10 Questions
What is the primary function of chromosomes?
To carry the genomic information from cell to cell
What is the first step in the compaction of DNA?
Winding of DNA onto histones
Which protein is most abundant in the cell and is involved in the compaction of DNA?
Histone
What is the function of fluorescent in situ hybridisation (FISH)?
Detection of chromosomal abnormalities
How are the two strands of the DNA double helix held together?
By hydrogen bonding in an anti-parallel orientation
What is the role of linker DNA in nucleosomes?
It forms the 'bead-on-a-string' structure with nucleosomes
In a healthy individual, what is the chromosomal composition of a female?
XX
What technique can be used for staining in karyotyping?
Fluorescent in situ hybridisation (FISH)
Why does G-Banding give chromosomes a striped appearance?
It stains the regions of DNA rich in adenine (A) and thymine (T) base pairs
What is the purpose of spectral karyotyping (SKY) in karyotyping?
Molecular cytogenetic analysis using spectral microscopy
Test your knowledge on chromosomal anomalies, sex determination, chromosome abnormalities, and karyotyping. This quiz covers how genetic information is organized as chromosomes and the significance of numerical and structural chromosome abnormalities.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
