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Questions and Answers
What is the purpose of an LD50 test?
What is the purpose of an LD50 test?
- To determine the acute toxicity of a substance
- To determine the reproductive toxicity of a substance
- To determine the lethal dose of a substance in 50% of test subjects (correct)
- To determine the chronic toxicity of a substance
Which of the following is NOT a method used for determining toxicity?
Which of the following is NOT a method used for determining toxicity?
- Acute toxicity test
- Sediment toxicity test (correct)
- Chronic toxicity test
- LD50 test
What is the difference between acute and chronic toxicity tests?
What is the difference between acute and chronic toxicity tests?
- Acute tests measure the immediate effects of a substance, while chronic tests measure the long-term effects (correct)
- Acute tests are conducted on humans, while chronic tests are conducted on animals
- Chronic tests measure the immediate effects of a substance, while acute tests measure the long-term effects
- Chronic tests are conducted on humans, while acute tests are conducted on animals
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Study Notes
Toxicity Tests
- LD50 test determines the dose of a substance that can kill 50% of test subjects, used to measure acute toxicity
- LD50 test is NOT used to determine chronic toxicity or long-term effects of a substance
Determining Toxicity Methods
- Methods used to determine toxicity include in vitro tests, in vivo tests, and epidemiological studies
- NOT a method used for determining toxicity: personal opinions or anecdotal evidence
Acute vs Chronic Toxicity
- Acute toxicity tests measure the adverse effects of a substance after a single dose or short-term exposure
- Chronic toxicity tests measure the adverse effects of a substance after long-term or repeated exposure
- Key difference: duration of exposure and potential for cumulative effects
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