lecture 4
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Questions and Answers

What is the role of the brain-specific enhancer in the expression of gene A?

  • Binding to the Mediator and stabilizing RNA polymerase II at the promoter
  • Activating Pax6 in the pancreas
  • Causing gene A to be transcribed in brain cells only (correct)
  • Directing Pax6 gene expression in the neural tube

    • Which transcription factors are required to activate Pax6 in the pancreas?

  • Meis transcription factors
  • Pbx1 and Meis transcription factors (correct)
  • Transcription factors binding to the limb enhancer
  • Brain-specific transcription factors

    • What happens if the limb enhancer cannot bind to the transcription factors of a cell type?

  • The gene is not transcribed in any cell type (correct)
  • The gene is transcribed in brain cells
  • The limb enhancer binds to the Mediator and stabilizes RNA polymerase II at the promoter
  • The gene is transcribed in limb cells only

    • What is the role of the Pax6 protein in tissue development?

    <p>Being critical in the development of various tissues (D)</p> Signup and view all the answers

    In which tissues does the pancreas-specific enhancer direct Pax6 gene expression?

    <p>Pancreas, lens, cornea, retina, and neural tube (B)</p> Signup and view all the answers

    What is the outcome of brain specific transcription factors binding to the brain enhancer?

    <p>Stabilizing RNA polymerase II at the promoter (C)</p> Signup and view all the answers

    Which cells show expression of gene A based on in situ hybridization?

    <p>Limb and brain cells (D)</p> Signup and view all the answers

    What must be present to activate Pax6 in the pancreas based on DNA sequence of the pancreas-specific enhancer element?

    <p>(Pbx1 and Meis) transcription factors (D)</p> Signup and view all the answers

    "Enhancers" are involved in directing gene expression through interaction with:

    <p>Transcription factors (B)</p> Signup and view all the answers

    What cellular process is specifically happening in the described scenario?

    <p>Nuclear division (B)</p> Signup and view all the answers

    What cytoskeletal elements are mentioned as creating nuclei as islands?

    <p>Intermediate filaments (C)</p> Signup and view all the answers

    What is NOT happening in the described scenario?

    <p>Cytokinesis (A)</p> Signup and view all the answers

    What is the main function of the highlighted cytoskeletal elements in the scenario?

    <p>Creating nuclear islands (B)</p> Signup and view all the answers

    Which phase of the cell cycle is specifically referred to in the scenario?

    <p>S phase (A)</p> Signup and view all the answers

    What is the primary focus of the described scenario?

    <p>Nuclear dynamics (A)</p> Signup and view all the answers

    What is the key event that occurs during nuclear division according to the scenario?

    <p>DNA recombination (A)</p> Signup and view all the answers

    Which specific cellular component is NOT mentioned in the scenario?

    <p>$\delta$-myosin (B)</p> Signup and view all the answers

    What is NOT a focus of the video mentioned in the scenario?

    <p>Stellular movement (D)</p> Signup and view all the answers

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