Chromodomain and Bromodomain Proteins in Chromatin Formation
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Questions and Answers

What effect does methylation have on chromatin structure?

  • Recruits bromodomain proteins to maintain euchromatin conformation
  • Neutralizes the positive charge of lysine
  • Contributes to heterochromatin conformation (correct)
  • Reduces histone-DNA interactions

    • How does acetylation influence gene expression?

  • Neutralizes the positive charge of lysine
  • Reduces histone-DNA interactions
  • Recruits chromodomain proteins that condense chromatin
  • Facilitates transcription (correct)

    • What is the role of histone acetyl transferases (HATs) in histone modification?

  • Maintain heterochromatin conformation
  • Add acetyl groups to lysine residues (correct)
  • Recruit chromodomain proteins
  • Remove acetyl groups from lysine residues

    • Which modification allows promoter regions to be accessible for RNA polymerase?

    <p>Acetylation</p> Signup and view all the answers

    How do histone deacetyl transferases (HDACs) contribute to gene regulation?

    <p>Remove acetyl groups from lysine residues</p> Signup and view all the answers

    Which protein is recruited by methylation to further condense the chromatin?

    <p>Chromodomain proteins</p> Signup and view all the answers

    In what way does acetylation influence histone-DNA interactions?

    <p>Reduces interactions</p> Signup and view all the answers

    Which process is associated with euchromatin conformation?

    <p>Active transcription</p> Signup and view all the answers

    How does phosphorylation contribute to chromatin structure?

    <p>Maintains open state of chromatin</p> Signup and view all the answers

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