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Questions and Answers
What is the role of histone acetylation by histone acetyltransferases (HATs) in chromatin structure?
What is the role of histone acetylation by histone acetyltransferases (HATs) in chromatin structure?
- Substitutes specialized histone variants into chromatin
- Causes decondensing of chromatin (correct)
- Shifts nucleosomes along the DNA
- Causes chromatin condensation
Which mechanism causes chromatin to become tightly closed?
Which mechanism causes chromatin to become tightly closed?
- ATP-dependent changes in nucleosome positioning
- Substitution of specialized histone variants
- Histone acetylation by HATs
- Methylation of histone proteins (correct)
What effect does methylation have on chromatin structure?
What effect does methylation have on chromatin structure?
- Causes decondensing of chromatin
- Substitutes specialized histone variants into chromatin
- Leads to tightly closed chromatin (correct)
- Shifts nucleosomes along the DNA
Which process results in shifts of nucleosomes along the DNA?
Which process results in shifts of nucleosomes along the DNA?
What is the role of specialized histone variants in chromatin structure?
What is the role of specialized histone variants in chromatin structure?
What is the main effect of acetylation by histone acetyltransferases (HATs) on chromatin structure?
What is the main effect of acetylation by histone acetyltransferases (HATs) on chromatin structure?
Which process is responsible for homologous proteins with extensions having different functions being substituted into chromatin?
Which process is responsible for homologous proteins with extensions having different functions being substituted into chromatin?
What effect does methylation have on chromatin structure?
What effect does methylation have on chromatin structure?
Which mechanism involves ATP-dependent changes that result in shifting nucleosomes along the DNA?
Which mechanism involves ATP-dependent changes that result in shifting nucleosomes along the DNA?
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Study Notes
Regulation of Chromatin Structure
- Chromatin structure is controlled and changed by at least three mechanisms:
ATP-dependent changes in nucleosome positioning
- Involve shifts of nucleosomes along the DNA
Posttranslational chemical modifications of histone proteins
- Acetylation by histone acetyltransferases (HATs) leads to decondensing of chromatin
- Methylation causes chromatin to become tightly closed
Substitution of specialized histone variants into chromatin
- Proteins are homologous to the common histones, but with extensions that have different functions
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