Chronic Toxicity and Carcinogenicity Quiz
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Questions and Answers

What are the two stages of carcinogenicity in the multistage process that can lead to cancer?

  • Initiation and promotion (correct)
  • Transformation and metastasis
  • Mutation and progression
  • Benign and malignant

Which chronic toxic effect is commonly observed in coal miners?

  • Cirrhosis
  • Chronic kidney disease
  • Pulmonary fibrosis (correct)
  • Chronic bronchitis

What distinguishes benign tumors from malignant tumors?

  • Malignant tumors are treatable.
  • Benign tumors invade adjacent tissues.
  • Benign tumors are uncontrolled growths of cells.
  • Malignant tumors metastasize to distant sites. (correct)

Which term is used to describe cumulative damage to specific organ systems over many months or years?

<p>Chronic toxicity (D)</p> Signup and view all the answers

What process involves a normal cell undergoing irreversible changes due to mutation of cellular genes?

<p>Initiation (B)</p> Signup and view all the answers

Which disease is commonly observed in long-term cigarette smokers as a chronic toxic effect?

<p>Chronic bronchitis (A)</p> Signup and view all the answers

Which type of toxicity results from repeated exposure for several weeks or months?

<p>Chronic Toxicity (C)</p> Signup and view all the answers

What is the term used to describe toxic effects occurring at multiple sites?

<p>Systemic Toxicity (C)</p> Signup and view all the answers

Which type of toxicity occurs almost immediately after exposure?

<p>Acute Toxicity (B)</p> Signup and view all the answers

What is the term for the toxic effect that occurs at only one specific site?

<p>Specific Target Organ Toxicity (C)</p> Signup and view all the answers

In the context of toxic effects, which type is characterized by repeated exposure over several weeks or months?

<p>Subchronic Toxicity (A)</p> Signup and view all the answers

Which type of toxicity can lead to internal bleeding when ingesting certain medications over several weeks?

<p>Chronic Toxicity (B)</p> Signup and view all the answers

What term is used to describe the toxic effect that occurs at only one or two organs?

<p>Localized toxicity (D)</p> Signup and view all the answers

In pharmacologic and toxicologic interactions, what type of effect occurs when the combined effect of two chemicals is equal to the sum of the effects of each agent given alone?

<p>Additive effect (C)</p> Signup and view all the answers

Which term is used to describe cumulative damage to specific organ systems over many months or years?

<p>Chronic toxicity (D)</p> Signup and view all the answers

What distinguishes benign tumors from malignant tumors in terms of carcinogenicity?

<p>Metastasis potential (D)</p> Signup and view all the answers

Which clinical disease is commonly observed as a chronic toxic effect in coal miners?

<p>Black lung disease (C)</p> Signup and view all the answers

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