Podcast
Questions and Answers
What effect does methylation have on chromatin structure?
What effect does methylation have on chromatin structure?
- Recruits bromodomain proteins to maintain euchromatin conformation
- Neutralizes the positive charge of lysine
- Contributes to heterochromatin conformation (correct)
- Reduces histone-DNA interactions
How does acetylation influence gene expression?
How does acetylation influence gene expression?
- Neutralizes the positive charge of lysine
- Reduces histone-DNA interactions
- Recruits chromodomain proteins that condense chromatin
- Facilitates transcription (correct)
What is the role of histone acetyl transferases (HATs) in histone modification?
What is the role of histone acetyl transferases (HATs) in histone modification?
- Maintain heterochromatin conformation
- Add acetyl groups to lysine residues (correct)
- Recruit chromodomain proteins
- Remove acetyl groups from lysine residues
Which modification allows promoter regions to be accessible for RNA polymerase?
Which modification allows promoter regions to be accessible for RNA polymerase?
How do histone deacetyl transferases (HDACs) contribute to gene regulation?
How do histone deacetyl transferases (HDACs) contribute to gene regulation?
Which protein is recruited by methylation to further condense the chromatin?
Which protein is recruited by methylation to further condense the chromatin?
In what way does acetylation influence histone-DNA interactions?
In what way does acetylation influence histone-DNA interactions?
Which process is associated with euchromatin conformation?
Which process is associated with euchromatin conformation?
How does phosphorylation contribute to chromatin structure?
How does phosphorylation contribute to chromatin structure?