood flows through a particular segment
- Viscosity is the resistance to fluid flow due to internal friction between layers
- Blood viscosity depends on plasma protein concentration, and hematocrit (packed red cell volume)
Turbulent Flow
- Turbulent flow is characterized by crosscurrents (eddies) and the fastest velocities aren't necessarily in the center
- High velocity and sudden changes in the diameter of the vessel contribute to turbulent flow
- Large vessel diameter, sharp turns, and rough surfaces contribute to turbulent flow
- Low viscosity and high-density fluids tend to resist turbulent flow
Murmurs and Bruits
- Murmurs are abnormal heart sounds due to turbulent flow of blood in the heart, arising from valve problems or other heart defects
- Bruits are abnormal sounds caused by turbulent blood flow in arteries, often associated with narrowing or blockage of arteries
Viscosity
- Viscosity is a measure of the resistance of a fluid to flow
- Viscosity is related to the thickness of the fluid
- Some factors that affect viscosity include temperature and erythrocyte (red blood cell) count
- Blood viscosity is higher than water's viscosity
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