12 Questions
Which type of mutation involves the addition or removal of nucleotide pairs?
Insertions and Deletions
What type of mutation results in changes in the reading frame of the gene?
Insertions and Deletions
Which type of chromosome mutation involves the alteration of the structure of chromosomes?
Chromosome rearrangements
What type of genetic mutation occurs when the number of nucleotides inserted or deleted is not a multiple of three?
Frameshift mutations
What is the role of IF-3 in prokaryotic initiation?
Preventing the large ribosomal subunit from binding during initiation
What function does the Shine–Dalgarno sequence serve in prokaryotic translation?
Allows the ribosome to attach to the mRNA and position it over the initiation codon
What is the role of the cap at the 5′ end of eukaryotic mRNA in translation initiation?
Playing a critical role in the initiation of translation
What is the function of the initiator tRNA in eukaryotic initiation complex?
Forming an initiation complex with the small subunit of eukaryotic ribosome
What is the result of frameshift mutations on the encoded amino acids?
They alter all amino acids following the mutation
What are in-frame insertions and deletions?
Mutations that do not affect the reading frame
What is the characteristic of repetitive sequences involved in trinucleotide repeat expansions?
They consist of three nucleotides repeated in tandem
How does the number of nucleotide repeats in expanding nucleotide repeats relate to disease severity?
It often correlates with disease severity
Explore the types of chromosome mutations and the distinction between transitions and transversions. Learn about chromosome classification and the impact of chromosome rearrangements on genetic structure.
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