Chromosomal Anomalies and Genetic Information Organization
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Questions and Answers

What is the primary function of chromosomes?

  • To carry the genomic information from cell to cell (correct)
  • To regulate cell division
  • To produce proteins in the cell
  • To store energy for the cell

    • What is the first step in the compaction of DNA?

  • Winding of DNA onto histones (correct)
  • Formation of double helix structure
  • Unwinding of DNA from histones
  • Formation of nucleosomes

    • Which protein is most abundant in the cell and is involved in the compaction of DNA?

  • H3O
  • H1
  • Histone (correct)
  • H2O

    • What is the function of fluorescent in situ hybridisation (FISH)?

    <p>Detection of chromosomal abnormalities</p> Signup and view all the answers

    How are the two strands of the DNA double helix held together?

    <p>By hydrogen bonding in an anti-parallel orientation</p> Signup and view all the answers

    What is the role of linker DNA in nucleosomes?

    <p>It forms the 'bead-on-a-string' structure with nucleosomes</p> Signup and view all the answers

    In a healthy individual, what is the chromosomal composition of a female?

    <p>XX</p> Signup and view all the answers

    What technique can be used for staining in karyotyping?

    <p>Fluorescent in situ hybridisation (FISH)</p> Signup and view all the answers

    Why does G-Banding give chromosomes a striped appearance?

    <p>It stains the regions of DNA rich in adenine (A) and thymine (T) base pairs</p> Signup and view all the answers

    What is the purpose of spectral karyotyping (SKY) in karyotyping?

    <p>Molecular cytogenetic analysis using spectral microscopy</p> Signup and view all the answers

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